mark szczelkun
Affiliations: | Biochemistry | University of Bristol, Bristol, England, United Kingdom |
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"mark szczelkun"
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| Göse M, Magill EE, Hughes-Games A, et al. (2024) Short-range translocation by a restriction enzyme motor triggers diffusion along DNA. Nature Chemical Biology |
| Naqvi MM, Lee L, Montaguth OET, et al. (2022) CRISPR-Cas12a-mediated DNA clamping triggers target-strand cleavage. Nature Chemical Biology |
| Torres Montaguth OE, Cross SJ, Ingram KWA, et al. (2021) ENDO-Pore: high-throughput linked-end mapping of single DNA cleavage events using nanopore sequencing. Nucleic Acids Research |
| Mullally G, van Aelst K, Naqvi MM, et al. (2020) 5' modifications to CRISPR-Cas9 gRNA can change the dynamics and size of R-loops and inhibit DNA cleavage. Nucleic Acids Research. 48: 6811-6823 |
| van Aelst K, Martínez-Santiago CJ, Cross SJ, et al. (2019) The Effect of DNA Topology on Observed Rates of R-Loop Formation and DNA Strand Cleavage by CRISPR Cas12a. Genes. 10 |
| Nirwan N, Singh P, Mishra GG, et al. (2018) Hexameric assembly of the AAA+ protein McrB is necessary for GTPase activity. Nucleic Acids Research |
| Toliusis P, Zaremba M, Silanskas A, et al. (2017) CgII cleaves DNA using a mechanism distinct from other ATP-dependent restriction endonucleases. Nucleic Acids Research. 45: 8435-8447 |
| Kulkarni M, Nirwan N, van Aelst K, et al. (2016) Structural insights into DNA sequence recognition by Type ISP restriction-modification enzymes. Nucleic Acids Research. 44: 4396-408 |
| Tóth J, Bollins J, Szczelkun MD. (2015) Re-evaluating the kinetics of ATP hydrolysis during initiation of DNA sliding by Type III restriction enzymes. Nucleic Acids Research. 43: 10870-81 |
| van Aelst K, Saikrishnan K, Szczelkun MD. (2015) Mapping DNA cleavage by the Type ISP restriction-modification enzymes following long-range communication between DNA sites in different orientations. Nucleic Acids Research. 43: 10430-43 |