Julian J. Lum, Ph.D.

Affiliations: 
2003 University of Ottawa, Ottawa, ON, Canada 
Area:
Immunology, Cell Biology, Molecular Biology
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"Julian Lum"

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Andrew Badley grad student 2003 University of Ottawa
 (Identification of TRAIL /Apo2L as a novel therapy targeting HIV reservoirs and the development of antiapoptotic peptides for protection from HIV induced cell death.)
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Publications

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Schlie K, Westerback A, DeVorkin L, et al. (2015) Survival of effector CD8+ T cells during influenza infection is dependent on autophagy Journal of Immunology. 194: 4277-4286
Amaravadi RK, Yu D, Lum JJ, et al. (2007) Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. The Journal of Clinical Investigation. 117: 326-36
Lum JJ, Bren G, McClure R, et al. (2005) Elimination of senescent neutrophils by TNF-related apoptosis-inducing [corrected] ligand. Journal of Immunology (Baltimore, Md. : 1950). 175: 1232-8
Lum JJ, Schnepple DJ, Badley AD. (2005) Acquired T-cell sensitivity to TRAIL mediated killing during HIV infection is regulated by CXCR4-gp120 interactions. Aids (London, England). 19: 1125-33
Lum JJ, Bren G, McClure R, et al. (2005) Elimination of senescent neutrophils by TNF-related apopotosis-inducing ligand The Journal of Immunology. 175: 3446.1-3446
Lum JJ, Schnepple DJ, Nie Z, et al. (2004) Differential effects of interleukin-7 and interleukin-15 on NK cell anti-human immunodeficiency virus activity. Journal of Virology. 78: 6033-42
Cooper CL, Phenix B, Mbisa G, et al. (2004) Antiretroviral therapy influences cellular susceptibility to apoptosis in vivo. Frontiers in Bioscience : a Journal and Virtual Library. 9: 338-41
Lum JJ, Badley AD. (2003) Resistance to apoptosis: mechanism for the development of HIV reservoirs. Current Hiv Research. 1: 261-74
Badley AD, Roumier T, Lum JJ, et al. (2003) Mitochondrion-mediated apoptosis in HIV-1 infection. Trends in Pharmacological Sciences. 24: 298-305
Lum JJ, Cohen OJ, Nie Z, et al. (2003) Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis. The Journal of Clinical Investigation. 111: 1547-54
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