Joseph A. Beavo

Affiliations: 
Pharmacology University of Washington, Seattle, Seattle, WA 
Area:
control of signal transduction by cyclic nucleotide second messengers in the cell
Website:
http://depts.washington.edu/pde/beavolab/personnel.html#Joe
Google:
"Joseph A. Beavo"
Bio:

http://www.nasonline.org/member-directory/members/3001664.html
http://depts.washington.edu/pde/beavolab/beavopubs.html

Cross-listing: Chemistry Tree

Parents

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Joel G. Hardman grad student 1970 Vanderbilt (Neurotree)
Earl W. Sutherland grad student 1970 Vanderbilt (Neurotree)
 (Cyclic nucleotide phosphodiesterase activity in rat and beef tissues)
Edwin G. Krebs post-doc UC Davis (Neurotree)

Children

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Peter G. Barr-Gillespie grad student University of Washington
Terry A. Cook grad student 2001 University of Washington (Chemistry Tree)
Albert Y. Wu grad student 2003 University of Washington (Chemistry Tree)
Daming Huang grad student 2004 University of Washington (Chemistry Tree)
Sunil Laxman grad student 2006 University of Washington (Chemistry Tree)
James Surapisitchat grad student 2007 University of Washington (Chemistry Tree)
Candace M. Adamo grad student 2011 University of Washington (Chemistry Tree)
Angie L. Hertz grad student 2011 University of Washington (Chemistry Tree)
Li-Chun L. Tsai grad student 2011 University of Washington (Chemistry Tree)
Stephen M. Kraynik grad student 2013 University of Washington (Chemistry Tree)
Harry Charbonneau post-doc 1984-1987 University of Washington (Chemistry Tree)
BETA: Related publications

Publications

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Golkowski M, Vidadala VN, Lau HT, et al. (2020) Kinobead/LC-MS Phosphokinome Profiling Enables Rapid Analyses of Kinase-Dependent Cell Signaling Networks. Journal of Proteome Research
Beltejar MG, Lau HT, Golkowski MG, et al. (2017) Analyses of PDE-regulated phosphoproteomes reveal unique and specific cAMP-signaling modules in T cells. Proceedings of the National Academy of Sciences of the United States of America
Shimizu-Albergine M, Van Yserloo B, Golkowski MG, et al. (2016) SCAP/SREBP pathway is required for the full steroidogenic response to cyclic AMP. Proceedings of the National Academy of Sciences of the United States of America
Egbert JR, Uliasz TF, Shuhaibar LC, et al. (2016) Luteinizing Hormone Causes Phosphorylation and Activation of the cGMP Phosphodiesterase PDE5 in Rat Ovarian Follicles, Contributing, Together with PDE1 Activity, to the Resumption of Meiosis. Biology of Reproduction
Golkowski M, Shimizu-Albergine M, Suh HW, et al. (2015) Studying mechanisms of cAMP and cyclic nucleotide phosphodiesterase signaling in Leydig cell function with phosphoproteomics. Cellular Signalling
Patrucco E, Domes K, Sbroggió M, et al. (2014) Roles of cGMP-dependent protein kinase I (cGKI) and PDE5 in the regulation of Ang II-induced cardiac hypertrophy and fibrosis. Proceedings of the National Academy of Sciences of the United States of America. 111: 12925-9
Lukowski R, Krieg T, Rybalkin SD, et al. (2014) Turning on cGMP-dependent pathways to treat cardiac dysfunctions: boom, bust, and beyond. Trends in Pharmacological Sciences. 35: 404-13
Demirbas D, Wyman AR, Shimizu-Albergine M, et al. (2013) A yeast-based chemical screen identifies a PDE inhibitor that elevates steroidogenesis in mouse Leydig cells via PDE8 and PDE4 inhibition. Plos One. 8: e71279
Rybalkin SD, Hinds TR, Beavo JA. (2013) Enzyme assays for cGMP hydrolyzing phosphodiesterases. Methods in Molecular Biology (Clifton, N.J.). 1020: 51-62
Brown KM, Day JP, Huston E, et al. (2013) Phosphodiesterase-8A binds to and regulates Raf-1 kinase. Proceedings of the National Academy of Sciences of the United States of America. 110: E1533-42
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