Yen-Shou Lin, Ph.D.

Affiliations: 
2000 Boston University, Boston, MA, United States 
Area:
Animal Physiology Biology
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"Yen-Shou Lin"

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Neil Ruderman grad student 2000 Boston University
 (Impaired signaling in skeletal muscle in insulin -resistant states.)
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Publications

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Yao CA, Ortiz-Vega S, Sun YY, et al. (2017) Association of mSin1 with mTORC2 Ras and Akt reveals a crucial domain on mSin1 involved in Akt phosphorylation. Oncotarget. 8: 63392-63404
Chen WY, Lin CL, Chuang JH, et al. (2017) Heterogeneous nuclear ribonucleoprotein M associates with mTORC2 and regulates muscle differentiation. Scientific Reports. 7: 41159
Chuang JH, Tung LC, Lin Y. (2015) Neural differentiation from embryonic stem cells in vitro: An overview of the signaling pathways. World Journal of Stem Cells. 7: 437-47
Chen CY, Chiu FY, Lin Y, et al. (2015) Chemical constituents analysis and antidiabetic activity validation of four fern species from Taiwan. International Journal of Molecular Sciences. 16: 2497-516
Hsieh CT, Chuang JH, Yang WC, et al. (2014) Ceramide inhibits insulin-stimulated Akt phosphorylation through activation of Rheb/mTORC1/S6K signaling in skeletal muscle. Cellular Signalling. 26: 1400-8
Chuang JH, Kao YJ, Ruderman NB, et al. (2011) Optimal concentrations of N-decanoyl-N-methylglucamine and sodium dodecyl sulfate allow the extraction and analysis of membrane proteins. Analytical Biochemistry. 418: 298-300
Avruch J, Long X, Lin Y, et al. (2010) Regulation of TOR complex 1 by amino acids through small GTPases Enzymes. 27: 57-73
Avruch J, Long X, Lin Y, et al. (2009) Activation of mTORC1 in two steps: Rheb-GTP activation of catalytic function and increased binding of substrates to raptor. Biochemical Society Transactions. 37: 223-6
Hagan GN, Lin Y, Magnuson MA, et al. (2008) A Rictor-Myo1c complex participates in dynamic cortical actin events in 3T3-L1 adipocytes. Molecular and Cellular Biology. 28: 4215-26
Long X, Lin Y, Ortiz-Vega S, et al. (2007) The Rheb switch 2 segment is critical for signaling to target of rapamycin complex 1. The Journal of Biological Chemistry. 282: 18542-51
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