Parents
Sign in to add mentorRene Medema | grad student | 2006-2012 | Netherlands Cancer Institute |
Gary Karpen | post-doc | 2013-2018 | UC Berkeley (Neurotree) |
Children
Sign in to add traineeMarit A. E. van Bueren | grad student | 2020-2024 | Utrecht |
Aditya A Dixit | grad student | 2022-2026 |
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Publications
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Wensveen MR, Dixit AA, van Schendel R, et al. (2024) Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair. Nature Communications. 15: 8984 |
Kendek A, Sandron A, Lambooij JP, et al. (2024) DNA double-strand break movement in heterochromatin depends on the histone acetyltransferase dGcn5. Nucleic Acids Research |
Hoevenaar WHM, Janssen A, Quirindongo AI, et al. (2020) Degree and site of chromosomal instability define its oncogenic potential. Nature Communications. 11: 1501 |
Janssen A, Colmenares SU, Lee T, et al. (2018) Timely double-strand break repair and pathway choice in pericentromeric heterochromatin depend on the histone demethylase dKDM4A. Genes & Development |
Janssen A, Colmenares SU, Karpen GH. (2018) Heterochromatin: Guardian of the Genome. Annual Review of Cell and Developmental Biology |
Janssen A, Breuer GA, Brinkman EK, et al. (2016) A single double-strand break system reveals repair dynamics and mechanisms in heterochromatin and euchromatin. Genes & Development. 30: 1645-57 |
Koch A, Maia A, Janssen A, et al. (2015) Molecular basis underlying resistance to Mps1/TTK inhibitors. Oncogene |
Maia AR, de Man J, Boon U, et al. (2015) Inhibition of the spindle assembly checkpoint kinase TTK enhances the efficacy of docetaxel in a triple-negative breast cancer model. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 26: 2180-92 |
Medema R, Maia AR, Janssen A, et al. (2014) 6INTHE INTERFACE BETWEEN CANCER NUMERICAL AND STRUCTURAL CHROMOSOMAL INSTABILITY: MECHANISMS ACCELERATING CANCER DIVERSITY. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 25: iv4 |
Janssen A, Beerling E, Medema R, et al. (2013) Intravital FRET imaging of tumor cell viability and mitosis during chemotherapy. Plos One. 8: e64029 |