Erik K. Pacyniak, Ph.D.
Affiliations: | 2010 | Pharmacology, Toxicology & Therapeutics | University of Kansas, Lawrence, KS, United States |
Area:
ToxicologyGoogle:
"Erik Pacyniak"Parents
Sign in to add mentor| Grace L. Guo | grad student | 2010 | University of Kansas | |
| (Molecular mechanism of polybrominated diphenyl ether disposition in the liver.) | ||||
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Publications
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| Pacyniak E, Hagenbuch B, Klaassen CD, et al. (2011) Organic anion transporting polypeptides in the hepatic uptake of PBDE congeners in mice. Toxicology and Applied Pharmacology. 257: 23-31 |
| Pacyniak E, Roth M, Hagenbuch B, et al. (2010) Mechanism of polybrominated diphenyl ether uptake into the liver: PBDE congeners are substrates of human hepatic OATP transporters. Toxicological Sciences : An Official Journal of the Society of Toxicology. 115: 344-53 |
| Hill MS, Ruiz A, Pacyniak E, et al. (2008) Modulation of the severe CD4+ T-cell loss caused by a pathogenic simian-human immunodeficiency virus by replacement of the subtype B vpu with the vpu from a subtype C HIV-1 clinical isolate. Virology. 371: 86-97 |
| Pacyniak EK, Cheng X, Cunningham ML, et al. (2007) The flame retardants, polybrominated diphenyl ethers, are pregnane X receptor activators. Toxicological Sciences : An Official Journal of the Society of Toxicology. 97: 94-102 |
| Hout DR, Gomez LM, Pacyniak E, et al. (2006) A single amino acid substitution within the transmembrane domain of the human immunodeficiency virus type 1 Vpu protein renders simian-human immunodeficiency virus (SHIV(KU-1bMC33)) susceptible to rimantadine. Virology. 348: 449-61 |
| Hout DR, Gomez ML, Pacyniak E, et al. (2006) Substitution of the transmembrane domain of Vpu in simian-human immunodeficiency virus (SHIVKU1bMC33) with that of M2 of influenza A results in a virus that is sensitive to inhibitors of the M2 ion channel and is pathogenic for pig-tailed macaques. Virology. 344: 541-59 |
| Hout DR, Gomez ML, Pacyniak E, et al. (2005) Scrambling of the amino acids within the transmembrane domain of Vpu results in a simian-human immunodeficiency virus (SHIVTM) that is less pathogenic for pig-tailed macaques. Virology. 339: 56-69 |
| Pacyniak E, Gomez ML, Gomez LM, et al. (2005) Identification of a region within the cytoplasmic domain of the subtype B Vpu protein of human immunodeficiency virus type 1 (HIV-1) that is responsible for retention in the golgi complex and its absence in the Vpu protein from a subtype C HIV-1. Aids Research and Human Retroviruses. 21: 379-94 |
| Gomez LM, Pacyniak E, Flick M, et al. (2005) Vpu-mediated CD4 down-regulation and degradation is conserved among highly divergent SIV(cpz) strains. Virology. 335: 46-60 |
| Hout DR, Mulcahy ER, Pacyniak E, et al. (2004) Vpu: a multifunctional protein that enhances the pathogenesis of human immunodeficiency virus type 1. Current Hiv Research. 2: 255-70 |