Benford Mafuvadze, Ph.D.

Affiliations: 
2012 Biomedical Sciences University of Missouri - Columbia, Columbia, MO, United States 
Area:
Oncology, Endocrinology Biology, Molecular Biology
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"Benford Mafuvadze"

Parents

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Salman M. Hyder grad student 2012 University of Missouri - Columbia
 (Apigenin: Chemopreventive and chemotherapeutic potential for progestin-dependent breast cancer.)
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Publications

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Liang Y, Mafuvadze B, Besch-Williford C, et al. (2018) A combination of p53-activating APR-246 and phosphatidylserine-targeting antibody potently inhibits tumor development in hormone-dependent mutant p53-expressing breast cancer xenografts. Breast Cancer (Dove Medical Press). 10: 53-67
Goyette S, Liang Y, Mafuvadze B, et al. (2017) Natural and synthetic progestins enrich cancer stem cell-like cells in hormone-responsive human breast cancer cell populations in vitro. Breast Cancer (Dove Medical Press). 9: 347-357
Liang Y, Mafuvadze B, Aebi JD, et al. (2016) Cholesterol biosynthesis inhibitor RO 48-8071 suppresses growth of hormone-dependent and castration-resistant prostate cancer cells. Oncotargets and Therapy. 9: 3223-32
Cook MT, Mafuvadze B, Besch-Williford C, et al. (2016) Luteolin suppresses development of medroxyprogesterone acetate-accelerated 7,12-dimethylbenz(a)anthracene-induced mammary tumors in Sprague-Dawley rats. Oncology Reports. 35: 825-32
Goyette S, Mafuvadze B, Cook MT, et al. (2016) Abstract 1807: Progestin enrichment of the cancer stem cell-like pool provides novel therapeutic targets for hormone-dependent human breast cancer Cancer Research. 76: 1807-1807
Cook MT, Liang Y, Besch-Williford C, et al. (2015) Luteolin inhibits progestin-dependent angiogenesis, stem cell-like characteristics, and growth of human breast cancer xenografts. Springerplus. 4: 444
Liang Y, Mafuvadze B, Zou X, et al. (2015) Abstract 5422: Inhibition of oxidosqualene cyclase blocks proliferation and survival of prostate cancer cells Cancer Research. 75: 5422-5422
Goyette S, Mafuvadze B, Cook MT, et al. (2015) Abstract 1867: Enrichment of CD44highstem-cell-like cells as a possible mechanism of progestin-dependent progression of human breast cancer Cancer Research. 75: 1867-1867
Mafuvadze B, Liang Y, Hyder SM. (2014) Cholesterol synthesis inhibitor RO 48-8071 suppresses transcriptional activity of human estrogen and androgen receptor. Oncology Reports. 32: 1727-33
Liang Y, Besch-Williford C, Aebi JD, et al. (2014) Cholesterol biosynthesis inhibitors as potent novel anti-cancer agents: suppression of hormone-dependent breast cancer by the oxidosqualene cyclase inhibitor RO 48-8071. Breast Cancer Research and Treatment. 146: 51-62
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