Keli N. Kolegraff, Ph.D.

Affiliations: 
2011 Biological and Biomedical Sciences Emory University, Atlanta, GA 
Area:
Cell Biology, Molecular Biology, Oncology
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"Keli Kolegraff"

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Asma Nusrat grad student 2011 Emory
 (Regulation of intestinal epithelial homeostasis by the desmosomal cadherins.)
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Publications

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Nava P, Kamekura R, Quirós M, et al. (2014) IFNγ-induced suppression of β-catenin signaling: evidence for roles of Akt and 14.3.3ζ. Molecular Biology of the Cell. 25: 2894-904
Kamekura R, Kolegraff KN, Nava P, et al. (2014) Loss of the desmosomal cadherin desmoglein-2 suppresses colon cancer cell proliferation through EGFR signaling. Oncogene. 33: 4531-6
Brazil JC, Liu R, Sumagin R, et al. (2013) α3/4 Fucosyltransferase 3-dependent synthesis of Sialyl Lewis A on CD44 variant containing exon 6 mediates polymorphonuclear leukocyte detachment from intestinal epithelium during transepithelial migration. Journal of Immunology (Baltimore, Md. : 1950). 191: 4804-17
Nava P, Kamekura R, Medina-Contreras O, et al. (2012) The Inflammatory Cytokine IFNg Regulates Intestinal Epithelial Homeostasis by Controlling the Spatiotemporal Localization of Akt, 14.3.3z and Beta-catenin Inflammatory Bowel Diseases. 18: S96
Gonzalez RS, Kolegraff K, Nusrat A, et al. (2012) Intercellular Junction Complex Protein Alterations in Ulcerative Colitis and Dysplasia American Journal of Clinical Pathology. 138: A225-A225
Kolegraff K, Nava P, Laur O, et al. (2011) Characterization of full-length and proteolytic cleavage fragments of desmoglein-2 in native human colon and colonic epithelial cell lines. Cell Adhesion & Migration. 5: 306-14
Nava P, Capaldo CT, Koch S, et al. (2011) JAM-A regulates epithelial proliferation through Akt/β-catenin signalling. Embo Reports. 12: 314-20
Kolegraff K, Nava P, Helms MN, et al. (2011) Loss of desmocollin-2 confers a tumorigenic phenotype to colonic epithelial cells through activation of Akt/β-catenin signaling. Molecular Biology of the Cell. 22: 1121-34
Nava-Dominguez P, Kolegraff K, Parkos C, et al. (2011) IFNγ influences epithelial proliferation by modulating Akt-β catenin signaling downstream of cadherins Inflammatory Bowel Diseases. 17: S71-S72
Brazil J, Sumagin R, Kolegraff K, et al. (2011) Glycosylation of CD44v6: Role of sialyl Lewis A in late events during neutrophil transepithelial migration Inflammatory Bowel Diseases. 17: S10
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