Daniel W. Summers, Ph.D.

Affiliations: 
Neurobiology Washington University, Saint Louis, St. Louis, MO 
Area:
Neurodevelopment
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"Daniel Summers"

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Douglas Cyr grad student 2011 UNC Chapel Hill
 (Cytoprotective strategies that selectively recognize and suppress protein aggregation in the cell.)
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Publications

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Vermulst M, Denney AS, Lang MJ, et al. (2015) Corrigendum: Transcription errors induce proteotoxic stress and shorten cellular lifespan. Nature Communications. 6: 8738
Vermulst M, Denney AS, Lang MJ, et al. (2015) Transcription errors induce proteotoxic stress and shorten cellular lifespan. Nature Communications. 6: 8065
Summers DW, Wolfe KJ, Ren HY, et al. (2013) The Type II Hsp40 Sis1 cooperates with Hsp70 and the E3 ligase Ubr1 to promote degradation of terminally misfolded cytosolic protein. Plos One. 8: e52099
Summers DW, Cyr DM. (2011) Use of yeast as a system to study amyloid toxicity. Methods (San Diego, Calif.). 53: 226-31
Summers DW, Wolfe KJ, Cyr DM. (2011) Chaperone-Dependent Amyloid Assembly and Prion Toxicity Protein Chaperones and Protection From Neurodegenerative Diseases. 261-276
Douglas PM, Summers DW, Ren HY, et al. (2009) Reciprocal efficiency of RNQ1 and polyglutamine detoxification in the cytosol and nucleus. Molecular Biology of the Cell. 20: 4162-73
Kota P, Summers DW, Ren HY, et al. (2009) Identification of a consensus motif in substrates bound by a Type I Hsp40. Proceedings of the National Academy of Sciences of the United States of America. 106: 11073-8
Summers DW, Douglas PM, Cyr DM. (2009) Prion propagation by Hsp40 molecular chaperones. Prion. 3: 59-64
Douglas PM, Summers DW, Cyr DM. (2009) Molecular chaperones antagonize proteotoxicity by differentially modulating protein aggregation pathways. Prion. 3: 51-8
Summers DW, Douglas PM, Ramos CH, et al. (2009) Polypeptide transfer from Hsp40 to Hsp70 molecular chaperones. Trends in Biochemical Sciences. 34: 230-3
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