Kirti Sharma

Affiliations: 
Max Planck Institute of Biochemistry Martinsried / Munich 
Area:
Proteomics, Drug Discovery, Cell Signaling, Chemical Biology
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"Kirti Sharma"

Collaborators

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F. Ulrich Hartl collaborator (Neurotree)
Jeffrey J Liu collaborator (Chemistry Tree)
Eric J. Rubin collaborator (Microtree)
Mikael Simons collaborator (Neurotree)
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Publications

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Csibi A, Yang B, Chutake Y, et al. (2020) Abstract LB-088: A STAT3 selective targeted protein degrader decreases the immunesuppressive tumor microenvironment and drives antitumor activity in preclinical models Cancer Research. 80
Kelleher JF, Campbell V, Chen J, et al. (2019) Abstract LB-272: KYM-001, a first-in-class oral IRAK4 protein degrader, induces tumor regression in xenograft models of MYD88-mutant ABC DLBCL alone and in combination with BTK inhibition Cancer Research. 79
Liu JJ, Sharma K, Zangrandi L, et al. (2018) In vivo brain GPCR signaling elucidated by phosphoproteomics. Science (New York, N.Y.). 360
Marakalala MJ, Raju RM, Sharma K, et al. (2016) Inflammatory signaling in human tuberculosis granulomas is spatially organized. Nature Medicine
Sharma K, Schmitt S, Bergner CG, et al. (2015) Cell type- and brain region-resolved mouse brain proteome. Nature Neuroscience
Zeigerer A, Bogorad RL, Sharma K, et al. (2015) Regulation of liver metabolism by the endosomal GTPase Rab5. Cell Reports. 11: 884-92
Sharma K, D'Souza RC, Tyanova S, et al. (2014) Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling. Cell Reports. 8: 1583-94
D'Souza RC, Knittle AM, Nagaraj N, et al. (2014) Time-resolved dissection of early phosphoproteome and ensuing proteome changes in response to TGF-β. Science Signaling. 7: rs5
Gupta M, Sajid A, Sharma K, et al. (2014) HupB, a nucleoid-associated protein of Mycobacterium tuberculosis, is modified by serine/threonine protein kinases in vivo. Journal of Bacteriology. 196: 2646-57
Sharma K, Vabulas RM, Macek B, et al. (2012) Quantitative proteomics reveals that Hsp90 inhibition preferentially targets kinases and the DNA damage response. Molecular & Cellular Proteomics : McP. 11: M111.014654
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