Jennifer M. Eccleston, Ph.D.

Affiliations: 
2010 Immunology Sackler School of Graduate Biomedical Sciences (Tufts University) 
Area:
Immunology, Genetics, Molecular Biology
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"Jennifer Eccleston"

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Erik Selsing grad student 2010 Sackler School of Graduate Biomedical Sciences (Tufts University)
 (Class switch recombination and DNA repair.)
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Publications

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Shansab M, Eccleston JM, Selsing E. (2011) Translocation of an antibody transgene requires AID and occurs by interchromosomal switching to all switch regions except the mu switch region. European Journal of Immunology. 41: 1456-64
Basu U, Meng FL, Keim C, et al. (2011) The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates. Cell. 144: 353-63
Eccleston J, Yan C, Yuan K, et al. (2011) Mismatch repair proteins MSH2, MLH1, and EXO1 are important for class-switch recombination events occurring in B cells that lack nonhomologous end joining. Journal of Immunology (Baltimore, Md. : 1950). 186: 2336-43
Eccleston J, Schrader CE, Yuan K, et al. (2009) Class switch recombination efficiency and junction microhomology patterns in Msh2-, Mlh1-, and Exo1-deficient mice depend on the presence of mu switch region tandem repeats. Journal of Immunology (Baltimore, Md. : 1950). 183: 1222-8
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