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Yukun Zhang, Ph.D.

Affiliations: 
2013 Food Science and Human Nutrition University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Nutrition, Pathology, Molecular Biology
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"Yukun Zhang"
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William G. Helferich grad student 2013 UIUC
 (Epigenetic modifications on wnt genes by dietary genistein during colon cancer development.)

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Publications

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Zhang Y, Wang H, Zhou D, et al. (2015) High-fat diet caused widespread epigenomic differences on hepatic methylome in rat. Physiological Genomics. 47: 514-23
Cai K, Yen J, Yin Q, et al. (2015) Redox-Responsive Self-Assembled Chain-Shattering Polymeric Therapeutics. Biomaterials Science. 3: 1061-1065
Liu Y, Hilakivi-Clarke L, Zhang Y, et al. (2015) Isoflavones in soy flour diet have different effects on whole-genome expression patterns than purified isoflavone mix in human MCF-7 breast tumors in ovariectomized athymic nude mice. Molecular Nutrition & Food Research
Yang X, Belosay A, Hartman JA, et al. (2015) Dietary soy isoflavones increase metastasis to lungs in an experimental model of breast cancer with bone micro-tumors. Clinical & Experimental Metastasis. 32: 323-33
Zhang Y, Wang W, Yang X, et al. (2015) Abstract 899: High fat diet induced DNA methylation at transcription factor binding region and repressed gene expression of a metastasis suppressor E-cadherin in primary site of murine metastatic breast cancer (MBC), and promoted invasion of MBC cells to lung and liver Cancer Research. 75: 899-899
Zhang Y, Li Q, Chen H. (2013) DNA methylation and histone modifications of Wnt genes by genistein during colon cancer development. Carcinogenesis. 34: 1756-63
Zhang Y, Li Q, Zhou D, et al. (2013) Genistein, a soya isoflavone, prevents azoxymethane-induced up-regulation of WNT/β-catenin signalling and reduces colon pre-neoplasia in rats. The British Journal of Nutrition. 109: 33-42
Zheng S, Li Q, Zhang Y, et al. (2012) Histone deacetylase 3 (HDAC3) participates in the transcriptional repression of the p16 (INK4a) gene in mammary gland of the female rat offspring exposed to an early-life high-fat diet. Epigenetics. 7: 183-90
Zhang X, Zhou D, Strakovsky R, et al. (2012) Hepatic cellular senescence pathway genes are induced through histone modifications in a diet-induced obese rat model. American Journal of Physiology. Gastrointestinal and Liver Physiology. 302: G558-64
Zhang Y, Chen H. (2011) Genistein, an epigenome modifier during cancer prevention. Epigenetics. 6: 888-91
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