Andrew J. DeCastro, Ph.D.
Affiliations: | 2014 | Pharmacology and Toxicology | Dartmouth College, Hanover, NH, United States |
Area:
Molecular Biology, Oncology, PharmacologyGoogle:
"Andrew DeCastro"Parents
Sign in to add mentorJames DiRenzo | grad student | 2014 | Dartmouth | |
(The causes and consequences of regulation of Deltanp63alpha in mammary and breast cancer stem cells.) |
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Hu S, Danilov AV, Godek K, et al. (2015) CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110. Cancer Research. 75: 2029-38 |
Balboni AL, Cherukuri P, Ung M, et al. (2015) p53 and ΔNp63α Coregulate the Transcriptional and Cellular Response to TGFβ and BMP Signals. Molecular Cancer Research : McR. 13: 732-42 |
DeCastro AJ, Cherukuri P, Balboni A, et al. (2015) ΔNP63α transcriptionally activates chemokine receptor 4 (CXCR4) expression to regulate breast cancer stem cell activity and chemotaxis. Molecular Cancer Therapeutics. 14: 225-35 |
DeCastro AJ, DiRenzo J. (2014) miRNA function and modulation in stem cells and cancer stem cells Microrna Diagnostics and Therapeutics. 1 |
Hu S, Danilov AV, Godek KM, et al. (2014) Abstract 4549: CDK2 inhibition causes anaphase catastrophe through the centrosomal protein CP110 Cancer Research. 74: 4549-4549 |
DeCastro AJ, Dunphy KA, Hutchinson J, et al. (2013) MiR203 mediates subversion of stem cell properties during mammary epithelial differentiation via repression of ΔNP63α and promotes mesenchymal-to-epithelial transition. Cell Death & Disease. 4: e514 |
Balboni AL, Hutchinson JA, DeCastro AJ, et al. (2013) ΔNp63α-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells. Cancer Research. 73: 1020-30 |
Cherukuri P, DeCastro AJ, Balboni AL, et al. (2012) Phosphorylation of ΔNp63α via a novel TGFβ/ALK5 signaling mechanism mediates the anti-clonogenic effects of TGFβ. Plos One. 7: e50066 |
Kent S, Hutchinson J, Balboni A, et al. (2011) ΔNp63α promotes cellular quiescence via induction and activation of Notch3. Cell Cycle (Georgetown, Tex.). 10: 3111-8 |
Suh N, Reddy BS, DeCastro A, et al. (2011) Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/β-catenin/cyclin D1 signaling pathway in rats. Cancer Prevention Research (Philadelphia, Pa.). 4: 1895-902 |