Xingsheng Shu, Ph.D.
Affiliations: | 2012 | Clinical Oncology | The Chinese University of Hong Kong, Hong Kong, Hong Kong |
Area:
Oncology, Genetics, Molecular BiologyGoogle:
"Xingsheng Shu"Parents
Sign in to add mentorQian Tao | grad student | 2012 | Chinese University of Hong Kong | |
(Identification, Epigenetic and Functional Characterization of Novel Tumor Suppressor Genes in Human Cancers.) |
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Publications
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Chen Y, Ying Y, Ma W, et al. (2024) Targeting the epigenetic reader ENL inhibits super-enhancer-driven oncogenic transcription and synergizes with BET inhibition to suppress tumor progression. Cancer Research |
Muluh TA, Shu XS, Ying Y. (2023) Targeting cancer metabolic vulnerabilities for advanced therapeutic efficacy. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 162: 114658 |
Li L, Shu XS, Geng H, et al. (2023) A novel tumor suppressor encoded by a 1p36.3 lncRNA functions as a phosphoinositide-binding protein repressing AKT phosphorylation/activation and promoting autophagy. Cell Death and Differentiation |
Chen Y, Ying Y, Wang M, et al. (2023) A distal super-enhancer activates oncogenic ETS2 via recruiting MECOM in inflammatory bowel disease and colorectal cancer. Cell Death & Disease. 14: 8 |
Ying Y, Wang M, Chen Y, et al. (2022) Zinc finger protein 280C contributes to colorectal tumorigenesis by maintaining epigenetic repression at H3K27me3-marked loci. Proceedings of the National Academy of Sciences of the United States of America. 119: e2120633119 |
Liu S, Jiang Y, Yang H, et al. (2021) BIX-01294 enhances the effect of chemotherapy on colorectal cancer by inhibiting the expression of stemness genes. Biochemical and Biophysical Research Communications. 590: 169-176 |
Zhang J, Ying Y, Li M, et al. (2020) Targeted inhibition of KDM6 histone demethylases eradicates tumor-initiating cells via enhancer reprogramming in colorectal cancer. Theranostics. 10: 10016-10030 |
Zhang Y, Cheng Y, Zhang Z, et al. (2020) CDCA2 Inhibits Apoptosis and Promotes Cell Proliferation in Prostate Cancer and Is Directly Regulated by HIF-1α Pathway. Frontiers in Oncology. 10: 725 |
Zhao Y, Zhu H, Yang Y, et al. (2020) AQP1 suppression by ATF4 triggers trabecular meshwork tissue remodelling in ET-1-induced POAG. Journal of Cellular and Molecular Medicine |
Li L, Fan Y, Huang X, et al. (2019) Tumor Suppression of Ras GTPase-Activating Protein RASA5 through Antagonizing Ras Signaling Perturbation in Carcinomas. Iscience. 21: 1-18 |