April D. Lake, Ph.D.
Affiliations: | 2013 | Pharmacology & Toxicology | University of Arizona, Tucson, AZ |
Area:
Toxicology, Pharmacology, Molecular Biology, PathologyGoogle:
"April Lake"Parents
Sign in to add mentor| Nathan J. Cherrington | grad student | 2013 | University of Arizona | |
| (Hepatic stress response mechanisms in progressive human nonalcoholic fatty liver disease.) | ||||
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Publications
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| Lake AD, Hardwick RN, Leamon CP, et al. (2019) Folate receptor-beta expression as a diagnostic target in human & rodent nonalcoholic steatohepatitis. Toxicology and Applied Pharmacology |
| Han J, Dzierlenga AL, Lu Z, et al. (2017) Metabolomic profiling distinction of human nonalcoholic fatty liver disease progression from a common rat model. Obesity (Silver Spring, Md.) |
| Clarke JD, Novak P, Lake AD, et al. (2017) Impaired N-linked Glycosylation of Uptake and Efflux Transporters in Human Nonalcoholic Fatty Liver Disease. Liver International : Official Journal of the International Association For the Study of the Liver |
| Lake AD, Chaput AL, Novak P, et al. (2016) Transcription factor binding site enrichment analysis predicts drivers of altered gene expression in nonalcoholic steatohepatitis. Biochemical Pharmacology |
| Lake AD, Wood CE, Bhat VS, et al. (2015) Dose and Effect Thresholds for Early Key Events in a PPARα-Mediated Mode of Action. Toxicological Sciences : An Official Journal of the Society of Toxicology |
| Lake AD, Novak P, Shipkova P, et al. (2015) Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease. Amino Acids. 47: 603-15 |
| Canet MJ, Hardwick RN, Lake AD, et al. (2015) Renal xenobiotic transporter expression is altered in multiple experimental models of nonalcoholic steatohepatitis. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 266-72 |
| Hardwick RN, Clarke JD, Lake AD, et al. (2014) Increased susceptibility to methotrexate-induced toxicity in nonalcoholic steatohepatitis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 142: 45-55 |
| Clarke JD, Hardwick RN, Lake AD, et al. (2014) Synergistic interaction between genetics and disease on pravastatin disposition. Journal of Hepatology. 61: 139-47 |
| Clarke JD, Hardwick RN, Lake AD, et al. (2014) Experimental nonalcoholic steatohepatitis increases exposure to simvastatin hydroxy acid by decreasing hepatic organic anion transporting polypeptide expression. The Journal of Pharmacology and Experimental Therapeutics. 348: 452-8 |