Leandro Z Agudelo

Affiliations: 
2017 Physiology and Pharmacology Karolinska Institute, Stockholm, Sweden 
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"Leandro Agudelo"
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Yang J, Vamvini M, Nigro P, et al. (2022) Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cells. Cell Metabolism. 34: 1578-1593.e6
Ferreira DMS, Cheng AJ, Agudelo LZ, et al. (2019) LIM and cysteine-rich domains 1 (LMCD1) regulates skeletal muscle hypertrophy, calcium handling, and force. Skeletal Muscle. 9: 26
Agudelo LZ, Ferreira DMS, Dadvar S, et al. (2019) Skeletal muscle PGC-1α1 reroutes kynurenine metabolism to increase energy efficiency and fatigue-resistance. Nature Communications. 10: 2767
Agudelo LZ, Ferreira DMS, Cervenka I, et al. (2018) Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation. Cell Metabolism. 27: 378-392.e5
Mills R, Taylor-Weiner H, Correia JC, et al. (2017) Neurturin is a PGC-1α1-controlled myokine that promotes motor neuron recruitment and neuromuscular junction formation. Molecular Metabolism
Cervenka I, Agudelo LZ, Ruas JL. (2017) Kynurenines: Tryptophan's metabolites in exercise, inflammation, and mental health. Science (New York, N.Y.). 357
Martinez-Redondo V, Jannig PR, Correia JC, et al. (2016) Peroxisome proliferator-activated receptor gamma coactivator-1alpha isoforms selectively regulate multiple splicing events on target genes. The Journal of Biological Chemistry
Schlittler M, Goiny M, Agudelo LZ, et al. (2016) Endurance exercise increases skeletal muscle kynurenine aminotransferases and plasma kynurenic acid in humans. American Journal of Physiology. Cell Physiology. 310: C836-40
Correia JC, Massart J, de Boer JF, et al. (2015) Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism. Molecular Metabolism. 4: 891-902
Agudelo LZ, Femenía T, Orhan F, et al. (2014) Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression. Cell. 159: 33-45
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