Stuart D. Shumway, Ph.D.
Affiliations: | 2001 | University of Wisconsin, Madison, Madison, WI |
Area:
Molecular Biology, Cell Biology, ImmunologyGoogle:
"Stuart Shumway"Parents
Sign in to add mentorShigeki Miyamoto | grad student | 2001 | UW Madison | |
(The constitutive proteolysis of IkappaBalpha in B-lymphocytes maintains NF-kappaB activity.) |
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Publications
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Celano SL, Yco LP, Kortus MG, et al. (2019) Identification of Kinases Responsible for p53-Dependent Autophagy. Iscience. 15: 109-118 |
Guertin AD, Li J, Liu Y, et al. (2013) Preclinical evaluation of the WEE1 inhibitor MK-1775 as single-agent anticancer therapy. Molecular Cancer Therapeutics. 12: 1442-52 |
Aarts M, Sharpe R, Garcia-Murillas I, et al. (2012) Forced mitotic entry of S-phase cells as a therapeutic strategy induced by inhibition of WEE1. Cancer Discovery. 2: 524-39 |
O'Connor S, Shumway S, Miyamoto S. (2005) Inhibition of IkappaBalpha nuclear export as an approach to abrogate nuclear factor-kappaB-dependent cancer cell survival. Molecular Cancer Research : McR. 3: 42-9 |
O'Connor S, Shumway SD, Amanna IJ, et al. (2004) Regulation of constitutive p50/c-Rel activity via proteasome inhibitor-resistant IkappaBalpha degradation in B cells. Molecular and Cellular Biology. 24: 4895-908 |
Shumway SD, Miyamoto S. (2004) A mechanistic insight into a proteasome-independent constitutive inhibitor kappaBalpha (IkappaBalpha) degradation and nuclear factor kappaB (NF-kappaB) activation pathway in WEHI-231 B-cells. The Biochemical Journal. 380: 173-80 |
Shumway SD, Berchtold CM, Gould MN, et al. (2002) Evidence for unique calmodulin-dependent nuclear factor-kappaB regulation in WEHI-231 B cells. Molecular Pharmacology. 61: 177-85 |
Huang TT, Wuerzberger-Davis SM, Seufzer BJ, et al. (2000) NF-kappaB activation by camptothecin. A linkage between nuclear DNA damage and cytoplasmic signaling events. The Journal of Biological Chemistry. 275: 9501-9 |
Shumway SD, Maki M, Miyamoto S. (1999) The PEST domain of IkappaBalpha is necessary and sufficient for in vitro degradation by mu-calpain. The Journal of Biological Chemistry. 274: 30874-81 |
Miyamoto S, Seufzer BJ, Shumway SD. (1998) Novel IkappaB alpha proteolytic pathway in WEHI231 immature B cells. Molecular and Cellular Biology. 18: 19-29 |