Nicolas Skrypek

Affiliations: 
Lille 2 
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"Nicolas Skrypek"

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Isabelle van Seuningen grad student 2012 Lille 2
 (Rôles de la mucine membranaire MUC4 et de son partenaire ErbB2 sur les propriétés biologiques des cellules humaines d'adénocarcinomes pancréatiques : implication dans la chimio-résistance à la gemcitabine et aux drogues du protocole FOLFIRINOX)
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Publications

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So JY, Yang HH, Park WY, et al. (2022) DNA methyltransferase 3B-mediated intra-tumoral heterogeneity and therapeutic targeting in breast cancer recurrence and metastasis. Molecular Cancer Research : McR
Stoup N, Liberelle M, Schulz C, et al. (2021) The EGF Domains of MUC4 Oncomucin Mediate HER2 Binding Affinity and Promote Pancreatic Cancer Cell Tumorigenesis. Cancers. 13
Vandamme N, Denecker G, Bruneel K, et al. (2020) The EMT transcription factor ZEB2 promotes proliferation of primary and metastatic melanoma while suppressing an invasive, mesenchymal-like phenotype. Cancer Research
Yang L, So JY, Skrypek N, et al. (2020) Induction of DNMT3B by PGE2 and IL6 at distant metastatic sites promotes epigenetic modification and breast cancer colonization. Cancer Research
Skrypek N, Bruneel K, Vandewalle C, et al. (2018) ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition. Epigenetics & Chromatin. 11: 70
Drubay V, Skrypek N, Cordiez L, et al. (2018) TGF-βRII Knock-down in Pancreatic Cancer Cells Promotes Tumor Growth and Gemcitabine Resistance. Importance of STAT3 Phosphorylation on S727. Cancers. 10
Skrypek N, Goossens S, De Smedt E, et al. (2017) Epithelial-to-Mesenchymal Transition: Epigenetic Reprogramming Driving Cellular Plasticity. Trends in Genetics : Tig
Bourcy M, Skrypek N, Thompson EW, et al. (2017) Abstract LB-147: EMT transcription factors induce tissue factor expression and pro-coagulant properties, supporting early metastasis of circulating tumor cells Cancer Research. 77
So JY, Skrypek N, Wang X, et al. (2017) Abstract 2843: DNMT3B mediated DNA methylation and epigenetic reprogramming of metastatic cancer cells Cancer Research. 77: 2843-2843
Bourcy M, Suarez-Carmona M, Lambert J, et al. (2016) Tissue factor induced by epithelial-mesenchymal transition triggers a pro-coagulant state that drives metastasis of circulating tumor cells. Cancer Research
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