Noam Bourquard, Ph.D.

Affiliations: 
2011 University of California, Los Angeles, Los Angeles, CA 
Area:
Molecular Biology, Physiology Biology
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"Noam Bourquard"

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Guatam Chaudhuri grad student 2011 UCLA
 (Studies on the Physiological Role of Paraoxonase 2 in Inflammatory Diseases.)
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Publications

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Parsanejad M, Bourquard N, Qu D, et al. (2014) DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress. Plos One. 9: e106601
Devarajan A, Bourquard N, Grijalva VR, et al. (2013) Role of PON2 in innate immune response in an acute infection model. Molecular Genetics and Metabolism. 110: 362-70
Devarajan A, Grijalva VR, Bourquard N, et al. (2012) Macrophage paraoxonase 2 regulates calcium homeostasis and cell survival under endoplasmic reticulum stress conditions and is sufficient to prevent the development of aggravated atherosclerosis in paraoxonase 2 deficiency/apoE-/- mice on a Western diet. Molecular Genetics and Metabolism. 107: 416-27
Reddy ST, Devarajan A, Bourquard N. (2012) Paraoxonase 2 Deficiency Leads to Impaired Mitochondrial Function and Increased Susceptibility to Insulin Resistant in Male Mice Free Radical Biology and Medicine. 53: S94
Kim JB, Xia YR, Romanoski CE, et al. (2011) Paraoxonase-2 modulates stress response of endothelial cells to oxidized phospholipids and a bacterial quorum-sensing molecule. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2624-33
Bourquard N, Ng CJ, Reddy ST. (2011) Impaired hepatic insulin signalling in PON2-deficient mice: a novel role for the PON2/apoE axis on the macrophage inflammatory response. The Biochemical Journal. 436: 91-100
Devarajan A, Bourquard N, Hama S, et al. (2011) Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis. Antioxidants & Redox Signaling. 14: 341-51
Devarajan A, Devarajan A, Grijalva V, et al. (2011) Coupling Mitochondrial Dysfunction To Endoplasmic Reticulum Stress Response: a Molecular Mechanism Leading To Atherosclerosis in Paraoxonase 2 Deficient Mice Free Radical Biology and Medicine. 51: S39
Kim WK, Meliton V, Bourquard N, et al. (2010) Hedgehog signaling and osteogenic differentiation in multipotent bone marrow stromal cells are inhibited by oxidative stress. Journal of Cellular Biochemistry. 111: 1199-209
Reddy ST, Devarajan A, Bourquard N, et al. (2008) Is it just paraoxonase 1 or are other members of the paraoxonase gene family implicated in atherosclerosis? Current Opinion in Lipidology. 19: 405-8
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