Ruben Boon

Affiliations: 
MGH cancer center 
Area:
Metabolism, epigenetics
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"Ruben Boon"

Parents

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Catherine M. Verfaillie grad student 2013-2018 (BME Tree)
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Publications

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Chui JS, Izuel-Idoype T, Qualizza A, et al. (2023) Osmolar Modulation Drives Reversible Cell Cycle Exit and Human Pluripotent Cell Differentiation via NF-κВ and WNT Signaling. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2307554
Linder SJ, Bernasocchi T, Martínez-Pastor B, et al. (2023) Inhibition of the proline metabolism rate-limiting enzyme P5CS allows proliferation of glutamine-restricted cancer cells. Nature Metabolism
Vanmarcke G, Sai-Hong Chui J, Cooreman A, et al. (2023) Automated generation of hiPSC-derived hepatic progeny by cost-efficient compounds. Stem Cells (Dayton, Ohio)
Tricot T, Thibaut HJ, Abbasi K, et al. (2022) Metabolically Improved Stem Cell Derived Hepatocyte-Like Cells Support HBV Life Cycle and Are a Promising Tool for HBV Studies and Antiviral Drug Screenings. Biomedicines. 10
Moreno-Torres M, Kumar M, García-Llorens G, et al. (2022) A Novel UPLC-MS Metabolomic Analysis-Based Strategy to Monitor the Course and Extent of iPSC Differentiation to Hepatocytes. Journal of Proteome Research
Kumar M, Toprakhisar B, Van Haele M, et al. (2021) A fully defined matrix to support a pluripotent stem cell derived multi-cell-liver steatohepatitis and fibrosis model. Biomaterials. 276: 121006
Fazal R, Boeynaems S, Swijsen A, et al. (2021) HDAC6 inhibition restores TDP-43 pathology and axonal transport defects in human motor neurons with TARDBP mutations. The Embo Journal. e106177
Ter Braak B, Niemeijer M, Boon R, et al. (2021) Systematic transcriptome-based comparison of cellular adaptive stress response activation networks in hepatic stem cell-derived progeny and primary human hepatocytes. Toxicology in Vitro : An International Journal Published in Association With Bibra. 73: 105107
De Smedt J, van Os EA, Talon I, et al. (2021) PU.1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells. Cell Death & Disease. 12: 84
Boon R, Kumar M, Tricot T, et al. (2020) Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines. Nature Communications. 11: 1393
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