Shruti Lal, Ph.D.

Affiliations: 
2011 Genetics, Genomics and Bioinformatics University of California, Riverside, Riverside, CA, United States 
Area:
Molecular Biology, Genetics, Bioinformatics Biology
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"Shruti Lal"

Parents

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Harley Smith grad student 2011 UC Riverside
 (Integration of Molecular Networks in the Shoot Apical Meristem that Controls Floral Specification in Arabidopsis thaliana.)
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Publications

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Zarei M, Lal S, Vaziri-Gohar A, et al. (2018) RNA-binding Protein HuR Regulates Both Mutant and Wild-type IDH1 in IDH1-mutated Cancer. Molecular Cancer Research : McR
Chand SN, Zarei M, Schiewer MJ, et al. (2017) Post-transcriptional regulation of PARG mRNA by HuR facilitates DNA repair and resistance to PARP inhibitors. Cancer Research
Zarei M, Lal S, Parker SJ, et al. (2017) Posttranscriptional upregulation of IDH1 by HuR establishes a powerful survival phenotype in pancreatic cancer cells. Cancer Research
Lal S, Cheung EC, Zarei M, et al. (2017) CRISPR Knockout of the HuR Gene Causes a Xenograft Lethal Phenotype. Molecular Cancer Research : McR
Lal S, Zarei M, Chand SN, et al. (2016) WEE1 inhibition in pancreatic cancer cells is dependent on DNA repair status in a context dependent manner. Scientific Reports. 6: 33323
Cheung E, Lal S, Zarei M, et al. (2016) Abstract 2854: CRISPR knockout of HuR in pancreatic cancer cells causes a xenograft lethal phenotype Cancer Research. 76: 2854-2854
Zarei M, Lal S, Mambelli-Lisboa NC, et al. (2016) Abstract 1847: The mRNA-binding protein HuR, regulates mutant and wild type IDH1 expression in IDH1-mutated cancer Cancer Research. 76: 1847-1847
Cozzitorto JA, Jimbo M, Chand S, et al. (2015) Studying RNA-binding protein interactions with target mRNAs in eukaryotic cells: native ribonucleoprotein immunoprecipitation (RIP) assays. Methods in Molecular Biology (Clifton, N.J.). 1262: 239-46
Tholey RM, Lal S, Jimbo M, et al. (2015) MUC1 Promoter-Driven DTA as a Targeted Therapeutic Strategy against Pancreatic Cancer. Molecular Cancer Research : McR. 13: 439-48
Lal S, Chand SN, Dylgjeri E, et al. (2015) Abstract 1656: MK-1775 (WEE1 inhibition) lacks efficacy against DNA repair deficient pancreatic cancer cells Cancer Research. 75: 1656-1656
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