Richard M. Reznick, Ph.D.
Affiliations: | 2011 | Yale University, New Haven, CT |
Area:
Molecular Biology, Genetics, AgingGoogle:
"Richard Reznick"Parents
Sign in to add mentor| Gerald Shalman | grad student | 2011 | Yale | |
| (Age-Associated Defects in AMP-Activated Protein Kinase Activity and Mitochondrial Biogenesis.) | ||||
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Publications
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| Choi CS, Befroy DE, Codella R, et al. (2008) Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism. Proceedings of the National Academy of Sciences of the United States of America. 105: 19926-31 |
| Morino K, Neschen S, Bilz S, et al. (2008) Muscle-specific IRS-1 Ser->Ala transgenic mice are protected from fat-induced insulin resistance in skeletal muscle. Diabetes. 57: 2644-51 |
| Choi CS, Savage DB, Abu-Elheiga L, et al. (2007) Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 104: 16480-5 |
| Choi CS, Fillmore JJ, Kim JK, et al. (2007) Overexpression of uncoupling protein 3 in skeletal muscle protects against fat-induced insulin resistance. The Journal of Clinical Investigation. 117: 1995-2003 |
| Reznick RM, Zong H, Li J, et al. (2007) Aging-associated reductions in AMP-activated protein kinase activity and mitochondrial biogenesis. Cell Metabolism. 5: 151-6 |
| Reznick RM, Shulman GI. (2006) The role of AMP-activated protein kinase in mitochondrial biogenesis. The Journal of Physiology. 574: 33-9 |
| Lin J, Wu PH, Tarr PT, et al. (2004) Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice. Cell. 119: 121-35 |