Catherine Freudenreich

Affiliations: 
Biology Tufts University, Boston 
Area:
Molecular Biology
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"Catherine Freudenreich"

Children

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Haihua Zhang grad student 2007 Tufts
Ranjith P. Anand grad student 2010 Tufts
Jiahui Yang grad student 2010 Tufts
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Publications

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Brown RE, Coxon M, Larsen B, et al. (2025) APOBEC3A deaminates CTG hairpin loops to promote fragility and instability of expanded CAG/CTG repeats. Proceedings of the National Academy of Sciences of the United States of America. 122: e2408179122
Das M, Hile SE, Brewster J, et al. (2024) DNA polymerase zeta can efficiently replicate structures formed by AT/TA repeat sequences and prevent their deletion. Nucleic Acids Research
Mirceta M, Schmidt MHM, Shum N, et al. (2024) repeat expansion creates the unstable folate-sensitive fragile site FRA9A. Nar Molecular Medicine. 1: ugae019
Mirceta M, Schmidt MHM, Shum N, et al. (2024) expansion creates the unstable folate-sensitive fragile site FRA9A. Biorxiv : the Preprint Server For Biology
Maclay T, Whalen J, Johnson M, et al. (2024) The DNA Damage Checkpoint Targets the Kinetochore for Relocation of Collapsed Forks to the Periphery. Biorxiv : the Preprint Server For Biology
Polleys EJ, Del Priore I, Haber JE, et al. (2023) Structure-forming CAG/CTG repeats interfere with gap repair to cause repeat expansions and chromosome breaks. Nature Communications. 14: 2469
Wang ET, Freudenreich CH, Gromak N, et al. (2023) What repeat expansion disorders can teach us about the Central Dogma. Molecular Cell. 83: 324-329
Brown RE, Su XA, Fair S, et al. (2022) The RNA export and RNA decay complexes THO and TRAMP prevent transcription-replication conflicts, DNA breaks, and CAG repeat contractions. Plos Biology. 20: e3001940
Spivakovsky-Gonzalez E, Polleys EJ, Masnovo C, et al. (2021) Rad9-mediated checkpoint activation is responsible for elevated expansions of GAA repeats in CST-deficient yeast. Genetics. 219
Gold MA, Whalen JM, Freon K, et al. (2021) Restarted replication forks are error-prone and cause CAG repeat expansions and contractions. Plos Genetics. 17: e1009863
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