William T. Silkworth, Ph.D.

Affiliations: 
2012 Virginia Polytechnic Institute and State University, Blacksburg, VA, United States 
Area:
Cell Biology
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"William Silkworth"

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Daniela Cimini grad student 2012 Virginia Tech
 (The Effect of Spindle Geometry on the Establishment of Merotelic Kinetochore Attachment and Chromosome Mis-segregation.)
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Publications

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Pampalona J, Roscioli E, Silkworth WT, et al. (2016) Chromosome Bridges Maintain Kinetochore-Microtubule Attachment throughout Mitosis and Rarely Break during Anaphase. Plos One. 11: e0147420
Bakhoum SF, Silkworth WT, Nardi IK, et al. (2014) The mitotic origin of chromosomal instability. Current Biology : Cb. 24: R148-9
Silkworth WT, Cimini D. (2012) Transient defects of mitotic spindle geometry and chromosome segregation errors. Cell Division. 7: 19
Silkworth WT, Nardi IK, Paul R, et al. (2012) Timing of centrosome separation is important for accurate chromosome segregation. Molecular Biology of the Cell. 23: 401-11
Creekmore AL, Silkworth WT, Cimini D, et al. (2011) Changes in gene expression and cellular architecture in an ovarian cancer progression model. Plos One. 6: e17676
Paul R, Wollman R, Silkworth WT, et al. (2009) Computer simulations predict that chromosome movements and rotations accelerate mitotic spindle assembly without compromising accuracy. Proceedings of the National Academy of Sciences of the United States of America. 106: 15708-13
Silkworth WT, Nardi IK, Scholl LM, et al. (2009) Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cells. Plos One. 4: e6564
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