Yongwon Choi - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Immunology, Cell Biology

186 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Takegahara N, Kim H, Choi Y. Unraveling the intricacies of osteoclast differentiation and maturation: insight into novel therapeutic strategies for bone-destructive diseases. Experimental & Molecular Medicine. PMID 38297158 DOI: 10.1038/s12276-024-01157-7  0.312
2023 Kim H, Takegahara N, Choi Y. PP2A-Mediated GSK3β Dephosphorylation Is Required for Protocadherin-7-Dependent Regulation of Small GTPase RhoA in Osteoclasts. Cells. 12. PMID 37566044 DOI: 10.3390/cells12151967  0.305
2023 Kim H, Takegahara N, Choi Y. IgSF11-mediated phosphorylation of pyruvate kinase M2 regulates osteoclast differentiation and prevents pathological bone loss. Bone Research. 11: 17. PMID 36928396 DOI: 10.1038/s41413-023-00251-2  0.337
2023 Zhong L, Lu J, Fang J, Yao L, Yu W, Gui T, Duffy M, Holdreith N, Bautista C, Huang X, Bandyopadhyay S, Tan K, Chen C, Choi Y, Jiang JX, et al. Csf1 from marrow adipogenic precursors is required for osteoclast formation and hematopoiesis in bone. Elife. 12. PMID 36779854 DOI: 10.7554/eLife.82112  0.306
2022 Takegahara N, Kim H, Choi Y. RANKL biology. Bone. 116353. PMID 35181574 DOI: 10.1016/j.bone.2022.116353  0.323
2021 Kim H, Lee K, Kim JM, Kim MY, Kim JR, Lee HW, Chung YW, Shin HI, Kim T, Park ES, Rho J, Lee SH, Kim N, Lee SY, Choi Y, et al. Selenoprotein W ensures physiological bone remodeling by preventing hyperactivity of osteoclasts. Nature Communications. 12: 2258. PMID 33859201 DOI: 10.1038/s41467-021-22565-7  0.395
2021 Walsh MC, Choi Y. Regulation of T cell-associated tissues and T cell activation by RANKL-RANK-OPG. Journal of Bone and Mineral Metabolism. PMID 33438173 DOI: 10.1007/s00774-020-01178-y  0.365
2020 Kim H, Takegahara N, Walsh MC, Ueda J, Fujihara Y, Ikawa M, Choi Y. Protocadherin-7 contributes to maintenance of bone homeostasis through regulation of osteoclast multinucleation. Bmb Reports. PMID 32635982  0.322
2020 Jeong YH, Walsh MC, Yu J, Shen H, Wherry EJ, Choi Y. Mice Lacking the Purinergic Receptor P2X5 Exhibit Defective Inflammasome Activation and Early Susceptibility to . Journal of Immunology (Baltimore, Md. : 1950). PMID 32540996 DOI: 10.4049/Jimmunol.1901423  0.42
2020 Kim H, Takegahara N, Walsh MC, Choi Y. CD44 Can Compensate for IgSF11 Deficiency by Associating with the Scaffold Protein PSD-95 during Osteoclast Differentiation. International Journal of Molecular Sciences. 21. PMID 32290171 DOI: 10.3390/Ijms21072646  0.413
2020 Kim H, Takegahara N, Walsh MC, Middleton SA, Yu J, Shirakawa J, Ueda J, Fujihara Y, Ikawa M, Ishii M, Kim J, Choi Y. IgSF11 regulates osteoclast differentiation through association with the scaffold protein PSD-95. Bone Research. 8: 5. PMID 32047704 DOI: 10.1038/S41413-019-0080-9  0.462
2019 Kim H, Walsh MC, Yu J, Laskoski P, Takigawa K, Takegahara N, Choi Y. Methylosome protein 50 associates with the purinergic receptor P2X5 and is involved in osteoclast maturation. Febs Letters. PMID 31432503 DOI: 10.1002/1873-3468.13581  0.407
2019 Shirakawa J, Takegahara N, Kim H, Lee SH, Sato K, Yamagishi S, Choi Y. Flrt2 is involved in fine-tuning of osteoclast multinucleation. Bmb Reports. PMID 31383250  0.38
2019 Xia Y, Liu N, Xie X, Bi G, Ba H, Li L, Zhang J, Deng X, Yao Y, Tang Z, Yin B, Wang J, Jiang K, Li Z, Choi Y, et al. The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion. Autophagy. PMID 30681394 DOI: 10.1080/15548627.2019.1569916  0.376
2019 Shirakawa J, Takegahara N, Kim H, Lee SH, Sato K, Yamagishi S, Choi Y. Flrt2 is involved in fine-tuning of osteoclast multinucleation. Journal of Biochemistry and Molecular Biology. 52: 514-519. DOI: 10.5483/Bmbrep.2019.52.8.116  0.478
2018 Navet B, Vargas-Franco JW, Gama A, Amiaud J, Choi Y, Yagita H, Mueller CG, Rédini F, Heymann D, Castaneda B, Lézot F. Maternal RANKL Reduces the Osteopetrotic Phenotype of Null Mutant Mouse Pups. Journal of Clinical Medicine. 7. PMID 30413057 DOI: 10.3390/Jcm7110426  0.329
2018 Kim H, Kajikawa T, Walsh MC, Takegahara N, Jeong YH, Hajishengallis G, Choi Y. The purinergic receptor P2X5 contributes to bone loss in experimental periodontitis. Bmb Reports. PMID 30103845  0.33
2018 Jin SH, Kim H, Gu DR, Park KH, Lee YR, Choi Y, Lee SH. Actin-binding LIM Protein 1 Regulates Receptor Activator of NF-κB Ligand-Mediated Osteoclast Differentiation and Motility. Bmb Reports. PMID 29921413 DOI: 10.5483/Bmbrep.2018.51.7.106  0.478
2018 Fang J, Muto T, Kleppe M, Bolanos LC, Hueneman KM, Walker CS, Sampson L, Wellendorf AM, Chetal K, Choi K, Salomonis N, Choi Y, Zheng Y, Cancelas JA, Levine RL, et al. TRAF6 Mediates Basal Activation of NF-κB Necessary for Hematopoietic Stem Cell Homeostasis. Cell Reports. 22: 1250-1262. PMID 29386112 DOI: 10.1016/J.Celrep.2018.01.013  0.391
2018 Walsh MC, Takegahara N, Kim H, Choi Y. Updating osteoimmunology: regulation of bone cells by innate and adaptive immunity. Nature Reviews. Rheumatology. PMID 29323344 DOI: 10.1038/Nrrheum.2017.213  0.434
2018 Kim H, Kajikawa T, Walsh MC, Takegahara N, Jeong YH, Hajishengallis G, Choi Y. The purinergic receptor P2X5 contributes to bone loss in experimental periodontitis. Journal of Biochemistry and Molecular Biology. 51: 468-473. DOI: 10.5483/Bmbrep.2018.51.9.126  0.433
2018 Choi Y. Osteoclast Maturation And Inflammation Osteoporosis and Sarcopenia. 4. DOI: 10.1016/J.Afos.2018.11.026  0.327
2017 Ramaswamy G, Fong J, Brewer N, Kim H, Zhang D, Choi Y, Kaplan FS, Shore EM. Ablation of Gsα signaling in osteoclast progenitor cells adversely affects skeletal bone maintenance. Bone. PMID 29183785 DOI: 10.1016/J.Bone.2017.11.019  0.432
2017 Lan P, Fan Y, Zhao Y, Lou X, Monsour HP, Zhang X, Choi Y, Dou Y, Ishii N, Ghobrial RM, Xiao X, Li XC. TNF superfamily receptor OX40 triggers invariant NKT cell pyroptosis and liver injury. The Journal of Clinical Investigation. PMID 28436935 DOI: 10.1172/Jci91075  0.414
2017 Han D, Walsh MC, Kim KS, Hong SW, Lee J, Yi J, Rivas G, Choi Y, Surh CD. Dendritic cell expression of the signaling molecule TRAF6 is required for immune tolerance in the lung. International Immunology. PMID 28338920 DOI: 10.1093/Intimm/Dxx011  0.334
2017 Ramaswamy G, Kim H, Zhang D, Lounev V, Wu JY, Choi Y, Kaplan FS, Pignolo RJ, Shore EM. Gsα Controls Cortical Bone Quality by Regulating Osteoclast Differentiation via cAMP/PKA and β-Catenin Pathways. Scientific Reports. 7: 45140. PMID 28338087 DOI: 10.1038/Srep45140  0.42
2017 Kim H, Walsh MC, Takegahara N, Middleton SA, Shin HI, Kim J, Choi Y. The purinergic receptor P2X5 regulates inflammasome activity and hyper-multinucleation of murine osteoclasts. Scientific Reports. 7: 196. PMID 28298636 DOI: 10.1038/S41598-017-00139-2  0.424
2016 Yu J, Yun H, Shin B, Kim Y, Park ES, Choi S, Yu J, Amarasekara DS, Kim S, Inoue JI, Walsh MC, Choi Y, Takami M, Rho J. Interaction of Tumor Necrosis Factor Receptor-Associated Factor 6 (TRAF6) and Vav3 in The Receptor Activator of Nuclear Factor κB (RANK) Signaling Complex Enhances Osteoclastogenesis. The Journal of Biological Chemistry. PMID 27507811 DOI: 10.1074/Jbc.M116.728303  0.37
2016 Huh JE, Shin JH, Jang ES, Park SJ, Park DR, Ko R, Seo DH, Kim HS, Lee SH, Choi Y, Kim HS, Lee SY. Sirtuin 3 (SIRT3) maintains bone homeostasis by regulating AMPK-PGC-1β axis in mice. Scientific Reports. 6: 22511. PMID 26928655 DOI: 10.1038/Srep22511  0.43
2016 Lin J, Yang L, Silva HM, Trzeciak A, Choi Y, Schwab SR, Dustin ML, Lafaille JJ. Increased generation of Foxp3(+) regulatory T cells by manipulating antigen presentation in the thymus. Nature Communications. 7: 10562. PMID 26923114 DOI: 10.1038/Ncomms10562  0.377
2015 Takegahara N, Kim H, Mizuno H, Sakaue-Sawano A, Miyawaki A, Tomura M, Kanagawa O, Ishii M, Choi Y. Involvement of receptor activator of nuclear factor kappa-B ligand-induced incomplete cytokinesis in polyploidization of osteoclasts. The Journal of Biological Chemistry. PMID 26670608 DOI: 10.1074/Jbc.M115.677427  0.5
2015 Richard AC, Tan C, Hawley ET, Gomez-Rodriguez J, Goswami R, Yang XP, Cruz AC, Penumetcha P, Hayes ET, Pelletier M, Gabay O, Walsh M, Ferdinand JR, Keane-Myers A, Choi Y, et al. Correction: The TNF-Family Ligand TL1A and Its Receptor DR3 Promote T Cell-Mediated Allergic Immunopathology by Enhancing Differentiation and Pathogenicity of IL-9-Producing T Cells. Journal of Immunology (Baltimore, Md. : 1950). 195: 5839-40. PMID 26637663 DOI: 10.4049/jimmunol.1502026  0.3
2015 Lee JE, Walsh MC, Hoehn KL, James DE, Wherry EJ, Choi Y. Acetyl CoA Carboxylase 2 Is Dispensable for CD8+ T Cell Responses. Plos One. 10: e0137776. PMID 26367121 DOI: 10.1371/Journal.Pone.0137776  0.385
2015 Walsh MC, Lee J, Choi Y. Tumor necrosis factor receptor- associated factor 6 (TRAF6) regulation of development, function, and homeostasis of the immune system. Immunological Reviews. 266: 72-92. PMID 26085208 DOI: 10.1111/Imr.12302  0.463
2015 Lin J, Lee D, Choi Y, Lee SY. The scaffold protein RACK1 mediates the RANKL-dependent activation of p38 MAPK in osteoclast precursors. Science Signaling. 8: ra54. PMID 26038599 DOI: 10.1126/Scisignal.2005867  0.436
2015 Jeong BC, Kim TS, Kim HS, Lee SH, Choi Y. Transmembrane protein 64 reciprocally regulates osteoblast and adipocyte differentiation by modulating Wnt/β-catenin signaling. Bone. 78: 165-73. PMID 25979161 DOI: 10.1016/J.Bone.2015.05.009  0.431
2015 Ko R, Park JH, Ha H, Choi Y, Lee SY. Glycogen synthase kinase 3β ubiquitination by TRAF6 regulates TLR3-mediated pro-inflammatory cytokine production. Nature Communications. 6: 6765. PMID 25828701 DOI: 10.1038/Ncomms7765  0.365
2015 Richard AC, Tan C, Hawley ET, Gomez-Rodriguez J, Goswami R, Yang XP, Cruz AC, Penumetcha P, Hayes ET, Pelletier M, Gabay O, Walsh M, Ferdinand JR, Keane-Myers A, Choi Y, et al. The TNF-family ligand TL1A and its receptor DR3 promote T cell-mediated allergic immunopathology by enhancing differentiation and pathogenicity of IL-9-producing T cells. Journal of Immunology (Baltimore, Md. : 1950). 194: 3567-82. PMID 25786692 DOI: 10.4049/Jimmunol.1401220  0.403
2015 Dong G, Wang Y, Xiao W, Pacios Pujado S, Xu F, Tian C, Xiao E, Choi Y, Graves DT. FOXO1 regulates dendritic cell activity through ICAM-1 and CCR7. Journal of Immunology (Baltimore, Md. : 1950). 194: 3745-55. PMID 25786691 DOI: 10.4049/Jimmunol.1401754  0.385
2015 Park ES, Choi S, Shin B, Yu J, Yu J, Hwang JM, Yun H, Chung YH, Choi JS, Choi Y, Rho J. Tumor necrosis factor (TNF) receptor-associated factor (TRAF)-interacting protein (TRIP) negatively regulates the TRAF2 ubiquitin-dependent pathway by suppressing the TRAF2-sphingosine 1-phosphate (S1P) interaction. The Journal of Biological Chemistry. 290: 9660-73. PMID 25716317 DOI: 10.1074/Jbc.M114.609685  0.427
2015 Wang Y, Dong G, Jeon HH, Elazizi M, La LB, Hameedaldeen A, Xiao E, Tian C, Alsadun S, Choi Y, Graves DT. FOXO1 mediates RANKL-induced osteoclast formation and activity. Journal of Immunology (Baltimore, Md. : 1950). 194: 2878-87. PMID 25694609 DOI: 10.4049/Jimmunol.1402211  0.469
2015 Han D, Walsh MC, Kim KS, Hong SW, Lee J, Yi J, Rivas G, Surh CD, Choi Y. Microbiota-independent ameliorative effects of antibiotics on spontaneous th2-associated pathology of the small intestine. Plos One. 10: e0118795. PMID 25689829 DOI: 10.1371/Journal.Pone.0118795  0.322
2015 Lézot F, Chesneau J, Navet B, Gobin B, Amiaud J, Choi Y, Yagita H, Castaneda B, Berdal A, Mueller CG, Rédini F, Heymann D. Skeletal consequences of RANKL-blocking antibody (IK22-5) injections during growth: mouse strain disparities and synergic effect with zoledronic acid. Bone. 73: 51-9. PMID 25532478 DOI: 10.1016/J.Bone.2014.12.011  0.354
2015 Lezot FP, Navet B, Choi Y, Yagita H, Berdal A, Mueller CG, Redini F, Heymann D. Abstract 3289: Skeletal consequences of bone resorption inhibitors (zoledronic acid and RANKL blocking antibody) injections during growth: mouse strain disparities and synergic effect Cancer Research. 75: 3289-3289. DOI: 10.1158/1538-7445.Am2015-3289  0.36
2015 Lee SH, Choi Y. Communication between the skeletal and immune systems Osteoporosis and Sarcopenia. 1: 81-91. DOI: 10.1016/J.Afos.2015.09.004  0.444
2014 Walsh MC, Choi Y. Biology of the RANKL-RANK-OPG System in Immunity, Bone, and Beyond. Frontiers in Immunology. 5: 511. PMID 25368616 DOI: 10.3389/Fimmu.2014.00511  0.459
2014 Walsh MC, Pearce EL, Cejas PJ, Lee J, Wang LS, Choi Y. IL-18 synergizes with IL-7 to drive slow proliferation of naive CD8 T cells by costimulating self-peptide-mediated TCR signals. Journal of Immunology (Baltimore, Md. : 1950). 193: 3992-4001. PMID 25200954 DOI: 10.4049/Jimmunol.1400396  0.371
2014 Kim JH, Kim K, Youn BU, Lee J, Kim I, Shin HI, Akiyama H, Choi Y, Kim N. Kruppel-like factor 4 attenuates osteoblast formation, function, and cross talk with osteoclasts. The Journal of Cell Biology. 204: 1063-74. PMID 24616223 DOI: 10.1083/Jcb.201308102  0.429
2014 Lee J, Walsh MC, Hoehn KL, James DE, Wherry EJ, Choi Y. Regulator of fatty acid metabolism, acetyl coenzyme a carboxylase 1, controls T cell immunity. Journal of Immunology (Baltimore, Md. : 1950). 192: 3190-9. PMID 24567531 DOI: 10.4049/Jimmunol.1302985  0.408
2014 Danzl NM, Jeong S, Choi Y, Alexandropoulos K. Identification of novel thymic epithelial cell subsets whose differentiation is regulated by RANKL and Traf6. Plos One. 9: e86129. PMID 24465914 DOI: 10.1371/Journal.Pone.0086129  0.362
2014 Hindi SM, Sato S, Choi Y, Kumar A. Distinct roles of TRAF6 at early and late stages of muscle pathology in the mdx model of Duchenne muscular dystrophy. Human Molecular Genetics. 23: 1492-505. PMID 24163132 DOI: 10.1093/Hmg/Ddt536  0.369
2013 Jenkinson SR, Williams JA, Jeon H, Zhang J, Nitta T, Ohigashi I, Kruhlak M, Zuklys S, Sharrow S, Adams A, Granger L, Choi Y, Siebenlist U, Bishop GA, Hollander GA, et al. TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development. Proceedings of the National Academy of Sciences of the United States of America. 110: 21107-12. PMID 24324158 DOI: 10.1073/Pnas.1314859111  0.431
2013 Muto G, Kotani H, Kondo T, Morita R, Tsuruta S, Kobayashi T, Luche H, Fehling HJ, Walsh M, Choi Y, Yoshimura A. TRAF6 is essential for maintenance of regulatory T cells that suppress Th2 type autoimmunity. Plos One. 8: e74639. PMID 24058613 DOI: 10.1371/Journal.Pone.0074639  0.431
2013 Bonito AJ, Aloman C, Fiel MI, Danzl NM, Cha S, Weinstein EG, Jeong S, Choi Y, Walsh MC, Alexandropoulos K. Medullary thymic epithelial cell depletion leads to autoimmune hepatitis. The Journal of Clinical Investigation. 123: 3510-24. PMID 23867620 DOI: 10.1172/Jci65414  0.408
2013 Han D, Walsh MC, Cejas PJ, Dang NN, Kim YF, Kim J, Charrier-Hisamuddin L, Chau L, Zhang Q, Bittinger K, Bushman FD, Turka LA, Shen H, Reizis B, Defranco AL, ... ... Choi Y, et al. Dendritic cell expression of the signaling molecule TRAF6 is critical for gut microbiota-dependent immune tolerance. Immunity. 38: 1211-22. PMID 23791643 DOI: 10.1016/J.Immuni.2013.05.012  0.424
2013 Kim H, Kim T, Jeong BC, Cho IT, Han D, Takegahara N, Negishi-Koga T, Takayanagi H, Lee JH, Sul JY, Prasad V, Lee SH, Choi Y. Tmem64 modulates calcium signaling during RANKL-mediated osteoclast differentiation. Cell Metabolism. 17: 249-60. PMID 23395171 DOI: 10.1016/J.Cmet.2013.01.002  0.358
2013 Cheng T, Choi Y, Finkel TH, Tsao PY, Ji MQ, Eisenberg RA. Tumor necrosis factor receptor-associated factor 1 influences KRN/I-Ag7 mouse arthritis autoantibody production. Journal of Clinical Immunology. 33: 759-66. PMID 23354839 DOI: 10.1007/S10875-013-9866-5  0.321
2012 Hindi SM, Paul PK, Dahiya S, Mishra V, Bhatnagar S, Kuang S, Choi Y, Kumar A. Reciprocal interaction between TRAF6 and notch signaling regulates adult myofiber regeneration upon injury. Molecular and Cellular Biology. 32: 4833-45. PMID 23028045 DOI: 10.1128/Mcb.00717-12  0.393
2012 Xiao X, Balasubramanian S, Liu W, Chu X, Wang H, Taparowsky EJ, Fu YX, Choi Y, Walsh MC, Li XC. OX40 signaling favors the induction of T(H)9 cells and airway inflammation. Nature Immunology. 13: 981-90. PMID 22842344 DOI: 10.1038/Ni.2390  0.388
2012 Pérez-Chacón G, Llobet D, Pardo C, Pindado J, Choi Y, Reed JC, Zapata JM. TNFR-associated factor 2 deficiency in B lymphocytes predisposes to chronic lymphocytic leukemia/small lymphocytic lymphoma in mice. Journal of Immunology (Baltimore, Md. : 1950). 189: 1053-61. PMID 22711886 DOI: 10.4049/Jimmunol.1200814  0.4
2012 Wang H, Chen Q, Lee SH, Choi Y, Johnson FB, Pignolo RJ. Impairment of osteoblast differentiation due to proliferation-independent telomere dysfunction in mouse models of accelerated aging. Aging Cell. 11: 704-13. PMID 22621437 DOI: 10.1111/J.1474-9726.2012.00838.X  0.378
2012 DeSelm CJ, Takahata Y, Warren J, Chappel JC, Khan T, Li X, Liu C, Choi Y, Kim YF, Zou W, Teitelbaum SL. IL-17 mediates estrogen-deficient osteoporosis in an Act1-dependent manner. Journal of Cellular Biochemistry. 113: 2895-902. PMID 22511335 DOI: 10.1002/Jcb.24165  0.348
2012 Paul PK, Bhatnagar S, Mishra V, Srivastava S, Darnay BG, Choi Y, Kumar A. The E3 ubiquitin ligase TRAF6 intercedes in starvation-induced skeletal muscle atrophy through multiple mechanisms. Molecular and Cellular Biology. 32: 1248-59. PMID 22290431 DOI: 10.1128/Mcb.06351-11  0.323
2012 Hess E, Duheron V, Decossas M, Lézot F, Berdal A, Chea S, Golub R, Bosisio MR, Bridal SL, Choi Y, Yagita H, Mueller CG. RANKL induces organized lymph node growth by stromal cell proliferation. Journal of Immunology (Baltimore, Md. : 1950). 188: 1245-54. PMID 22210913 DOI: 10.4049/Jimmunol.1101513  0.368
2011 Barrow AD, Raynal N, Andersen TL, Slatter DA, Bihan D, Pugh N, Cella M, Kim T, Rho J, Negishi-Koga T, Delaisse JM, Takayanagi H, Lorenzo J, Colonna M, Farndale RW, ... Choi Y, et al. OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice. The Journal of Clinical Investigation. 121: 3505-16. PMID 21841309 DOI: 10.1172/Jci45913  0.434
2011 West AP, Brodsky IE, Rahner C, Woo DK, Erdjument-Bromage H, Tempst P, Walsh MC, Choi Y, Shadel GS, Ghosh S. TLR signalling augments macrophage bactericidal activity through mitochondrial ROS. Nature. 472: 476-80. PMID 21525932 DOI: 10.1038/Nature09973  0.345
2011 Duheron V, Hess E, Duval M, Decossas M, Castaneda B, Klöpper JE, Amoasii L, Barbaroux JB, Williams IR, Yagita H, Penninger J, Choi Y, Lézot F, Groves R, Paus R, et al. Receptor activator of NF-kappaB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit. Proceedings of the National Academy of Sciences of the United States of America. 108: 5342-7. PMID 21402940 DOI: 10.1073/Pnas.1013054108  0.399
2010 Kim T, Ha H, Kim N, Park ES, Rho J, Kim EC, Lorenzo J, Choi Y, Lee SH. ATP6v0d2 deficiency increases bone mass, but does not influence ovariectomy-induced bone loss. Biochemical and Biophysical Research Communications. 403: 73-8. PMID 21040703 DOI: 10.1016/J.Bbrc.2010.10.117  0.4
2010 Ramón HE, Cejas PJ, LaRosa D, Rahman A, Harris JE, Zhang J, Hunter C, Choi Y, Turka LA. EGR-2 is not required for in vivo CD4 T cell mediated immune responses. Plos One. 5: e12904. PMID 20886122 DOI: 10.1371/Journal.Pone.0012904  0.437
2010 Liu X, Karnell JL, Yin B, Zhang R, Zhang J, Li P, Choi Y, Maltzman JS, Pear WS, Bassing CH, Turka LA. Distinct roles for PTEN in prevention of T cell lymphoma and autoimmunity in mice. The Journal of Clinical Investigation. 120: 2497-507. PMID 20516645 DOI: 10.1172/Jci42382  0.411
2010 Cejas PJ, Walsh MC, Pearce EL, Han D, Harms GM, Artis D, Turka LA, Choi Y. TRAF6 inhibits Th17 differentiation and TGF-beta-mediated suppression of IL-2. Blood. 115: 4750-7. PMID 20351308 DOI: 10.1182/Blood-2009-09-242768  0.385
2010 Beleut M, Rajaram RD, Caikovski M, Ayyanan A, Germano D, Choi Y, Schneider P, Brisken C. Two distinct mechanisms underlie progesterone-induced proliferation in the mammary gland Proceedings of the National Academy of Sciences of the United States of America. 107: 2989-2994. PMID 20133621 DOI: 10.1073/Pnas.0915148107  0.388
2010 Kim JH, Kim K, Jin HM, Song I, Youn BU, Lee SH, Choi Y, Kim N. Negative feedback control of osteoclast formation through ubiquitin-mediated down-regulation of NFATc1. The Journal of Biological Chemistry. 285: 5224-31. PMID 20037154 DOI: 10.1074/Jbc.M109.042812  0.38
2009 Sonawane SB, Kim JI, Lee MK, Lee SH, Duff PE, Moore DJ, Lian MM, Deng S, Choi Y, Yeh H, Caton AJ, Markmann JF. GITR Blockade Facilitates Treg Mediated Allograft Survival. Transplantation. 88: 1169-77. PMID 19935370 DOI: 10.1097/Tp.0B013E3181Ba6F85  0.42
2009 Ha H, Han D, Choi Y. TRAF-mediated TNFR-family signaling. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit11.9D. PMID 19918944 DOI: 10.1002/0471142735.im1109ds87  0.318
2009 Kim T, Ha HI, Kim N, Yi O, Lee SH, Choi Y. Adrm1 interacts with Atp6v0d2 and regulates osteoclast differentiation. Biochemical and Biophysical Research Communications. 390: 585-90. PMID 19818731 DOI: 10.1016/J.Bbrc.2009.10.010  0.428
2009 Choi Y, Arron JR, Townsend MJ. Promising bone-related therapeutic targets for rheumatoid arthritis. Nature Reviews. Rheumatology. 5: 543-8. PMID 19798028 DOI: 10.1038/Nrrheum.2009.175  0.354
2009 Zhao B, Takami M, Yamada A, Wang X, Koga T, Hu X, Tamura T, Ozato K, Choi Y, Ivashkiv LB, Takayanagi H, Kamijo R. Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis. Nature Medicine. 15: 1066-71. PMID 19718038 DOI: 10.1038/Nm.2007  0.473
2009 Pearce EL, Walsh MC, Cejas PJ, Harms GM, Shen H, Wang LS, Jones RG, Choi Y. Enhancing CD8 T-cell memory by modulating fatty acid metabolism. Nature. 460: 103-7. PMID 19494812 DOI: 10.1038/Nature08097  0.421
2009 Wojtusciszyn A, Andres A, Morel P, Charvier S, Armanet M, Toso C, Choi Y, Bosco D, Berney T. Immunomodulation by blockade of the TRANCE co-stimulatory pathway in murine allogeneic islet transplantation. Transplant International : Official Journal of the European Society For Organ Transplantation. 22: 931-9. PMID 19453995 DOI: 10.1111/J.1432-2277.2009.00892.X  0.387
2009 Kim T, Kim K, Lee SH, So HS, Lee J, Kim N, Choi Y. Identification of LRRc17 as a negative regulator of receptor activator of NF-kappaB ligand (RANKL)-induced osteoclast differentiation. The Journal of Biological Chemistry. 284: 15308-16. PMID 19336404 DOI: 10.1074/Jbc.M807722200  0.506
2009 Kobayashi T, Kim TS, Jacob A, Walsh MC, Kadono Y, Fuentes-Pananá E, Yoshioka T, Yoshimura A, Yamamoto M, Kaisho T, Akira S, Monroe JG, Choi Y. TRAF6 is required for generation of the B-1a B cell compartment as well as T cell-dependent and -independent humoral immune responses. Plos One. 4: e4736. PMID 19270748 DOI: 10.1371/Journal.Pone.0004736  0.428
2009 Kim H, Choi HK, Shin JH, Kim KH, Huh JY, Lee SA, Ko CY, Kim HS, Shin HI, Lee HJ, Jeong D, Kim N, Choi Y, Lee SY. Selective inhibition of RANK blocks osteoclast maturation and function and prevents bone loss in mice. The Journal of Clinical Investigation. 119: 813-25. PMID 19258703 DOI: 10.1172/Jci36809  0.436
2009 Choi Y, Walsh MC, Arron JR. Breaking into bone biology: target practice. Nature Medicine. 15: 144-5. PMID 19197288 DOI: 10.1038/Nm0209-144  0.34
2008 Walsh MC, Kim GK, Maurizio PL, Molnar EE, Choi Y. TRAF6 autoubiquitination-independent activation of the NFkappaB and MAPK pathways in response to IL-1 and RANKL. Plos One. 3: e4064. PMID 19112497 DOI: 10.1371/Journal.Pone.0004064  0.382
2008 Yoshida R, Takaesu G, Yoshida H, Okamoto F, Yoshioka T, Choi Y, Akira S, Kawai T, Yoshimura A, Kobayashi T. TRAF6 and MEKK1 play a pivotal role in the RIG-I-like helicase antiviral pathway. The Journal of Biological Chemistry. 283: 36211-20. PMID 18984593 DOI: 10.1074/Jbc.M806576200  0.325
2008 Lee SH, Kim TS, Choi Y, Lorenzo J. Osteoimmunology: cytokines and the skeletal system. Bmb Reports. 41: 495-510. PMID 18682033 DOI: 10.5483/Bmbrep.2008.41.7.495  0.403
2008 Lorenzo J, Horowitz M, Choi Y. Osteoimmunology: interactions of the bone and immune system. Endocrine Reviews. 29: 403-40. PMID 18451259 DOI: 10.1210/Er.2007-0038  0.401
2008 Lee SH, Kim T, Jeong D, Kim N, Choi Y. The tec family tyrosine kinase Btk Regulates RANKL-induced osteoclast maturation. The Journal of Biological Chemistry. 283: 11526-34. PMID 18281276 DOI: 10.1074/Jbc.M708935200  0.513
2008 Lee SH, Kim T, Park ES, Yang S, Jeong D, Choi Y, Rho J. NHE10, an osteoclast-specific member of the Na+/H+ exchanger family, regulates osteoclast differentiation and survival [corrected]. Biochemical and Biophysical Research Communications. 369: 320-6. PMID 18269914 DOI: 10.1016/J.Bbrc.2008.01.168  0.368
2008 Yoon K, Jung EJ, Lee SR, Kim J, Choi Y, Lee SY. TRAF6 deficiency promotes TNF-induced cell death through inactivation of GSK3β Cell Death and Differentiation. 15: 730-738. PMID 18202703 DOI: 10.1038/Sj.Cdd.4402304  0.483
2008 King CG, Buckler JL, Kobayashi T, Hannah JR, Bassett G, Kim T, Pearce EL, Kim GG, Turka LA, Choi Y. Cutting edge: requirement for TRAF6 in the induction of T cell anergy. Journal of Immunology (Baltimore, Md. : 1950). 180: 34-8. PMID 18097000 DOI: 10.4049/Jimmunol.180.1.34  0.425
2008 Pignolo RJ, Suda RK, McMillan EA, Shen J, Lee SH, Choi Y, Wright AC, Johnson FB. Defects in telomere maintenance molecules impair osteoblast differentiation and promote osteoporosis. Aging Cell. 7: 23-31. PMID 18028256 DOI: 10.1111/J.1474-9726.2007.00350.X  0.361
2008 Kim K, Lee SH, Ha Kim J, Choi Y, Kim N. NFATc1 induces osteoclast fusion via up-regulation of Atp6v0d2 and the dendritic cell-specific transmembrane protein (DC-STAMP). Molecular Endocrinology (Baltimore, Md.). 22: 176-85. PMID 17885208 DOI: 10.1210/Me.2007-0237  0.471
2007 Lee J, Lee SH, Choi Y, Kim N. The negative role of IdS in osteoclastogenesis. Advances in Experimental Medicine and Biology. 602: 23-31. PMID 17966384 DOI: 10.1007/978-0-387-72009-8_3  0.35
2007 Park ES, Choi S, Kim JM, Jeong Y, Choe J, Park CS, Choi Y, Rho J. Early embryonic lethality caused by targeted disruption of the TRAF-interacting protein (TRIP) gene. Biochemical and Biophysical Research Communications. 363: 971-7. PMID 17927961 DOI: 10.1016/J.Bbrc.2007.09.103  0.437
2007 Lee SY, Choi Y. TRAF1 and its biological functions. Advances in Experimental Medicine and Biology. 597: 25-31. PMID 17633014 DOI: 10.1007/978-0-387-70630-6_2  0.339
2007 Hamazaki Y, Fujita H, Kobayashi T, Choi Y, Scott HS, Matsumoto M, Minato N. Medullary thymic epithelial cells expressing Aire represent a unique lineage derived from cells expressing claudin. Nature Immunology. 8: 304-11. PMID 17277780 DOI: 10.1038/Ni1438  0.375
2007 Kim JM, Min SK, Kim H, Kang HK, Jung SY, Lee SH, Choi Y, Roh S, Jeong D, Min BM. Vacuolar-type H+-ATPase-mediated acidosis promotes in vitro osteoclastogenesis via modulation of cell migration. International Journal of Molecular Medicine. 19: 393-400. PMID 17273786 DOI: 10.3892/Ijmm.19.3.393  0.4
2007 Zhu J, Garrett R, Jung Y, Zhang Y, Kim N, Wang J, Joe GJ, Hexner E, Choi Y, Taichman RS, Emerson SG. Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells. Blood. 109: 3706-12. PMID 17227831 DOI: 10.1182/Blood-2006-08-041384  0.395
2006 Lee SH, Rho J, Jeong D, Sul JY, Kim T, Kim N, Kang JS, Miyamoto T, Suda T, Lee SK, Pignolo RJ, Koczon-Jaremko B, Lorenzo J, Choi Y. v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation. Nature Medicine. 12: 1403-9. PMID 17128270 DOI: 10.1038/Nm1514  0.425
2006 Gelman AE, LaRosa DF, Zhang J, Walsh PT, Choi Y, Sunyer JO, Turka LA. The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4+ T cells and enables CpG oligodeoxynucleotide-mediated costimulation. Immunity. 25: 783-93. PMID 17055754 DOI: 10.1016/J.Immuni.2006.08.023  0.431
2006 Lee SK, Kadono Y, Okada F, Jacquin C, Koczon-Jaremko B, Gronowicz G, Adams DJ, Aguila HL, Choi Y, Lorenzo JA. T lymphocyte-deficient mice lose trabecular bone mass with ovariectomy. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 21: 1704-12. PMID 17002560 DOI: 10.1359/Jbmr.060726  0.402
2006 Mochizuki A, Takami M, Kawawa T, Suzumoto R, Sasaki T, Shiba A, Tsukasaki H, Zhao B, Yasuhara R, Suzawa T, Miyamoto Y, Choi Y, Kamijo R. Identification and characterization of the precursors committed to osteoclasts induced by TNF-related activation-induced cytokine/receptor activator of NF-kappa B ligand. Journal of Immunology (Baltimore, Md. : 1950). 177: 4360-8. PMID 16982870 DOI: 10.4049/Jimmunol.177.7.4360  0.472
2006 Buckler JL, Walsh PT, Porrett PM, Choi Y, Turka LA. Cutting edge: T cell requirement for CD28 costimulation is due to negative regulation of TCR signals by PTEN. Journal of Immunology (Baltimore, Md. : 1950). 177: 4262-6. PMID 16982858 DOI: 10.4049/Jimmunol.177.7.4262  0.413
2006 King CG, Kobayashi T, Cejas PJ, Kim T, Yoon K, Kim GK, Chiffoleau E, Hickman SP, Walsh PT, Turka LA, Choi Y. TRAF6 is a T cell-intrinsic negative regulator required for the maintenance of immune homeostasis. Nature Medicine. 12: 1088-92. PMID 16921377 DOI: 10.1038/Nm1449  0.457
2006 Walsh MC, Kim N, Kadono Y, Rho J, Lee SY, Lorenzo J, Choi Y. Osteoimmunology: interplay between the immune system and bone metabolism. Annual Review of Immunology. 24: 33-63. PMID 16551243 DOI: 10.1146/Annurev.Immunol.24.021605.090646  0.402
2006 Lee J, Kim K, Kim JH, Jin HM, Choi HK, Lee SH, Kook H, Kim KK, Yokota Y, Lee SY, Choi Y, Kim N. Id helix-loop-helix proteins negatively regulate TRANCE-mediated osteoclast differentiation. Blood. 107: 2686-93. PMID 16322470 DOI: 10.1182/Blood-2005-07-2798  0.469
2006 Chung YW, Kim TS, Lee SY, Lee SH, Choi Y, Kim N, Min BM, Jeong DW, Kim IY. Selenite-induced apoptosis of osteoclasts mediated by the mitochondrial pathway. Toxicology Letters. 160: 143-50. PMID 16111838 DOI: 10.1016/J.Toxlet.2005.06.019  0.341
2005 Spohn G, Schwarz K, Maurer P, Illges H, Rajasekaran N, Choi Y, Jennings GT, Bachmann MF. Protection against osteoporosis by active immunization with TRANCE/RANKL displayed on virus-like particles. Journal of Immunology (Baltimore, Md. : 1950). 175: 6211-8. PMID 16237119 DOI: 10.4049/Jimmunol.175.9.6211  0.411
2005 Kim N, Kadono Y, Takami M, Lee J, Lee SH, Okada F, Kim JH, Kobayashi T, Odgren PR, Nakano H, Yeh WC, Lee SK, Lorenzo JA, Choi Y. Osteoclast differentiation independent of the TRANCE-RANK-TRAF6 axis. The Journal of Experimental Medicine. 202: 589-95. PMID 16147974 DOI: 10.1084/Jem.20050978  0.468
2005 Kim K, Kim JH, Lee J, Jin HM, Lee SH, Fisher DE, Kook H, Kim KK, Choi Y, Kim N. Nuclear factor of activated T cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesis. The Journal of Biological Chemistry. 280: 35209-16. PMID 16109714 DOI: 10.1074/Jbc.M505815200  0.438
2005 Choi Y. Role of TRAF6 in the immune system Advances in Experimental Medicine and Biology. 560: 77-82. PMID 15932023 DOI: 10.1007/0-387-24180-9_11  0.387
2005 Li H, Cuartas E, Cui W, Choi Y, Crawford TD, Hua ZK, Kobayashi KS, Flavell RA, Vignery A. IL-1 receptor-associated kinase M is a central regulator of osteoclast differentiation and activation Journal of Experimental Medicine. 201: 1169-1177. PMID 15809356 DOI: 10.1084/Jem.20041444  0.427
2005 Kadono Y, Okada F, Perchonock C, Jang HD, Lee SY, Kim N, Choi Y. Strength of TRAF6 signalling determines osteoclastogenesis. Embo Reports. 6: 171-6. PMID 15678156 DOI: 10.1038/Sj.Embor.7400345  0.402
2005 Sun J, Walsh M, Villarino AV, Cervi L, Hunter CA, Choi Y, Pearce EJ. TLR ligands can activate dendritic cells to provide a MyD88-dependent negative signal for Th2 cell development. Journal of Immunology (Baltimore, Md. : 1950). 174: 742-51. PMID 15634894 DOI: 10.4049/Jimmunol.174.2.742  0.376
2004 Chen A, Xu H, Choi Y, Wang B, Zheng G. TRANCE counteracts FasL-mediated apoptosis of murine bone marrow-derived dendritic cells. Cellular Immunology. 231: 40-8. PMID 15919368 DOI: 10.1016/J.Cellimm.2004.11.005  0.396
2004 Kobayashi T, Walsh MC, Choi Y. The role of TRAF6 in signal transduction and the immune response. Microbes and Infection / Institut Pasteur. 6: 1333-8. PMID 15555541 DOI: 10.1016/J.Micinf.2004.09.001  0.411
2004 Zapata JM, Krajewska M, Morse HC, Choi Y, Reed JC. TNF receptor-associated factor (TRAF) domain and Bcl-2 cooperate to induce small B cell lymphoma/chronic lymphocytic leukemia in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 16600-5. PMID 15545599 DOI: 10.1073/Pnas.0407541101  0.386
2004 Mason NJ, Fiore J, Kobayashi T, Masek KS, Choi Y, Hunter CA. TRAF6-dependent mitogen-activated protein kinase activation differentially regulates the production of interleukin-12 by macrophages in response to Toxoplasma gondii. Infection and Immunity. 72: 5662-7. PMID 15385464 DOI: 10.1128/Iai.72.10.5662-5667.2004  0.346
2004 Gelman AE, Zhang J, Choi Y, Turka LA. Toll-like receptor ligands directly promote activated CD4+ T cell survival. Journal of Immunology (Baltimore, Md. : 1950). 172: 6065-73. PMID 15128790 DOI: 10.4049/Jimmunol.172.10.6065  0.433
2004 Guillonneau C, Louvet C, Renaudin K, Heslan JM, Heslan M, Tesson L, Vignes C, Guillot C, Choi Y, Turka LA, Cuturi MC, Anegon I, Josien R. The role of TNF-related activation-induced cytokine-receptor activating NF-kappa B interaction in acute allograft rejection and CD40L-independent chronic allograft rejection. Journal of Immunology (Baltimore, Md. : 1950). 172: 1619-29. PMID 14734743 DOI: 10.4049/Jimmunol.172.3.1619  0.429
2004 Eberl G, Marmon S, Sunshine MJ, Rennert PD, Choi Y, Littman DR. An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nature Immunology. 5: 64-73. PMID 14691482 DOI: 10.1038/Ni1022  0.339
2004 Cheng X, Kinosaki M, Takami M, Choi Y, Zhang H, Murali R. Disabling of receptor activator of nuclear factor-kappaB (RANK) receptor complex by novel osteoprotegerin-like peptidomimetics restores bone loss in vivo. The Journal of Biological Chemistry. 279: 8269-77. PMID 14679212 DOI: 10.1074/Jbc.M309690200  0.445
2004 Odgren PR, Kim N, MacKay CA, Mason-Savas A, Choi Y, Marks SC. The role of RANKL (TRANCE/TNFSF11), a tumor necrosis factor family member, in skeletal development: effects of gene knockout and transgenic rescue. Connective Tissue Research. 264-71. PMID 12952207  0.334
2004 Eshima K, Choi Y, Flavell RA. CD154-CD40-independent up-regulation of B7-2 on splenic antigen-presenting cells and efficient T cell priming by staphylococcal enterotoxin A. International Immunology. 15: 817-26. PMID 12807820 DOI: 10.1093/Intimm/Dxg080  0.356
2004 Zhu J, Zhang Y, Kim N, Choi Y, Joe G, Taichman R, Emerson SG. Osteoblasts Support Early B Lymphoiesis as well as Stem Cell Proliferation and Myelopoiesis: Identification of the Mammalian Cellular Analog of the Bursa of Fabricius. Blood. 104: 508-508. DOI: 10.1182/Blood.V104.11.508.508  0.414
2003 Chiffoleau E, Kobayashi T, Walsh MC, King CG, Walsh PT, Hancock WW, Choi Y, Turka LA. TNF receptor-associated factor 6 deficiency during hemopoiesis induces Th2-polarized inflammatory disease. Journal of Immunology (Baltimore, Md. : 1950). 171: 5751-9. PMID 14634083 DOI: 10.4049/Jimmunol.171.11.5751  0.458
2003 Padigel UM, Kim N, Choi Y, Farrell JP. TRANCE-RANK costimulation is required for IL-12 production and the initiation of a Th1-type response to Leishmania major infection in CD40L-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 171: 5437-41. PMID 14607948 DOI: 10.4049/Jimmunol.171.10.5437  0.356
2003 Kobayashi T, Walsh PT, Walsh MC, Speirs KM, Chiffoleau E, King CG, Hancock WW, Caamano JH, Hunter CA, Scott P, Turka LA, Choi Y. TRAF6 is a critical factor for dendritic cell maturation and development. Immunity. 19: 353-63. PMID 14499111 DOI: 10.1016/S1074-7613(03)00230-9  0.462
2003 Walsh MC, Choi Y. Biology of the TRANCE axis Cytokine & Growth Factor Reviews. 14: 251-263. PMID 12787563 DOI: 10.1016/S1359-6101(03)00027-3  0.45
2003 So H, Rho J, Jeong D, Park R, Fisher DE, Ostrowski MC, Choi Y, Kim N. Microphthalmia transcription factor and PU.1 synergistically induce the leukocyte receptor osteoclast-associated receptor gene expression. The Journal of Biological Chemistry. 278: 24209-16. PMID 12695521 DOI: 10.1074/Jbc.M302940200  0.398
2003 Odgren PR, Kim N, MacKay CA, Mason-Savas A, Choi Y, Marks SC. The role of RANKL (TRANCE/TNFSF11), a tumor necrosis factor family member, in skeletal development: effects of gene knockout and transgenic rescue. Connective Tissue Research. 44: 264-271. DOI: 10.1080/03008200390181753  0.445
2002 Arron JR, Walsh MC, Choi Y. TRAF-mediated TNFR-family signaling. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 11.9D. PMID 18432871 DOI: 10.1002/0471142735.Im1109Ds51  0.388
2002 Arron JR, Pewzner-Jung Y, Walsh MC, Kobayashi T, Choi Y. Regulation of the Subcellular Localization of Tumor Necrosis Factor Receptor–associated Factor (TRAF)2 by TRAF1 Reveals Mechanisms of TRAF2 Signaling Journal of Experimental Medicine. 196: 923-934. PMID 12370254 DOI: 10.1084/Jem.20020774  0.416
2002 Rho J, Altmann CR, Socci ND, Merkov L, Kim N, So H, Lee O, Takami M, Brivanlou AH, Choi Y. Gene expression profiling of osteoclast differentiation by combined suppression subtractive hybridization (SSH) and cDNA microarray analysis. Dna and Cell Biology. 21: 541-9. PMID 12215257 DOI: 10.1089/104454902320308915  0.417
2002 Ye H, Arron JR, Lamothe B, Cirilli M, Kobayashi T, Shevde NK, Segal D, Dzivenu OK, Vologodskaia M, Yim M, Du K, Singh S, Pike JW, Darnay BG, Choi Y, et al. Distinct molecular mechanism for initiating TRAF6 signalling. Nature. 418: 443-7. PMID 12140561 DOI: 10.1038/Nature00888  0.408
2002 Takami M, Kim N, Rho J, Choi Y. Stimulation by toll-like receptors inhibits osteoclast differentiation Journal of Immunology. 169: 1516-1523. PMID 12133979 DOI: 10.4049/jimmunol.169.3.1516  0.343
2002 Ouaaz F, Arron J, Zheng Y, Choi Y, Beg AA. Dendritic cell development and survival require distinct NF-kappaB subunits. Immunity. 16: 257-70. PMID 11869686 DOI: 10.1016/S1074-7613(02)00272-8  0.401
2002 Green EA, Choi Y, Flavell RA. Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals. Immunity. 16: 183-91. PMID 11869680 DOI: 10.1016/S1074-7613(02)00279-0  0.371
2002 Yaccoby S, Pearse RN, Johnson CL, Barlogie B, Choi Y, Epstein J. Myeloma interacts with the bone marrow microenvironment to induce osteoclastogenesis and is dependent on osteoclast activity. British Journal of Haematology. 116: 278-90. PMID 11841428 DOI: 10.1046/J.1365-2141.2002.03257.X  0.439
2002 Kim N, Takami M, Rho J, Josien R, Choi Y. A Novel Member of the Leukocyte Receptor Complex Regulates Osteoclast Differentiation Journal of Experimental Medicine. 195: 201-209. PMID 11805147 DOI: 10.1084/Jem.20011681  0.5
2002 Harmsen A, Kusser K, Hartson L, Tighe M, Sunshine MJ, Sedgwick JD, Choi Y, Littman DR, Randall TD. Cutting edge: organogenesis of nasal-associated lymphoid tissue (NALT) occurs independently of lymphotoxin-alpha (LT alpha) and retinoic acid receptor-related orphan receptor-gamma, but the organization of NALT is LT alpha dependent. Journal of Immunology (Baltimore, Md. : 1950). 168: 986-90. PMID 11801629 DOI: 10.4049/Jimmunol.168.3.986  0.352
2001 Odgren PR, Kim N, Van Wesenbeeck L, Mackay C, Mason-Savas A, Safadi FF, Popoff SN, Lengner C, Van-Hul W, Choi Y, Marks SC. Evidence that the rat osteopetrotic mutation toothless (tl) is not in the TNFSF11 (TRANCE, RANKL, ODF, OPGL) gene International Journal of Developmental Biology. 45: 853-859. PMID 11804028 DOI: 10.1387/Ijdb.11804028  0.384
2001 Kim YM, Kim YM, Lee YM, Kim HS, Kim JD, Choi Y, Kim KW, Lee SY, Kwon YG. TNF-related activation-induced cytokine (TRANCE) induces angiogenesis through the activation of Src and phospholipase C (PLC) in human endothelial cells. The Journal of Biological Chemistry. 277: 6799-805. PMID 11741951 DOI: 10.1074/Jbc.M109434200  0.366
2001 Rho J, Gong S, Kim N, Choi Y. TDAG51 is not essential for Fas/CD95 regulation and apoptosis in vivo Molecular and Cellular Biology. 21: 8365-8370. PMID 11713273 DOI: 10.1128/Mcb.21.24.8365-8370.2001  0.415
2001 Pettit AR, Ji H, von Stechow D, Müller R, Goldring SR, Choi Y, Benoist C, Gravallese EM. TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis. The American Journal of Pathology. 159: 1689-99. PMID 11696430 DOI: 10.1016/S0002-9440(10)63016-7  0.454
2001 Pearse RN, Sordillo EM, Yaccoby S, Wong BR, Liau DF, Colman N, Michaeli J, Epstein J, Choi Y. Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression Proceedings of the National Academy of Sciences of the United States of America. 98: 11581-11586. PMID 11562486 DOI: 10.1073/Pnas.201394498  0.459
2001 Arron JR, Vologodskaia M, Wong BR, Naramura M, Kim N, Gu H, Choi Y. A Positive Regulatory Role for Cbl Family Proteins in Tumor Necrosis Factor-related Activation-induced Cytokine (TRANCE) and CD40L-mediated Akt Activation Journal of Biological Chemistry. 276: 30011-30017. PMID 11406619 DOI: 10.1074/Jbc.M100414200  0.42
2000 Arron JR, Choi Y. Bone versus immune system Nature. 408: 535-536. PMID 11117729 DOI: 10.1038/35046196  0.435
2000 Cannons JL, Choi Y, Watts TH. Role of TNF receptor-associated factor 2 and p38 mitogen-activated protein kinase activation during 4-1BB-dependent immune response Journal of Immunology. 165: 6193-6204. PMID 11086053 DOI: 10.4049/Jimmunol.165.11.6193  0.447
2000 Kim D, Mebius RE, MacMicking JD, Jung S, Cupedo T, Castellanos Y, Rho J, Wong BR, Josien R, Kim N, Rennert PD, Choi Y. Regulation of peripheral lymph node genesis by the tumor necrosis factor family member TRANCE. The Journal of Experimental Medicine. 192: 1467-78. PMID 11085748 DOI: 10.1084/Jem.192.10.1467  0.336
2000 Kim N, Odgren PR, Kim D, Marks SC, Choi Y. Diverse roles of the tumor necrosis factor family member TRANCE in skeletal physiology revealed by TRANCE deficiency and partial rescue by a lymphocyte-expressed TRANCE transgene. Proceedings of the National Academy of Sciences of the United States of America. 97: 10905-10910. PMID 10984520 DOI: 10.1073/Pnas.200294797  0.445
2000 Lean JM, Matsuo K, Fox SW, Fuller K, Gibson FM, Draycott G, Wani MR, Bayley KE, Wong BR, Choi Y, Wagner EF, Chambers TJ. Osteoclast lineage commitment of bone marrow precursors through expression of membrane-bound TRANCE Bone. 27: 29-40. PMID 10865206 DOI: 10.1016/S8756-3282(00)00306-9  0.453
2000 Josien R, Li HL, Ingulli E, Sarma S, Wong BR, Vologodskaia M, Steinman RM, Choi Y. TRANCE, a tumor necrosis factor family member, enhances the longevity and adjuvant properties of dendritic cells in vivo. The Journal of Experimental Medicine. 191: 495-502. PMID 10662795 DOI: 10.1084/Jem.191.3.495  0.384
1999 Wong BR, Besser D, Kim N, Arron JR, Vologodskaia M, Hanafusa H, Choi Y. TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src. Molecular Cell. 4: 1041-9. PMID 10635328 DOI: 10.1016/S1097-2765(00)80232-4  0.336
1999 Kaufman DR, Choi Y. Signaling by tumor necrosis factor receptors: Pathways, paradigms and targets for therapeutic modulation International Reviews of Immunology. 18: 405-427. PMID 10626251 DOI: 10.3109/08830189909088491  0.322
1999 Wong BR, Josien R, Choi Y. TRANCE is a TNF family member that regulates dendritic cell and osteoclast function. Journal of Leukocyte Biology. 65: 715-724. PMID 10380891 DOI: 10.1002/Jlb.65.6.715  0.502
1999 Bachmann MF, Wong BR, Josien R, Steinman RM, Oxenius A, Choi Y. TRANCE, a tumor necrosis factor family member critical for CD40 ligand-independent T helper cell activation. The Journal of Experimental Medicine. 189: 1025-31. PMID 10190893 DOI: 10.1084/Jem.189.7.1025  0.409
1999 Wani MR, Fuller K, Kim NS, Choi Y, Chambers T. Prostaglandin E2 Cooperates With TRANCE in Osteoclast Induction From Hemopoietic Precursors: Synergistic Activation of Differentiation, Cell Spreading, and Fusion Endocrinology. 140: 1927-1935. PMID 10098533 DOI: 10.1210/Endo.140.4.6647  0.46
1999 Josien R, Wong B, Heslan J, Li H, Soulillou J-, Cuturi M, Steinman R, Choi Y. The Regulation Of Trance Expression On T Cells In Vitro And In Vivo During Acute Heart Allograft Rejection And Allograft Tolerance Transplantation. 67. DOI: 10.1097/00007890-199904150-00491  0.342
1998 Wong BR, Josien R, Lee SY, Vologodskaia M, Steinman RM, Choi Y. The TRAF family of signal transducers mediates NF-kappaB activation by the TRANCE receptor. The Journal of Biological Chemistry. 273: 28355-9. PMID 9774460 DOI: 10.1074/Jbc.273.43.28355  0.425
1998 Lee SY, Kaufman DR, Mora AL, Santana A, Boothby M, Choi Y. Stimulus-dependent synergism of the antiapoptotic tumor necrosis factor receptor-associated factor 2 (TRAF2) and nuclear factor κB pathways Journal of Experimental Medicine. 188: 1381-1384. PMID 9763618 DOI: 10.1084/Jem.188.7.1381  0.395
1998 Fuller K, Wong B, Fox S, Choi Y, Chambers TJ. TRANCE Is Necessary and Sufficient for Osteoblast-mediated Activation of Bone Resorption in Osteoclasts Journal of Experimental Medicine. 188: 997-1001. PMID 9730902 DOI: 10.1084/Jem.188.5.997  0.47
1998 Saoulli K, Lee SY, Cannons JL, Yeh WC, Santana A, Goldstein MD, Bangia N, DeBenedette MA, Mak TW, Choi Y, Watts TH. CD28-independent, TRAF2-dependent costimulation of resting T cells by 4- 1BB ligand Journal of Experimental Medicine. 187: 1849-1862. PMID 9607925 DOI: 10.1084/Jem.187.11.1849  0.432
1998 Hodtsev AS, Choi Y, Spanopoulou E, Posnett DN. Mycoplasma superantigen is a CDR3-dependent ligand for the T cell antigen receptor. The Journal of Experimental Medicine. 187: 319-27. PMID 9449712 DOI: 10.1084/Jem.187.3.319  0.325
1997 Wong BR, Josien R, Lee SY, Sauter B, Li HL, Steinman RM, Choi Y. TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine), a new TNF family member predominantly expressed in T cells, is a dendritic cell-specific survival factor. The Journal of Experimental Medicine. 186: 2075-80. PMID 9396779 DOI: 10.1084/Jem.186.12.2075  0.372
1997 Lee SY, Reichlin A, Santana A, Sokol KA, Nussenzweig MC, Choi Y. TRAF2 Is Essential for JNK but Not NF-κB Activation and Regulates Lymphocyte Proliferation and Survival Immunity. 7: 703-713. PMID 9390693 DOI: 10.1016/S1074-7613(00)80390-8  0.432
1997 Wong B, Arron J, Choi Y. T cell receptor signals enhance susceptibility to Fas-mediated apoptosis. Journal of Experimental Medicine. 186: 1939-1944. PMID 9382892 DOI: 10.1084/Jem.186.11.1939  0.438
1997 Wong BR, Rho J, Arron J, Robinson E, Orlinick J, Chao M, Kalachikov S, Cayani E, Bartlett FS, Frankel WN, Lee SY, Choi Y. TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells. The Journal of Biological Chemistry. 272: 25190-4. PMID 9312132 DOI: 10.1074/Jbc.272.40.25190  0.453
1997 Wong B, Choi Y. Pathways leading to cell death in T cells Current Opinion in Immunology. 9: 358-364. PMID 9203409 DOI: 10.1016/S0952-7915(97)80082-9  0.433
1997 Speiser DE, Lee SY, Wong B, Arron J, Santana A, Kong YY, Ohashi PS, Choi Y. A regulatory role for TRAF1 in antigen-induced apoptosis of T cells. The Journal of Experimental Medicine. 185: 1777-83. PMID 9151703 DOI: 10.1084/Jem.185.10.1777  0.493
1997 Kwon YG, Lee SY, Choi Y, Greengard P, Nairn AC. Cell cycle-dependent phosphorylation of mammalian protein phosphatase 1 by cdc2 kinase. Proceedings of the National Academy of Sciences of the United States of America. 94: 2168-73. PMID 9122166 DOI: 10.1073/Pnas.94.6.2168  0.341
1997 Wong B, Park CG, Choi Y. Identifying the molecular control of T-cell death; on the hunt for killer genes Seminars in Immunology. 9: 7-16. PMID 9106303 DOI: 10.1006/Smim.1996.0051  0.382
1997 Lee SY, Choi Y. TRAF-interacting protein (TRIP): A novel component of the tumor necrosis factor receptor (TNFR)- and CD30-TRAF signaling complexes that inhibits TRAF2-mediated NF-κB activation Journal of Experimental Medicine. 185: 1275-1285. PMID 9104814 DOI: 10.1084/Jem.185.7.1275  0.446
1996 Park CG, Lee SY, Kandala G, Lee SY, Choi Y. A Novel Gene Product that Couples TCR Signaling to Fas(CD95) Expression in Activation-Induced Cell Death Immunity. 4: 583-591. PMID 8673705 DOI: 10.1016/S1074-7613(00)80484-7  0.412
1996 Lee SY, Park CG, Choi Y. T cell receptor-dependent cell death of T cell hybridomas mediated by the CD30 cytoplasmic domain in association with tumor necrosis factor receptor-associated factors. Journal of Experimental Medicine. 183: 669-674. PMID 8627180 DOI: 10.1084/Jem.183.2.669  0.426
1996 Choi J, Lee SY, Choi Y. Identification of a Putative G Protein-Coupled Receptor Induced during Activation-Induced Apoptosis of T Cells Cellular Immunology. 168: 78-84. PMID 8599842 DOI: 10.1006/Cimm.1996.0051  0.439
1995 Yazdanbakhsh K, Choi JW, Li Y, Lau LF, Choi Y. Cyclosporin A blocks apoptosis by inhibiting the DNA binding activity of the transcription factor Nur77. Proceedings of the National Academy of Sciences of the United States of America. 92: 437-41. PMID 7831306 DOI: 10.1073/Pnas.92.2.437  0.414
1993 Marrack P, Winslow GM, Choi Y, Scherer M, Pullen A, White J, Kappler JW. The bacterial and mouse mammary tumor virus superantigens; two different families of proteins with the same functions Immunological Reviews. 79-92. PMID 8387458 DOI: 10.1111/J.1600-065X.1993.Tb01531.X  0.313
1993 Yazdanbakhsh K, Park CG, Winslow GM, Choi Y. Direct evidence for the role of COOH terminus of mouse mammary tumor virus superantigen in determining T cell receptor Vβ specificity Journal of Experimental Medicine. 178: 737-741. PMID 7688034 DOI: 10.1084/Jem.178.2.737  0.375
1992 Choi Y, Marrack P, Kappler JW. Structural analysis of a mouse mammary tumor virus superantigen. Journal of Experimental Medicine. 175: 847-852. PMID 1311018 DOI: 10.1084/Jem.175.3.847  0.378
1991 Choi Y, Kappler JW, Marrack P. A superantigen encoded in the open reading frame of the 3' long terminal repeat of mouse mammary tumour virus. Nature. 350: 203-7. PMID 1706480 DOI: 10.1038/350203A0  0.326
1990 Choi YW, Herman A, DiGiusto D, Wade T, Marrack P, Kappler J. Residues of the variable region of the T-cell-receptor beta-chain that interact with S. aureus toxin superantigens. Nature. 346: 471-3. PMID 2377208 DOI: 10.1038/346471A0  0.318
1990 Choi Y, Lafferty JA, Clements JR, Todd JK, Gelfand EW, Kappler J, Marrack P, Kotzin BL. Selective expansion of T cells expressing V beta 2 in toxic shock syndrome. The Journal of Experimental Medicine. 172: 981-4. PMID 2117641 DOI: 10.1084/Jem.172.3.981  0.353
1989 Choi YW, Kotzin B, Herron L, Callahan J, Marrack P, Kappler J. Interaction of Staphylococcus aureus toxin "superantigens" with human T cells. Proceedings of the National Academy of Sciences of the United States of America. 86: 8941-5. PMID 2479030 DOI: 10.1073/Pnas.86.22.8941  0.339
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