Michail Sitkovsky

Affiliations: 
Biology Northeastern University, Boston, MA, United States 
Area:
General Biology, Immunology, Cell Biology
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"Michail Sitkovsky"
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Publications

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Colombani T, Eggermont LJ, Hatfield SM, et al. (2021) Oxygen-Generating Cryogels Restore T Cell Mediated Cytotoxicity in Hypoxic Tumors. Advanced Functional Materials. 31
Hatfield SM, Sitkovsky MV. (2020) Antihypoxic oxygenation agents with respiratory hyperoxia to improve cancer immunotherapy. The Journal of Clinical Investigation
Sitkovsky MV. (2020) Sufficient numbers of anti-tumor T cells is a condition of maximal efficacy of anti-hypoxia-A2-adenosinergic drugs during cancer immunotherapy. Current Opinion in Pharmacology. 53: 98-100
Sitkovsky MV. (2020) Lessons from the A2A Adenosine Receptor Antagonist-Enabled Tumor Regression and Survival in Patients with Treatment-Refractory Renal Cell Cancer. Cancer Discovery. 10: 16-19
Hatfield S, Veszeleiova K, Steingold J, et al. (2019) Mechanistic Justifications of Systemic Therapeutic Oxygenation of Tumors to Weaken the Hypoxia Inducible Factor 1α-Mediated Immunosuppression. Advances in Experimental Medicine and Biology. 1136: 113-121
Kjaergaard J, Hatfield S, Jones G, et al. (2018) A Adenosine Receptor Gene Deletion or Synthetic A Antagonist Liberate Tumor-Reactive CD8 T Cells from Tumor-Induced Immunosuppression. Journal of Immunology (Baltimore, Md. : 1950)
Yuan G, Jankins TC, Patrick CG, et al. (2017) Fluorinated Adenosine A2A Receptor Antagonists Inspired by Preladenant as Potential Cancer Immunotherapeutics. International Journal of Medicinal Chemistry. 2017: 4852537
Sethumadhavan S, Silva M, Philbrook P, et al. (2017) Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells. Plos One. 12: e0187314
Abbott RK, Silva M, Labuda J, et al. (2016) The GS protein coupled A2a adenosine receptor controls T cell help in the germinal center. The Journal of Biological Chemistry
Cronstein BN, Sitkovsky M. (2016) Adenosine and adenosine receptors in the pathogenesis and treatment of rheumatic diseases. Nature Reviews. Rheumatology
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