Todd Mereniuk, Ph.D.
Affiliations: | 2012 | Experimental Oncology | University of Alberta, Edmonton, Alberta, Canada |
Area:
Molecular Biology, OncologyGoogle:
"Todd Mereniuk"Parents
Sign in to add mentor| Michael Weinfeld | grad student | 2012 | University of Alberta | |
| (Synthetic Lethal Targeting of Polynucleotide Kinase/Phosphatase and its Potential Role in Directed Cancer Therapies.) | ||||
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Publications
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| Mereniuk TR, El Gendy MA, Mendes-Pereira AM, et al. (2013) Synthetic lethal targeting of PTEN-deficient cancer cells using selective disruption of polynucleotide kinase/phosphatase. Molecular Cancer Therapeutics. 12: 2135-44 |
| Mereniuk TR, Maranchuk RA, Schindler A, et al. (2012) Genetic screening for synthetic lethal partners of polynucleotide kinase/phosphatase: potential for targeting SHP-1-depleted cancers. Cancer Research. 72: 5934-44 |
| Freschauf GK, Mani RS, Mereniuk TR, et al. (2010) Mechanism of action of an imidopiperidine inhibitor of human polynucleotide kinase/phosphatase. The Journal of Biological Chemistry. 285: 2351-60 |
| Freschauf GK, Karimi-Busheri F, Ulaczyk-Lesanko A, et al. (2009) Identification of a small molecule inhibitor of the human DNA repair enzyme polynucleotide kinase/phosphatase. Cancer Research. 69: 7739-46 |