Andrea Bredemeyer, Ph.D.

Affiliations: 
2006 Washington University, Saint Louis, St. Louis, MO 
Area:
Immunology, Cell Biology, Molecular Biology
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"Andrea Bredemeyer"

Parents

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Barry Sleckman grad student 2006 Washington University
 (ATM stabilizes DNA double strand break complexes during V(D)J recombination.)
Stephen J. Elledge post-doc 2009 Harvard Medical School (Chemistry Tree)
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Publications

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Chen BR, Quinet A, Byrum AK, et al. (2019) XLF and H2AX function in series to promote replication fork stability. The Journal of Cell Biology
Hung PJ, Johnson B, Chen BR, et al. (2018) MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining. Molecular Cell
Bredemeyer AL, Edwards BS, Haynes MK, et al. (2017) High-Throughput Screening Approach for Identifying Compounds That Inhibit Nonhomologous End Joining. Slas Discovery : Advancing Life Sciences R & D. 2472555217746324
Hung PJ, Chen BR, George R, et al. (2016) Deficiency of XLF and PAXX Prevents DNA Double-Strand Break Repair by Non-homologous End Joining in Lymphocytes. Cell Cycle (Georgetown, Tex.). 0
Brauer PM, Pessach IM, Clarke E, et al. (2016) Modeling altered T-cell development with human induced pluripotent stem cells from patients with RAG1 mutations and distinct immunological phenotypes. Blood
Bredemeyer AL, Sleckman BP. (2015) DNA damage responses: beyond double-strand break repair. Current Biology : Cb. 25: R45-6
Dorsett Y, Zhou Y, Tubbs AT, et al. (2014) HCoDES reveals chromosomal DNA end structures with single-nucleotide resolution. Molecular Cell. 56: 808-18
Tubbs AT, Dorsett Y, Chan E, et al. (2014) KAP-1 promotes resection of broken DNA ends not protected by γ-H2AX and 53BP1 in G₁-phase lymphocytes. Molecular and Cellular Biology. 34: 2811-21
Dose M, Emmanuel AO, Chaumeil J, et al. (2014) β-Catenin induces T-cell transformation by promoting genomic instability. Proceedings of the National Academy of Sciences of the United States of America. 111: 391-6
Lee BS, Gapud EJ, Zhang S, et al. (2013) Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination. Molecular and Cellular Biology. 33: 3568-79
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