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Stephen L. Lessnick, MD, PhD

Affiliations: 
2004-2015 Pediatrics, Oncological Sciences University of Utah, Salt Lake City, UT 
 2015- Department of Pediatrics and Center for Childhood Cancer and Blood Diseases The Ohio State University and Nationwide Children's Hospital 
Area:
Molecular Biology, Oncology, Human Development, Genetics, Pathology
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"Stephen Lessnick"
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Parents

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Christopher T. Denny grad student 1992-1994 UCLA Medical School
Todd Golub post-doc 1999-2003 Dana Farber Cancer Institute, Harvard Medical School

Children

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Leah Owen grad student University of Utah
Savita Sankar grad student 2013 University of Utah
Elizabeth C. Toomey grad student 2013 University of Utah

Collaborators

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BETA: Related publications

Publications

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Showpnil IA, Selich-Anderson J, Taslim C, et al. (2022) EWS/FLI mediated reprogramming of 3D chromatin promotes an altered transcriptional state in Ewing sarcoma. Nucleic Acids Research
Shulman DS, Whittle SB, Surdez D, et al. (2022) An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma. Npj Precision Oncology. 6: 65
Boone MA, Taslim C, Crow JC, et al. (2021) Identification of a novel FUS/ETV4 fusion and comparative analysis with other Ewing sarcoma fusion proteins. Molecular Cancer Research : McR
Boone MA, Taslim C, Crow JC, et al. (2021) The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma. Oncogene
Theisen ER, Selich-Anderson J, Miller KR, et al. (2020) Chromatin profiling reveals relocalization of lysine-specific demethylase 1 by an oncogenic fusion protein. Epigenetics. 1-20
Showpnil IA, Miller KR, Taslim C, et al. (2020) Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis. Journal of Visualized Experiments : Jove
Luo W, Xu C, Phillips S, et al. (2020) Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma. Oncotarget. 11: 1691-1704
Patel PO, Pishas KI, Taslim C, et al. (2019) Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma. Oncotarget. 10: 3865-3878
Theisen ER, Miller KR, Showpnil IA, et al. (2019) Transcriptomic analysis functionally maps the intrinsically disordered domain of EWS/FLI and reveals novel transcriptional dependencies for oncogenesis. Genes & Cancer. 10: 21-38
Harlow ML, Chasse MH, Boguslawski EA, et al. (2019) Trabectedin Inhibits EWS-FLI1 and Evicts SWI/SNF from Chromatin in a Schedule Dependent Manner. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
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