Changkyu Gu, Ph.D.

Affiliations: 
Massachusetts General Hospital, Boston, MA 
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"Changkyu Gu"
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Publications

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Zhu K, Mukherjee K, Wei C, et al. (2023) The D2D3 form of uPAR acts as an immunotoxin and may cause diabetes and kidney disease. Science Translational Medicine. 15: eabq6492
Mukherjee K, Gu C, Collins A, et al. (2022) Simultaneous stabilization of actin cytoskeleton in multiple nephron-specific cells protects the kidney from diverse injury. Nature Communications. 13: 2422
Lee H, Noh H, Mun J, et al. (2016) Anks1a regulates COPII-mediated anterograde transport of receptor tyrosine kinases critical for tumorigenesis. Nature Communications. 7: 12799
Gu C, Lee HW, Garborcauskas G, et al. (2016) Dynamin Autonomously Regulates Podocyte Focal Adhesion Maturation. Journal of the American Society of Nephrology : Jasn
Schiffer M, Teng B, Gu C, et al. (2015) Pharmacological targeting of actin-dependent dynamin oligomerization ameliorates chronic kidney disease in diverse animal models. Nature Medicine. 21: 601-9
Gu C, Chang J, Shchedrina VA, et al. (2014) Regulation of dynamin oligomerization in cells: the role of dynamin-actin interactions and its GTPase activity. Traffic (Copenhagen, Denmark). 15: 819-38
Kistler AD, Singh G, Altintas MM, et al. (2013) Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease. The Journal of Biological Chemistry. 288: 36598-609
Sever S, Chang J, Gu C. (2013) Dynamin rings: not just for fission. Traffic (Copenhagen, Denmark). 14: 1194-9
Yaddanapudi S, Altintas MM, Kistler AD, et al. (2012) CD2AP in mouse and human podocytes controls a proteolytic program that regulates cytoskeletal structure and cellular survival (The Journal of Clinical Investigation (2011) 121, 10, (3965-3980) DOI: 10.1172/JCI58552) Journal of Clinical Investigation. 122: 780
Rayego-Mateos S, Rodrigues-Díez R, Rodrigues-Díez RR, et al. (2012) Mechanisms and targets of glomerular damage Nephrology Dialysis Transplantation. 27
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