Siu P. Ngok, Ph.D.
Affiliations: | 2012 | Molecular Pharmacology and Experimental Therapeutics | College of Medicine - Mayo Clinic |
Area:
Cell Biology, Molecular BiologyGoogle:
"Siu Ngok"Parents
Sign in to add mentor| Panagiotis Anastasiadis | grad student | 2012 | College of Medicine - Mayo Clinic | |
| (Regulation and function of the RhoGEF Plekhg5 in intercellular junction formation and monolayer integrity.) | ||||
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Publications
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| Kourtidis A, Ngok SP, Pulimeno P, et al. (2015) Distinct E-cadherin-based complexes regulate cell behaviour through miRNA processing or Src and p120 catenin activity. Nature Cell Biology. 17: 1145-57 |
| Ngok SP, Lin WH, Anastasiadis PZ. (2014) Establishment of epithelial polarity--GEF who's minding the GAP? Journal of Cell Science. 127: 3205-15 |
| Ngok SP, Anastasiadis PZ. (2013) Rho GEFs in endothelial junctions: Effector selectivity and signaling integration determine junctional response. Tissue Barriers. 1: e27132 |
| Dachsel JC, Ngok SP, Lewis-Tuffin LJ, et al. (2013) The Rho guanine nucleotide exchange factor Syx regulates the balance of dia and ROCK activities to promote polarized-cancer-cell migration. Molecular and Cellular Biology. 33: 4909-18 |
| Ngok SP, Geyer R, Kourtidis A, et al. (2013) TEM4 is a junctional Rho GEF required for cell-cell adhesion, monolayer integrity and barrier function. Journal of Cell Science. 126: 3271-7 |
| Kourtidis A, Ngok SP, Anastasiadis PZ. (2013) p120 catenin: an essential regulator of cadherin stability, adhesion-induced signaling, and cancer progression. Progress in Molecular Biology and Translational Science. 116: 409-32 |
| Ngok SP, Geyer R, Kourtidis A, et al. (2013) Phosphorylation-mediated 14-3-3 protein binding regulates the function of the rho-specific guanine nucleotide exchange factor (RhoGEF) Syx. The Journal of Biological Chemistry. 288: 6640-50 |
| Ngok SP, Geyer R, Liu M, et al. (2012) VEGF and Angiopoietin-1 exert opposing effects on cell junctions by regulating the Rho GEF Syx. The Journal of Cell Biology. 199: 1103-15 |