Michael A. Paley, Ph.D.

Affiliations: 
2012 Immunology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Immunology, Cell Biology, Virology Biology
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"Michael Paley"

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E John Wherry grad student 2012 Penn
 (Transcriptional control and population dynamics of antiviral CD8+ T cell responses.)
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Publications

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Paley MA, Yang X, Hassman LM, et al. (2024) Mucosal signatures of pathogenic T cells in HLA-B*27+ anterior uveitis and axial spondyloarthritis. Jci Insight
Paley MA, Baker BJ, Dunham SR, et al. (2022) The CSF in neurosarcoidosis contains consistent clonal expansion of CD8 T cells, but not CD4 T cells. Journal of Neuroimmunology. 367: 577860
Johnnidis JB, Muroyama Y, Ngiow SF, et al. (2021) Inhibitory signaling sustains a distinct early memory CD8 T cell precursor that is resistant to DNA damage. Science Immunology. 6
Lauron EJ, Yang L, Harvey IB, et al. (2018) Viral MHCI inhibition evades tissue-resident memory T cell formation and responses. The Journal of Experimental Medicine
Bengsch B, Johnson AL, Kurachi M, et al. (2016) Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8(+) T Cell Exhaustion. Immunity
Barnett BE, Staupe RP, Odorizzi PM, et al. (2016) Cutting Edge: B Cell-Intrinsic T-bet Expression Is Required To Control Chronic Viral Infection. Journal of Immunology (Baltimore, Md. : 1950)
Odorizzi PM, Pauken KE, Paley MA, et al. (2015) Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cells. The Journal of Experimental Medicine. 212: 1125-37
Paley MA, Gordon SM, Bikoff EK, et al. (2013) Technical Advance: Fluorescent reporter reveals insights into eomesodermin biology in cytotoxic lymphocytes. Journal of Leukocyte Biology. 93: 307-15
Paley MA, Kroy DC, Odorizzi PM, et al. (2012) Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection. Science (New York, N.Y.). 338: 1220-5
Doering TA, Crawford A, Angelosanto JM, et al. (2012) Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory. Immunity. 37: 1130-44
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