Spencer W. Luebben, Ph.D.

Affiliations: 
2014 Molecular, Cellular, Developmental Biology and Genetics University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Genetics, Molecular Biology, Cell Biology
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"Spencer Luebben"

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Naoko Shima grad student 2014 UMN
 (The Fanconi anemia pathway and HELQ work alongside dormant replication origins to suppress replication-associated genome instability.)
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Publications

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Luebben SW, Shima N, Kawabata T. (2014) Methods for the detection of genome instability derived from replication stress in primary mouse embryonic fibroblasts. Methods in Molecular Biology (Clifton, N.J.). 1194: 341-52
Luebben SW, Kawabata T, Johnson CS, et al. (2014) A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression. Nucleic Acids Research. 42: 5605-15
Luebben SW, Kawabata T, Akre MK, et al. (2013) Helq acts in parallel to Fancc to suppress replication-associated genome instability. Nucleic Acids Research. 41: 10283-97
Kawabata T, Yamaguchi S, Buske T, et al. (2011) A reduction of licensed origins reveals strain-specific replication dynamics in mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 22: 506-17
Kawabata T, Luebben SW, Yamaguchi S, et al. (2011) Stalled fork rescue via dormant replication origins in unchallenged S phase promotes proper chromosome segregation and tumor suppression. Molecular Cell. 41: 543-53
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