Morris F. Manolson

Affiliations: 
Dentistry University of Toronto, Toronto, ON, Canada 
Area:
Molecular Biology, Cell Biology, Oncology
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"Morris Manolson"
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Publications

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Chu A, Yao Y, Glibowicka M, et al. (2024) The Human Mutation K237_V238del in a Putative Lipid Binding Motif within the V-ATPase a2 Isoform Suggests a Molecular Mechanism Underlying Cutis Laxa. International Journal of Molecular Sciences. 25
Oot RA, Yao Y, Manolson MF, et al. (2021) Purification of active human vacuolar ATPase in native lipid-containing nanodiscs. The Journal of Biological Chemistry. 100964
Chu A, Zirngibl RA, Manolson MF. (2021) The V-ATPase 3 Subunit: Structure, Function and Therapeutic Potential of an Essential Biomolecule in Osteoclastic Bone Resorption. International Journal of Molecular Sciences. 22
Zirngibl RA, Wang A, Yao Y, et al. (2019) Novel c.G630A TCIRG1 mutation causes aberrant splicing resulting in an unusually mild form of autosomal recessive osteopetrosis. Journal of Cellular Biochemistry
Esmail S, Kartner N, Yao Y, et al. (2018) Molecular mechanisms of cutis laxa and distal renal tubular acidosis-causing mutations in V-ATPase a subunits, ATP6V0A2 and ATP6V0A4. The Journal of Biological Chemistry
Esmail S, Kartner N, Yao Y, et al. (2017) N-linked Glycosylation of a Subunit Isoforms is Critical for Vertebrate Vacuolar H(+) -ATPase (V-ATPase) Biosynthesis. Journal of Cellular Biochemistry
Esmail S, Yao Y, Kartner N, et al. (2016) N-Linked Glycosylation Is Required for Vacuolar H(+) -ATPase (V-ATPase) a4 Subunit Stability, Assembly, and Cell Surface Expression. Journal of Cellular Biochemistry
Bernard D, Gebbia M, Prabha S, et al. (2015) Select microtubule inhibitors increase lysosome acidity and promote lysosomal disruption in acute myeloid leukemia (AML) cells. Apoptosis : An International Journal On Programmed Cell Death. 20: 948-59
Ochotny N, Voronov I, Owen C, et al. (2013) The R740S mutation in the V-ATPase a3 subunit results in osteoclast apoptosis and defective early-stage autophagy. Journal of Cellular Biochemistry. 114: 2823-33
Ramachandran N, Munteanu I, Wang P, et al. (2013) VMA21 deficiency prevents vacuolar ATPase assembly and causes autophagic vacuolar myopathy. Acta Neuropathologica. 125: 439-57
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