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Robyn L. Maher, Ph.D.

Affiliations: 
2006 University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Biochemistry
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"Robyn Maher"
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Linda Bloom grad student 2006 UF Gainesville
 (Kinetic characterization and coordination of human alkyladenine DNA glycosylase and human apurinic /apyrimidinic endonuclease 1.)

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Publications

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Marsden CG, Jaruga P, Coskun E, et al. (2020) Expression of a germline variant in the N-terminal domain of the human DNA glycosylase NTHL1 induces cellular transformation without impairing enzymatic function or substrate specificity. Oncotarget. 11: 2262-2272
Maher RL, Wallace SS, Pederson DS. (2019) The lyase activity of bifunctional DNA glycosylases and the 3'-diesterase activity of APE1 contribute to the repair of oxidized bases in nucleosomes. Nucleic Acids Research
Maher RL, Marsden CG, Averill AM, et al. (2017) Human cells contain a factor that facilitates the DNA glycosylase-mediated excision of oxidized bases from occluded sites in nucleosomes. Dna Repair. 57: 91-97
Maher RL, Prasad A, Rizvanova O, et al. (2013) Contribution of DNA unwrapping from histone octamers to the repair of oxidatively damaged DNA in nucleosomes. Dna Repair. 12: 964-71
Maher RL, Morrical SW. (2013) Coordinated Binding of Single-Stranded and Double-Stranded DNA by UvsX Recombinase. Plos One. 8: e66654
Branagan AM, Maher RL, Morrical SW. (2012) Assembly and dynamics of Gp59-Gp32-single-stranded DNA (ssDNA), a DNA helicase loading complex required for recombination-dependent replication in bacteriophage T4. The Journal of Biological Chemistry. 287: 19070-81
Maher RL, Branagan AM, Morrical SW. (2011) Coordination of DNA replication and recombination activities in the maintenance of genome stability. Journal of Cellular Biochemistry. 112: 2672-82
Maher RL, Bloom LB. (2007) Pre-steady-state kinetic characterization of the AP endonuclease activity of human AP endonuclease 1. The Journal of Biological Chemistry. 282: 30577-85
Maher RL, Vallur AC, Feller JA, et al. (2007) Slow base excision by human alkyladenine DNA glycosylase limits the rate of formation of AP sites and AP endonuclease 1 does not stimulate base excision. Dna Repair. 6: 71-81
Vallur AC, Maher RL, Bloom LB. (2005) The efficiency of hypoxanthine excision by alkyladenine DNA glycosylase is altered by changes in nearest neighbor bases. Dna Repair. 4: 1088-98
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