Michael Kluppel
Affiliations: | Integrated Graduate Program in the Life Sciences | Northwestern University, Evanston, IL |
Area:
Cell Biology, Molecular Biology, OncologyGoogle:
"Michael Kluppel"
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Publications
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| Willis CM, Klüppel M. (2014) Chondroitin sulfate-E is a negative regulator of a pro-tumorigenic Wnt/beta-catenin-Collagen 1 axis in breast cancer cells. Plos One. 9: e103966 |
| Prinz RD, Willis CM, van Kuppevelt TH, et al. (2014) Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/β-catenin signaling. Plos One. 9: e92381 |
| Kluppel M. (2014) The extracellular matrix in stem cell commitment: Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/beta-catenin signaling Journal of Cell Science and Therapy |
| Willis CM, Klüppel M. (2012) Inhibition by chondroitin sulfate E can specify functional Wnt/β-catenin signaling thresholds in NIH3T3 fibroblasts. The Journal of Biological Chemistry. 287: 37042-56 |
| Klüppel M, Samavarchi-Tehrani P, Liu K, et al. (2012) C4ST-1/CHST11-controlled chondroitin sulfation interferes with oncogenic HRAS signaling in Costello syndrome. European Journal of Human Genetics : Ejhg. 20: 870-7 |
| Willis CM, Klüppel M. (2012) Abstract 3250: Chondroitin sulfate-mediated regulation of Wnt/β-catenin signaling in breast cancer Cancer Research. 72: 3250-3250 |
| Prinz RD, Willis CM, Viloria-Petit A, et al. (2011) Elimination of breast tumor-associated chondroitin sulfate promotes metastasis. Genetics and Molecular Research : Gmr. 10: 3901-13 |
| Klüppel M. (2011) Efficient secretion of biologically active Chondroitinase ABC from mammalian cells in the absence of an N-terminal signal peptide. Molecular and Cellular Biochemistry. 351: 1-11 |
| Klüppel M. (2010) The roles of chondroitin-4-sulfotransferase-1 in development and disease. Progress in Molecular Biology and Translational Science. 93: 113-32 |
| Willis CM, Wrana JL, Klüppel M. (2009) Identification and characterization of TGFbeta-dependent and -independent cis-regulatory modules in the C4ST-1/CHST11 locus. Genetics and Molecular Research : Gmr. 8: 1331-43 |