Michail Sitkovsky
Affiliations: | Biology | Northeastern University, Boston, MA, United States |
Area:
General Biology, Immunology, Cell BiologyGoogle:
"Michail Sitkovsky"Children
Sign in to add traineeRadhika G. Kini | grad student | 2012 | Northeastern University |
Meenakshi Subramanian | grad student | 2012 | Northeastern University |
Manasa M. Madasu | grad student | 2014 | Northeastern University |
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Publications
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Colombani T, Eggermont LJ, Hatfield SM, et al. (2021) Oxygen-Generating Cryogels Restore T Cell Mediated Cytotoxicity in Hypoxic Tumors. Advanced Functional Materials. 31 |
Hatfield SM, Sitkovsky MV. (2020) Antihypoxic oxygenation agents with respiratory hyperoxia to improve cancer immunotherapy. The Journal of Clinical Investigation |
Sitkovsky MV. (2020) Sufficient numbers of anti-tumor T cells is a condition of maximal efficacy of anti-hypoxia-A2-adenosinergic drugs during cancer immunotherapy. Current Opinion in Pharmacology. 53: 98-100 |
Sitkovsky MV. (2020) Lessons from the A2A Adenosine Receptor Antagonist-Enabled Tumor Regression and Survival in Patients with Treatment-Refractory Renal Cell Cancer. Cancer Discovery. 10: 16-19 |
Hatfield S, Veszeleiova K, Steingold J, et al. (2019) Mechanistic Justifications of Systemic Therapeutic Oxygenation of Tumors to Weaken the Hypoxia Inducible Factor 1α-Mediated Immunosuppression. Advances in Experimental Medicine and Biology. 1136: 113-121 |
Kjaergaard J, Hatfield S, Jones G, et al. (2018) A Adenosine Receptor Gene Deletion or Synthetic A Antagonist Liberate Tumor-Reactive CD8 T Cells from Tumor-Induced Immunosuppression. Journal of Immunology (Baltimore, Md. : 1950) |
Yuan G, Jankins TC, Patrick CG, et al. (2017) Fluorinated Adenosine A2A Receptor Antagonists Inspired by Preladenant as Potential Cancer Immunotherapeutics. International Journal of Medicinal Chemistry. 2017: 4852537 |
Sethumadhavan S, Silva M, Philbrook P, et al. (2017) Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells. Plos One. 12: e0187314 |
Abbott RK, Silva M, Labuda J, et al. (2016) The GS protein coupled A2a adenosine receptor controls T cell help in the germinal center. The Journal of Biological Chemistry |
Cronstein BN, Sitkovsky M. (2016) Adenosine and adenosine receptors in the pathogenesis and treatment of rheumatic diseases. Nature Reviews. Rheumatology |