Sergey V. Karakashev

Affiliations: 
2011-2015 Biochemistry Drexel University College of Medicine, Philadelphia, PA, United States 
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"Sergey Karakashev"

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Mauricio J. Reginato grad student 2011-2015 Drexel Medical School
 (Role of hypoxia in mediating resistance to breast cancer therapy)
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Publications

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Kumari S, Gupta S, Jamil A, et al. (2024) Exploring Metabolic Approaches for Epithelial Ovarian Cancer Therapy. Journal of Cellular Physiology. e31495
Liu H, Lin J, Zhou W, et al. (2022) KDM5A Inhibits Antitumor Immune Responses Through Downregulation of the Antigen-Presentation Pathway in Ovarian Cancer. Cancer Immunology Research. OF1-OF11
Lin J, Liu H, Fukumoto T, et al. (2021) Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer. Nature Communications. 12: 5321
Wu S, Fukumoto T, Lin J, et al. (2021) Targeting glutamine dependence through GLS1 inhibition suppresses ARID1A-inactivated clear cell ovarian carcinoma. Nature Cancer. 2: 189-200
Karakashev S, Zhang R. (2020) Targeting CARM1 in ovarian cancer with EZH2 and PARP inhibitors. Molecular & Cellular Oncology. 7: 1760675
Fukumoto T, Fatkhutdinov N, Zundell JA, et al. (2019) HDAC6 inhibition synergizes with anti-PD-L1 therapy in ARID1A-inactivated ovarian cancer. Cancer Research
Fukumoto T, Zhu H, Nacarelli T, et al. (2019) N6-methylation of adenosine (m6A) of FZD10 mRNA contributes to PARP inhibitor resistance. Cancer Research
Fukumoto T, Park PH, Wu S, et al. (2018) Repurposing Pan-HDAC Inhibitors for ARID1A-Mutated Ovarian Cancer. Cell Reports. 22: 3393-3400
Karakashev S, Zhu H, Wu S, et al. (2018) CARM1-expressing ovarian cancer depends on the histone methyltransferase EZH2 activity. Nature Communications. 9: 631
Karakashev S, Zhu H, Yokoyama Y, et al. (2017) BET Bromodomain Inhibition Synergizes with PARP Inhibitor in Epithelial Ovarian Cancer. Cell Reports. 21: 3398-3405
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