Defu Zeng

Affiliations: 
Graduate School of Biological Sciences City of Hope's Irell & Manella Graduate School of Biomedical Sciences 
Area:
Physiology Biology, Molecular Biology, Cell Biology
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"Defu Zeng"
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Publications

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Li Q, Wang X, Song Q, et al. (2023) Donor T cell STAT3 deficiency enables tissue PD-L1-dependent prevention of graft-versus-host disease while preserving graft-versus-leukemia activity. The Journal of Clinical Investigation. 133
Huang Y, Wu X, Tang S, et al. (2023) Donor PD-L1 is required for organ transplant tolerance in MHC-mismatched mixed chimeras while PD-L1 and MHCII are not required for inducing chimerism. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Zhang Y, Song Q, Cassady K, et al. (2023) Blockade of trans PD-L1 interaction with CD80 augments antitumor immunity. Proceedings of the National Academy of Sciences of the United States of America. 120: e2205085120
Zhao X, Yang W, Yu T, et al. (2022) Th17 cell-derived amphiregulin promotes colitis-associated intestinal fibrosis through activation of mTOR and MEK in intestinal myofibroblasts. Gastroenterology
Kong X, Wu X, Wang B, et al. (2022) Trafficking between clonally related peripheral T helper cells and tissue-resident T helper cells in chronic GVHD. Blood
Song Q, Nasri U, Nakamura R, et al. (2022) Retention of Donor T Cells in Lymphohematopoietic Tissue and Augmentation of Tissue PD-L1 Protection for Prevention of GVHD While Preserving GVL Activity. Frontiers in Immunology. 13: 907673
Oh E, McCown EM, Ahn M, et al. (2021) Syntaxin 4 enrichment in β-cells prevents conversion to autoimmune diabetes in non-obese diabetic (NOD) mice. Diabetes
Song Q, Kong X, Martin PJ, et al. (2021) Murine Models Provide New Insights Into Pathogenesis of Chronic Graft--Host Disease in Humans. Frontiers in Immunology. 12: 700857
Song Q, Wang X, Wu X, et al. (2021) IL-22-dependent dysbiosis and mononuclear phagocyte depletion contribute to steroid-resistant gut graft-versus-host disease in mice. Nature Communications. 12: 805
Song Q, Wang X, Wu X, et al. (2021) Tolerogenic anti-IL-2 mAb prevents graft-versus-host disease while preserving strong graft-versus-leukemia activity. Blood
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