Yong Lei, Ph.D.
Affiliations: | 2013 | The Chinese University of Hong Kong, Hong Kong, Hong Kong |
Area:
Genetics, Molecular Biology, General BiologyGoogle:
"Yong Lei"Parents
Sign in to add mentor| Zhao Hui | grad student | 2013 | Chinese University of Hong Kong | |
| (Efficient Targeted Gene Disruption in Xenopus Embryos Using Engineered Transcription Activator-Like Effector Nucleases (TALENs).) | ||||
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Publications
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| Lei Y, Huang YH, Goodell MA. (2018) DNA methylation and de-methylation using hybrid site-targeting proteins. Genome Biology. 19: 187 |
| Su J, Huang YH, Cui X, et al. (2018) Homeobox oncogene activation by pan-cancer DNA hypermethylation. Genome Biology. 19: 108 |
| Jeong M, Park HJ, Celik H, et al. (2018) Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo. Cell Reports. 23: 1-10 |
| Lei Y, Goodell MA. (2018) Polycomb Group Proteins Recruit TET1 to Remove Aberrant DNA Methylation in Murine Embryonic Stem Cells Blood. 132: 2571-2571 |
| Huang YH, Su J, Lei Y, et al. (2017) DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A. Genome Biology. 18: 176 |
| Lei Y, Zhang X, Su J, et al. (2017) Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein. Nature Communications. 8: 16026 |
| Zhang X, Su J, Jeong M, et al. (2016) DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells. Nature Genetics |
| Liu Z, Cheng TT, Shi Z, et al. (2016) Efficient genome editing of genes involved in neural crest development using the CRISPR/Cas9 system in Xenopus embryos. Cell & Bioscience. 6: 22 |
| Liu Y, Luo D, Lei Y, et al. (2014) A highly effective TALEN-mediated approach for targeted gene disruption in Xenopus tropicalis and zebrafish. Methods (San Diego, Calif.). 69: 58-66 |
| Hu J, Lei Y, Wong WK, et al. (2014) Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors. Nucleic Acids Research. 42: 4375-90 |