Sarah A. Wernimont, Ph.D.

Affiliations: 
2011 University of Wisconsin, Madison, Madison, WI 
Area:
Immunology, Cell Biology
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"Sarah Wernimont"

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Anna Huttenlocker grad student 2011 UW Madison
 (Using integrins to fine tune CD4+ T cell responses: How the integrin regulatory proteins calpain, PIPKIgamma'90, talin and focal adhesion kinase work together to regulate CD4+ T cell activation.)
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Publications

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Mathis L, Wernimont S, Affentranger S, et al. (2013) Determinants of phosphatidylinositol-4-phosphate 5-kinase type Iγ90 uropod location in T-lymphocytes and its role in uropod formation. Peerj. 1: e131
Wiemer AJ, Wernimont SA, Cung TD, et al. (2013) The focal adhesion kinase inhibitor PF-562,271 impairs primary CD4+ T cell activation. Biochemical Pharmacology. 86: 770-81
Wiemer AJ, Wernimont S, Huttenlocher A. (2012) Live imaging of LFA-1-dependent T-cell motility and stop signals. Methods in Molecular Biology (Clifton, N.J.). 757: 191-204
Wernimont SA, Wiemer AJ, Bennin DA, et al. (2011) Contact-dependent T cell activation and T cell stopping require talin1. Journal of Immunology (Baltimore, Md. : 1950). 187: 6256-67
Wernimont SA, Legate KR, Simonson WT, et al. (2010) PIPKI gamma 90 negatively regulates LFA-1-mediated adhesion and activation in antigen-induced CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 185: 4714-23
Cortesio CL, Wernimont SA, Kastner DL, et al. (2010) Impaired podosome formation and invasive migration of macrophages from patients with a PSTPIP1 mutation and PAPA syndrome. Arthritis and Rheumatism. 62: 2556-8
Wernimont SA, Simonson WT, Greer PA, et al. (2010) Calpain 4 is not necessary for LFA-1-mediated function in CD4+ T cells. Plos One. 5: e10513
Schartner JM, Simonson WT, Wernimont SA, et al. (2009) Gene related to anergy in lymphocytes (GRAIL) expression in CD4+ T cells impairs actin cytoskeletal organization during T cell/antigen-presenting cell interactions. The Journal of Biological Chemistry. 284: 34674-81
Wang X, Chen X, Rodenkirch L, et al. (2008) Natural killer T-cell autoreactivity leads to a specialized activation state. Blood. 112: 4128-38
Welti R, Mui E, Sparks A, et al. (2007) Lipidomic analysis of Toxoplasma gondii reveals unusual polar lipids. Biochemistry. 46: 13882-90
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