Christina Loh, Ph.D.

Affiliations: 
2011 Immunology University of Toronto, Toronto, ON, Canada 
Area:
Immunology
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"Christina Loh"

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Joan Wither grad student 2011 University of Toronto
 (Identification of Genetic Loci that Contribute to the Immunopathogenesis of Systemic Lupus Erythematosus using Congenic Mouse Strains.)
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Publications

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Chang NH, Manion KP, Loh C, et al. (2017) Multiple tolerance defects contribute to the breach of B cell tolerance in New Zealand Black chromosome 1 congenic mice. Plos One. 12: e0179506
Baglaenko Y, Manion KP, Chang NH, et al. (2016) IL-10 Production Is Critical for Sustaining the Expansion of CD5+ B and NKT Cells and Restraining Autoantibody Production in Congenic Lupus-Prone Mice. Plos One. 11: e0150515
Schaffert SA, Loh C, Wang S, et al. (2015) mir-181a-1/b-1 Modulates Tolerance through Opposing Activities in Selection and Peripheral T Cell Function. Journal of Immunology (Baltimore, Md. : 1950)
Baglaenko Y, Manion KP, Chang NH, et al. (2015) Suppression of autoimmunity by CD5(+) IL-10-producing B cells in lupus-prone mice. Genes and Immunity. 16: 311-20
Pau E, Loh C, Minty GE, et al. (2013) Identification of a lupus-susceptibility locus leading to impaired clearance of apoptotic debris on New Zealand Black chromosome 13. Genes and Immunity. 14: 154-61
Pau E, Cheung YH, Loh C, et al. (2012) TLR tolerance reduces IFN-alpha production despite plasmacytoid dendritic cell expansion and anti-nuclear antibodies in NZB bicongenic mice. Plos One. 7: e36761
Loh C, Pau E, Lajoie G, et al. (2011) Epistatic suppression of fatal autoimmunity in New Zealand black bicongenic mice. Journal of Immunology (Baltimore, Md. : 1950). 186: 5845-53
Pau E, Chang NH, Loh C, et al. (2011) Abrogation of pathogenic IgG autoantibody production in CD40L gene-deleted lupus-prone New Zealand Black mice. Clinical Immunology (Orlando, Fla.). 139: 215-27
Loh C, Pau E, Chang NH, et al. (2011) An intrinsic B-cell defect supports autoimmunity in New Zealand black chromosome 13 congenic mice. European Journal of Immunology. 41: 527-36
Chang NH, Cheung YH, Loh C, et al. (2010) B Cell activating factor (BAFF) and T cells cooperate to breach B cell tolerance in lupus-prone New Zealand Black (NZB) mice Plos One. 5
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