Andrew R. Marks, MD

Affiliations: 
Physiology Columbia University College of Physicians and Surgeons, New York, NY, United States 
Area:
Ion channels, Ryanodine receptor biology, rapamycin resistance
Website:
http://www.markslab.columbia.edu
Google:
"Andrew R Marks Chair"
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Publications

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Weninger G, Miotto MC, Tchagou C, et al. (2024) Structural insights into the regulation of RyR1 by S100A1. Proceedings of the National Academy of Sciences of the United States of America. 121: e2400497121
Todd JJ, Lawal TA, Chrismer IC, et al. (2024) Rycal S48168 (ARM210) for -related myopathies: a phase one, open-label, dose-escalation trial. Eclinicalmedicine. 68: 102433
Souidi M, Resta J, Dridi H, et al. (2024) Ryanodine receptor dysfunction causes senescence and fibrosis in Duchenne dilated cardiomyopathy. Journal of Cachexia, Sarcopenia and Muscle
Dridi H, Santulli G, Bahlouli L, et al. (2023) Mitochondrial Calcium Overload Plays a Causal Role in Oxidative Stress in the Failing Heart. Biomolecules. 13
Dridi H, Liu Y, Reiken S, et al. (2023) Heart failure-induced cognitive dysfunction is mediated by intracellular Ca leak through ryanodine receptor type 2. Nature Neuroscience
Martuscello RT, Chen ML, Reiken S, et al. (2023) Defective cerebellar ryanodine receptor type 1 and endoplasmic reticulum calcium 'leak' in tremor pathophysiology. Acta Neuropathologica
Marks AR. (2023) Targeting ryanodine receptors to treat human diseases. The Journal of Clinical Investigation. 133
Miotto MC, Weninger G, Dridi H, et al. (2022) Structural analyses of human ryanodine receptor type 2 channels reveal the mechanisms for sudden cardiac death and treatment. Science Advances. 8: eabo1272
Melville Z, Dridi H, Yuan Q, et al. (2022) A drug and ATP binding site in type 1 ryanodine receptor. Structure (London, England : 1993)
Dridi H, Forrester F, Umanskaya A, et al. (2022) Role of oxidation of excitation-contraction coupling machinery in age-dependent loss of muscle function in . Elife. 11
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