Hestia S. Mellert, Ph.D.
Affiliations: | 2011 | University of Pennsylvania, Philadelphia, PA, United States |
Area:
Molecular Biology, Cell BiologyGoogle:
"Hestia Mellert"Parents
Sign in to add mentorSteven B. McMahon | grad student | 2011 | Penn | |
(Regulating p53-mediated apoptosis by modulating DNA-binding domain acetylation.) |
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Publications
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Oran AR, Adams CM, Zhang XY, et al. (2016) Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer. Oncotarget |
Monteith JA, Mellert H, Sammons MA, et al. (2016) A rare DNA contact mutation in cancer confers p53 gain-of-function and tumor cell survival via TNFAIP8 induction. Molecular Oncology |
Thangavel C, Boopathi E, Ciment S, et al. (2014) The retinoblastoma tumor suppressor modulates DNA repair and radioresponsiveness. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 5468-82 |
Allen MA, Andrysik Z, Dengler VL, et al. (2014) Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms. Elife. 3: e02200 |
Mellert H, Espinosa JM. (2013) Tumor suppression by p53: is apoptosis important or not? Cell Reports. 3: 1335-6 |
Den RB, Ciment S, Sharma A, et al. (2012) Differential response of prostate cancer cells to ionizing radiation: The RB status. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 106 |
Yuan H, Rossetto D, Mellert H, et al. (2012) MYST protein acetyltransferase activity requires active site lysine autoacetylation. The Embo Journal. 31: 58-70 |
Den RB, Ciment S, Sharma A, et al. (2011) Relationship between the loss of the retinoblastoma tumor suppressor and radiosensitivity. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 34 |
Zhang XY, Pfeiffer HK, Mellert HS, et al. (2011) Inhibition of the single downstream target BAG1 activates the latent apoptotic potential of MYC. Molecular and Cellular Biology. 31: 5037-45 |
Charvet C, Wissler M, Brauns-Schubert P, et al. (2011) Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53. Molecular Cell. 42: 584-96 |