Aruna M. Somasiri, Ph.D.

Affiliations: 
2004 University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Cell Biology, Oncology, Molecular Biology
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"Aruna Somasiri"

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C Roskelley grad student 2004 UBC
 (Molecular regulators of apical /basal polarity during mammary epithelial morphogenesis and invasive tumor progression.)
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Publications

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Tognon CE, Somasiri AM, Evdokimova VE, et al. (2011) ETV6-NTRK3-mediated breast epithelial cell transformation is blocked by targeting the IGF1R signaling pathway. Cancer Research. 71: 1060-70
Somasiri A, Nielsen JS, Makretsov N, et al. (2004) Overexpression of the anti-adhesin podocalyxin is an independent predictor of breast cancer progression. Cancer Research. 64: 5068-73
Tognon CE, Mackereth CD, Somasiri AM, et al. (2004) Mutations in the SAM domain of the ETV6-NTRK3 chimeric tyrosine kinase block polymerization and transformation activity. Molecular and Cellular Biology. 24: 4636-50
Ward KR, Zhang KX, Somasiri AM, et al. (2004) Expression of activated M-Ras in a murine mammary epithelial cell line induces epithelial-mesenchymal transition and tumorigenesis Oncogene. 23: 1187-1196
Somasiri A, Wu C, Ellchuk T, et al. (2001) Phosphatidylinositol 3-kinase is required for adherens junction-dependent mammary epithelial cell spheroid formation. Differentiation; Research in Biological Diversity. 66: 116-25
Roskelley CD, Wu C, Somasiri AM. (2000) Analysis of mammary gland morphogenesis. Methods in Molecular Biology (Clifton, N.J.). 136: 27-38
Somasiri A, Roskelley CD. (1999) Cell shape and integrin signaling regulate the differentiation state of mammary epithelial cells. Methods in Molecular Biology (Clifton, N.J.). 129: 271-83
Auersperg N, Pan J, Grove BD, et al. (1999) E-cadherin induces mesenchymal-to-epithelial transition in human ovarian surface epithelium Proceedings of the National Academy of Sciences of the United States of America. 96: 6249-6254
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