Douglas Gould

Affiliations: 
University of California, San Francisco, San Francisco, CA 
Area:
extracellular matrix
Website:
http://vision.ucsf.edu/gould/Gouldlab/
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"Douglas Gould"

Parents

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Michael Walter grad student 2001 University of Alberta
 (Analysis of the genetic basis of Axenfeld Rieger malformations.)
Simon WM John post-doc 2006 The Jackson Laboratory (Chemistry Tree)

Children

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Xiaowei Wang post-doc (Neurotree)
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Publications

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Mao M, Ishikawa Y, Labelle-Dumais C, et al. (2025) A multifunction murine Col4a1 allele reveals potential gene therapy parameters for Gould syndrome. The Journal of Cell Biology. 224
Labelle-Dumais C, Mazur C, Kaya S, et al. (2024) Skeletal pathology in mouse models of Gould syndrome is partially alleviated by genetically reducing TGFβ signaling. Matrix Biology : Journal of the International Society For Matrix Biology
Cozzitorto C, Peltz Z, Flores LM, et al. (2024) Evaluating neural crest cell migration in a Col4a1 mutant mouse model of ocular anterior segment dysgenesis. Cells & Development. 203926
Mao M, Kuo YM, Yu AK, et al. (2024) TGFβ Signaling Dysregulation May Contribute to COL4A1-Related Glaucomatous Optic Nerve Damage. Investigative Ophthalmology & Visual Science. 65: 15
Yamasaki E, Ali S, Sanchez Solano A, et al. (2023) Faulty TRPM4 channels underlie age-dependent cerebral vascular dysfunction in Gould syndrome. Proceedings of the National Academy of Sciences of the United States of America. 120: e2217327120
Branyan K, Labelle-Dumais C, Wang X, et al. (2022) Elevated TGFβ Signaling Contributes to Cerebral Small Vessel Disease in Mouse Models of Gould Syndrome. Matrix Biology : Journal of the International Society For Matrix Biology
Mao M, Labelle-Dumais C, Tufa SF, et al. (2022) Elevated TGFβ signaling contributes to ocular anterior segment dysgenesis in Col4a1 mutant mice. Matrix Biology : Journal of the International Society For Matrix Biology
Mao M, Popli T, Jeanne M, et al. (2021) Identification of fibronectin 1 as a candidate genetic modifier in a Col4a1 mutant mouse model of Gould syndrome. Disease Models & Mechanisms. 14
Mao M, Popli T, Jeanne M, et al. (2021) Identification of fibronectin 1 as a candidate genetic modifier in a mutant mouse model of Gould syndrome. Disease Models & Mechanisms
Ishikawa Y, Mizuno N, Holden P, et al. (2020) The novel missense mutation Met48Lys in FKBP22 changes its structure and functions. Scientific Reports. 10: 497
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