Anil K. Jaiswal - Publications

Affiliations: 
Toxicology University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Oncology, Cell Biology, Molecular Biology

117 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Long DJ, Gaikwad A, Multani A, Pathak S, Montgomery CA, Gonzalez FJ, Jaiswal AK. Retraction: Disruption of the NAD(P)H:Quinone Oxidoreductase 1 (NQO1) Gene in Mice Causes Myelogenous Hyperplasia. Cancer Research. 78: 6526. PMID 30442815 DOI: 10.1158/0008-5472.Can-18-2455  0.304
2018 Khatri R, Shah P, Guha R, Rassool FV, Tomkinson AE, Brodie A, Jaiswal AK. Retraction: Aromatase Inhibitor-mediated Downregulation of INrf2 (Keap1) Leads to Increased Nrf2 and Resistance in Breast Cancer. Molecular Cancer Therapeutics. 17: 2491. PMID 30389813 DOI: 10.1158/1535-7163.MCT-17-0310  0.543
2018 Kannan S, Jaiswal AK. Retraction: Low and High Dose UVB Regulation of Transcription Factor NF-E2-Related Factor 2. Cancer Research. 78: 6346. PMID 30385612 DOI: 10.1158/0008-5472.Can-18-2454  0.33
2017 Patrick BA, Jaiswal AK. Stress-induced NQO1 controls stability of C/EBPα against 20S proteasomal degradation to regulate p63 expression with implications in protection against chemical-induced skin cancer. Oncogene. PMID 28263979 DOI: 10.1038/Onc.2016.476  0.436
2017 Patrick BA, Gong X, Jaiswal AK. Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to 20S proteasomal degradation of p63 resulting in thinning of epithelium and chemical-induced skin cancer. Oncogene. PMID 28263975 DOI: 10.1038/Onc.2016.475  0.349
2017 Niture SK, Jain AK, Jaiswal AK. Retraction: Antioxidant-induced modification of INrf2 cysteine 151 and PKC-δ-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance. Journal of Cell Science. 130: 816. PMID 28202606 DOI: 10.1242/Jcs.202093  0.39
2017 Niture SK, Gnatt A, Jaiswal AK. Retraction: Oncogene PKCε controls INrf2-Nrf2 interaction in normal and cancer cells through phosphorylation of INrf2. Journal of Cell Science. 130: 815. PMID 28202605 DOI: 10.1242/Jcs.201954  0.302
2017 Kaspar JW, Niture SK, Jaiswal AK. Retraction: Antioxidant-induced INrf2 (Keap1) tyrosine 85 phosphorylation controls the nuclear export and degradation of the INrf2-Cul3-Rbx1 complex to allow normal Nrf2 activation and repression. Journal of Cell Science. 130: 814. PMID 28202604 DOI: 10.1242/jcs.201947  0.814
2017 Jain AK, Bloom DA, Jaiswal AK. Nuclear import and export signals in control of Nrf2. The Journal of Biological Chemistry. 292: 2052. PMID 28159765 DOI: 10.1074/Jbc.A117.502083  0.374
2017 Jain AK, Jaiswal AK. Phosphorylation of tyrosine 568 controls nuclear export of Nrf2. The Journal of Biological Chemistry. 292: 2051. PMID 28159764 DOI: 10.1074/Jbc.A117.511198  0.462
2017 Jain AK, Mahajan S, Jaiswal AK. Phosphorylation and dephosphorylation of tyrosine 141 regulate stability and degradation of INrf2. A NOVEL MECHANISM IN NRF2 ACTIVATION. The Journal of Biological Chemistry. 292: 2050. PMID 28159763 DOI: 10.1074/Jbc.A117.709854  0.472
2017 Niture SK, Jain AK, Shelton PM, Jaiswal AK. Src subfamily kinases regulate nuclear export and degradation of transcription factor Nrf2 to switch off Nrf2-mediated antioxidant activation of cytoprotective gene expression. The Journal of Biological Chemistry. 292: 2048. PMID 28159761 DOI: 10.1074/jbc.A117.255042  0.836
2016 Lapidus RG, Carter-Cooper BA, Sadowska M, Choi EY, Wonodi O, Muvarak N, Natarajan K, Pidugu LS, Jaiswal A, Toth EA, Rassool FV, Etemadi A, Sausville EA, Baer MR, Emadi A. Hydroxylated Dimeric Naphthoquinones Increase the Generation of Reactive Oxygen Species, Induce Apoptosis of Acute Myeloid Leukemia Cells and Are Not Substrates of the Multidrug Resistance Proteins ABCB1 and ABCG2. Pharmaceuticals (Basel, Switzerland). 9. PMID 26797621 DOI: 10.3390/Ph9010004  0.384
2016 Jain AK, Mahajan S, Jaiswal AK. Phosphorylation and dephosphorylation of tyrosine 141 regulate stability and degradation of INrf2. A novel mechanism in Nrf2 activation. The Journal of Biological Chemistry. 291: 1199. PMID 26773127 DOI: 10.1074/Jbc.A108.709854  0.472
2016 Niture SK, Jaiswal AK. Prothymosin-α mediates nuclear import of the INrf2/Cul3·Rbx1 complex to degrade nuclear Nrf2. The Journal of Biological Chemistry. 291: 1199. PMID 26773126 DOI: 10.1074/Jbc.A109.808084  0.377
2016 Niture SK, Jain AK, Shelton PM, Jaiswal AK. Src subfamily kinases regulate nuclear export and degradation of transcription factor Nrf2 to swtich off Nrf2-mediated antioxidant activation of cytoprotective gene expression. The Journal of Biological Chemistry. 291: 1199. PMID 26773125 DOI: 10.1074/Jbc.A111.255042  0.835
2015 Khatri R, Shah P, Guha R, Rassool FV, Tomkinson AE, Brodie A, Jaiswal AK. Aromatase Inhibitor-Mediated Downregulation of INrf2 (Keap1) Leads to Increased Nrf2 and Resistance in Breast Cancer. Molecular Cancer Therapeutics. 14: 1728-37. PMID 25976679 DOI: 10.1158/1535-7163.Mct-14-0672  0.651
2014 Niture SK, Khatri R, Jaiswal AK. Regulation of Nrf2-an update. Free Radical Biology & Medicine. 66: 36-44. PMID 23434765 DOI: 10.1016/J.Freeradbiomed.2013.02.008  0.785
2013 Xu J, Patrick BA, Jaiswal AK. NRH:quinone oxidoreductase 2 (NQO2) protein competes with the 20 S proteasome to stabilize transcription factor CCAAT enhancer-binding protein α (C/EBPα), leading to protection against γ radiation-induced myeloproliferative disease. The Journal of Biological Chemistry. 288: 34799-808. PMID 24142791 DOI: 10.1074/Jbc.M113.495580  0.374
2013 Niture SK, Gnatt A, Jaiswal AK. Oncogene PKCε controls INrf2-Nrf2 interaction in normal and cancer cells through phosphorylation of INrf2. Journal of Cell Science. 126: 5657-69. PMID 24127568 DOI: 10.1242/Jcs.133819  0.53
2013 Niture SK, Jaiswal AK. Nrf2-induced antiapoptotic Bcl-xL protein enhances cell survival and drug resistance. Free Radical Biology & Medicine. 57: 119-31. PMID 23275004 DOI: 10.1016/J.Freeradbiomed.2012.12.014  0.518
2013 Shelton P, Jaiswal AK. The transcription factor NF-E2-related factor 2 (Nrf2): a protooncogene? Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 414-23. PMID 23109674 DOI: 10.1096/Fj.12-217257  0.814
2013 Emadi A, Sadowska M, Carter-Cooper B, Wonodi O, Muvarak N, Rassool F, Jaiswal A, Baer MR, Lapidus RG, Sausville EA. Dimeric Naphthoquinones: Novel Anti-Leukemic Agents Modulating Cellular Redox Status Blood. 122: 1290-1290. DOI: 10.1182/Blood.V122.21.1290.1290  0.334
2013 Xu J, Jaiswal A. Abstract 834: NRH:quinone oxidoreductase 2 (NQO2) stabilization of C/EBPα against 20S proteasomal degradation leads to protection against radiation-induced myeloproliferative diseases. Cancer Research. 73: 834-834. DOI: 10.1158/1538-7445.Am2013-834  0.363
2013 Niture SK, Jaiswal AK. Abstract 601: Antioxidant inhibition of GSK-3β stabilizes anti-apoptotic factor Mcl-1 leading to decreased apoptosis and increased cell survival. Cancer Research. 73: 601-601. DOI: 10.1158/1538-7445.Am2013-601  0.453
2013 Patrick BA, Jaiswal AK. Abstract 4306: NAD(P)H:quinone oxidoreductase 1 (NQO1) regulates MAPK activation and cellular protection against chemical stress. Cancer Research. 73: 4306-4306. DOI: 10.1158/1538-7445.Am2013-4306  0.534
2012 Xu J, Jaiswal AK. NAD(P)H:quinone oxidoreductase 1 (NQO1) competes with 20S proteasome for binding with C/EBPα leading to its stabilization and protection against radiation-induced myeloproliferative disease. The Journal of Biological Chemistry. 287: 41608-18. PMID 23086932 DOI: 10.1074/Jbc.M112.387738  0.398
2012 Patrick BA, Das A, Jaiswal AK. NAD(P)H:quinone oxidoreductase 1 protects bladder epithelium against painful bladder syndrome in mice. Free Radical Biology & Medicine. 53: 1886-93. PMID 22985937 DOI: 10.1016/J.Freeradbiomed.2012.08.584  0.324
2012 Kaspar JW, Niture SK, Jaiswal AK. Antioxidant-induced INrf2 (Keap1) tyrosine 85 phosphorylation controls the nuclear export and degradation of the INrf2-Cul3-Rbx1 complex to allow normal Nrf2 activation and repression. Journal of Cell Science. 125: 1027-38. PMID 22448038 DOI: 10.1242/Jcs.097295  0.824
2012 Niture SK, Jaiswal AK. Nrf2 protein up-regulates antiapoptotic protein Bcl-2 and prevents cellular apoptosis. The Journal of Biological Chemistry. 287: 9873-86. PMID 22275372 DOI: 10.1074/Jbc.M111.312694  0.522
2012 Patrick BA, Jaiswal AK. Stress-induced NQO1 controls stability of C/EBPα against 20S proteasomal degradation to regulate p63 expression with implications in protection against chemical-induced skin cancer. Oncogene. 31: 4362-71. PMID 22249251 DOI: 10.1038/onc.2011.600  0.328
2012 Xu J, Jaiswal A. Abstract 3074: NAD(P)H:quinone oxidoreductase 1 stabilizes C/EBPα from 20S proteasomal degradation leading to protection against myeloproliferative disease Cancer Research. 72: 3074-3074. DOI: 10.1158/1538-7445.Am2012-3074  0.373
2012 Patrick BA, Jaiswal AK. Abstract 2217: Stress-induced NQO1 controls stability of C/EBPα against 20S proteasomal degradation to regulate p63 expression with implications in protection against chemical-induced skin cancer Cancer Research. 72: 2217-2217. DOI: 10.1158/1538-7445.Am2012-2217  0.441
2011 Niture SK, Jaiswal AK. Inhibitor of Nrf2 (INrf2 or Keap1) protein degrades Bcl-xL via phosphoglycerate mutase 5 and controls cellular apoptosis. The Journal of Biological Chemistry. 286: 44542-56. PMID 22072718 DOI: 10.1074/Jbc.M111.275073  0.403
2011 Niture SK, Jain AK, Shelton PM, Jaiswal AK. Src subfamily kinases regulate nuclear export and degradation of transcription factor Nrf2 to switch off Nrf2-mediated antioxidant activation of cytoprotective gene expression Journal of Biological Chemistry. 286: 28821-28832. PMID 21690096 DOI: 10.1074/Jbc.M111.255042  0.84
2011 Kaspar JW, Jaiswal AK. Tyrosine phosphorylation controls nuclear export of Fyn, allowing Nrf2 activation of cytoprotective gene expression Faseb Journal. 25: 1076-1087. PMID 21097520 DOI: 10.1096/Fj.10-171553  0.838
2011 Niture SK, Jaiswal AK. INrf2 (Keap1) targets Bcl-2 degradation and controls cellular apoptosis Cell Death and Differentiation. 18: 439-451. PMID 20865015 DOI: 10.1038/cdd.2010.114  0.329
2010 Niture SK, Jaiswal AK. Hsp90 interaction with INrf2(Keap1) mediates stress-induced Nrf2 activation. The Journal of Biological Chemistry. 285: 36865-75. PMID 20864537 DOI: 10.1074/Jbc.M110.175802  0.403
2010 Kaspar JW, Jaiswal AK. An autoregulatory loop between Nrf2 and Cul3-Rbx1 controls their cellular abundance. The Journal of Biological Chemistry. 285: 21349-58. PMID 20452971 DOI: 10.1074/Jbc.M110.121863  0.83
2010 Shen J, Barrios RJ, Jaiswal AK. Inactivation of the quinone oxidoreductases NQO1 and NQO2 strongly elevates the incidence and multiplicity of chemically induced skin tumors. Cancer Research. 70: 1006-14. PMID 20103645 DOI: 10.1158/0008-5472.Can-09-2938  0.349
2010 Kaspar JW, Jaiswal AK. Antioxidant-induced phosphorylation of tyrosine 486 leads to rapid nuclear export of Bach1 that allows Nrf2 to bind to the antioxidant response element and activate defensive gene expression. The Journal of Biological Chemistry. 285: 153-62. PMID 19897490 DOI: 10.1074/Jbc.M109.040022  0.83
2010 Niture SK, Kaspar JW, Shen J, Jaiswal AK. Nrf2 signaling and cell survival. Toxicology and Applied Pharmacology. 244: 37-42. PMID 19538984 DOI: 10.1016/J.Taap.2009.06.009  0.835
2010 Niture SK, Jain AK, Jaiswal AK. Antioxidant-induced modification of INrf2 cysteine 151 and PKC-δ-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance (Journal of Cell Science (2010) 123, 11, (1969)) Journal of Cell Science. 123. DOI: 10.1242/Jcs.074286  0.466
2010 Khatri R, Niture SK, Jaiswal AK. Abstract 4131: Activation of PKC-delta inhibits apoptosis leading to mitomycin C resistance Cancer Research. 70: 4131-4131. DOI: 10.1158/1538-7445.Am10-4131  0.689
2010 Niture SK, Jain AK, Jaiswal AK. Abstract 4022: Antioxidant-induced modification of INrf2C151 and PKCdelta-mediated phosphorylation of Nrf2S40 are both required for stabilization and nuclear translation of Nrf2 and increased drug-resistance Cancer Research. 70: 4022-4022. DOI: 10.1158/1538-7445.Am10-4022  0.555
2010 Potla R, Jaiswal AK. Abstract 402: Role of NAD(P)H:quinone oxidoreductase 1 (NQO1) in chemotherapy induced myeloid leukemia Cancer Research. 70: 402-402. DOI: 10.1158/1538-7445.Am10-402  0.345
2010 Patrick BA, Kole L, Jaiswal AK. Abstract 318: NAD(P)H: quinone oxidoreductase 1 possesses a strong regulatory role in MAPK signaling pathways Cancer Research. 70: 318-318. DOI: 10.1158/1538-7445.Am10-318  0.519
2009 Niture SK, Jain AK, Jaiswal AK. Antioxidant-induced modification of INrf2 cysteine 151 and PKC-delta-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance. Journal of Cell Science. 122: 4452-64. PMID 19920073 DOI: 10.1242/Jcs.058537  0.579
2009 Shi S, Yoon DY, Hodge-Bell KC, Bebenek IG, Whitekus MJ, Zhang R, Cochran AJ, Huerta-Yepez S, Yim SH, Gonzalez FJ, Jaiswal AK, Hankinson O. The aryl hydrocarbon receptor nuclear translocator (Arnt) is required for tumor initiation by benzo[a]pyrene. Carcinogenesis. 30: 1957-61. PMID 19755658 DOI: 10.1093/Carcin/Bgp201  0.338
2009 Kaspar JW, Niture SK, Jaiswal AK. Nrf2:INrf2 (Keap1) signaling in oxidative stress. Free Radical Biology & Medicine. 47: 1304-9. PMID 19666107 DOI: 10.1016/J.Freeradbiomed.2009.07.035  0.839
2009 Levy S, Jaiswal AK, Forman HJ. The role of c-Jun phosphorylation in EpRE activation of phase II genes. Free Radical Biology & Medicine. 47: 1172-9. PMID 19666106 DOI: 10.1016/J.Freeradbiomed.2009.07.036  0.499
2009 Niture SK, Jaiswal AK. Prothymosin-alpha mediates nuclear import of the INrf2/Cul3 Rbx1 complex to degrade nuclear Nrf2. The Journal of Biological Chemistry. 284: 13856-68. PMID 19279002 DOI: 10.1074/Jbc.M808084200  0.45
2009 Iskander K, Barrios RJ, Jaiswal AK. NRH:quinone oxidoreductase 2-deficient mice are highly susceptible to radiation-induced B-cell lymphomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 1534-42. PMID 19223498 DOI: 10.1158/1078-0432.Ccr-08-1783  0.328
2008 Adikesavan AK, Unni E, Jaiswal AK. Overlapping signal sequences control nuclear localization and endoplasmic reticulum retention of GRP58. Biochemical and Biophysical Research Communications. 377: 407-12. PMID 18851953 DOI: 10.1016/J.Bbrc.2008.09.133  0.335
2008 Iskander K, Barrios RJ, Jaiswal AK. Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to radiation-induced myeloproliferative disease. Cancer Research. 68: 7915-22. PMID 18829548 DOI: 10.1158/0008-5472.Can-08-0766  0.316
2008 Jain AK, Mahajan S, Jaiswal AK. Phosphorylation and dephosphorylation of tyrosine 141 regulate stability and degradation of INrf2: a novel mechanism in Nrf2 activation. The Journal of Biological Chemistry. 283: 17712-20. PMID 18434303 DOI: 10.1074/Jbc.M709854200  0.613
2008 Wang W, Le WD, Pan T, Stringer JL, Jaiswal AK. Association of NRH:quinone oxidoreductase 2 gene promoter polymorphism with higher gene expression and increased susceptibility to Parkinson's disease. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 63: 127-34. PMID 18314446 DOI: 10.1093/Gerona/63.2.127  0.368
2008 Kondraganti SR, Jiang W, Jaiswal AK, Moorthy B. Persistent induction of hepatic and pulmonary phase II enzymes by 3-methylcholanthrene in rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 102: 337-44. PMID 18203689 DOI: 10.1093/Toxsci/Kfn007  0.357
2008 Li Y, Jaiswal AK. Human Antioxidant-Response-Element-Mediated Regulation of Type 1 NAD(P)H:quinone Oxidoreductase Gene Expression European Journal of Biochemistry. 226: 31-39. DOI: 10.1111/j.1432-1033.1994.00t31.x  0.33
2007 Ahn KS, Gong X, Sethi G, Chaturvedi MM, Jaiswal AK, Aggarwal BB. Deficiency of NRH:quinone oxidoreductase 2 differentially regulates TNF signaling in keratinocytes: up-regulation of apoptosis correlates with down-regulation of cell survival kinases. Cancer Research. 67: 10004-11. PMID 17942934 DOI: 10.1158/0008-5472.Can-07-2213  0.515
2007 Adikesavan AK, Jaiswal AK. Thioredoxin-like domains required for glucose regulatory protein 58 mediated reductive activation of mitomycin C leading to DNA cross-linking. Molecular Cancer Therapeutics. 6: 2719-27. PMID 17938265 DOI: 10.1158/1535-7163.Mct-07-0160  0.34
2007 Lee OH, Jain AK, Papusha V, Jaiswal AK. An auto-regulatory loop between stress sensors INrf2 and Nrf2 controls their cellular abundance. The Journal of Biological Chemistry. 282: 36412-20. PMID 17925401 DOI: 10.1074/Jbc.M706517200  0.589
2007 Gong X, Kole L, Iskander K, Jaiswal AK. NRH:quinone oxidoreductase 2 and NAD(P)H:quinone oxidoreductase 1 protect tumor suppressor p53 against 20s proteasomal degradation leading to stabilization and activation of p53. Cancer Research. 67: 5380-8. PMID 17545619 DOI: 10.1158/0008-5472.Can-07-0323  0.34
2007 Jain AK, Jaiswal AK. GSK-3beta acts upstream of Fyn kinase in regulation of nuclear export and degradation of NF-E2 related factor 2. The Journal of Biological Chemistry. 282: 16502-10. PMID 17403689 DOI: 10.1074/Jbc.M611336200  0.557
2006 Kannan S, Jaiswal AK. Low and high dose UVB regulation of transcription factor NF-E2-related factor 2. Cancer Research. 66: 8421-9. PMID 16951152 DOI: 10.1158/0008-5472.Can-06-1181  0.567
2006 Iskander K, Li J, Han S, Zheng B, Jaiswal AK. NQO1 and NQO2 regulation of humoral immunity and autoimmunity. The Journal of Biological Chemistry. 281: 30917-24. PMID 16905546 DOI: 10.1074/Jbc.M605809200  0.411
2006 Su S, Adikesavan AK, Jaiswal AK. Si RNA inhibition of GRP58 associated with decrease in mitomycin C-induced DNA cross-linking and cytotoxicity. Chemico-Biological Interactions. 162: 81-7. PMID 16806134 DOI: 10.1016/J.Cbi.2006.05.009  0.327
2006 Celli CM, Tran N, Knox R, Jaiswal AK. NRH:quinone oxidoreductase 2 (NQO2) catalyzes metabolic activation of quinones and anti-tumor drugs. Biochemical Pharmacology. 72: 366-76. PMID 16765324 DOI: 10.1016/J.Bcp.2006.04.029  0.369
2006 Kwang SA, Sethi G, Jain AK, Jaiswal AK, Aggarwal BB. Genetic deletion of NAD(P)H:quinone oxidoreductase 1 abrogates activation of nuclear factor-κB, IκBα kinase, c-Jun N-terminal kinase, Akt, p38, and p44/42 mitogen-activated protein kinases and potentiates apoptosis Journal of Biological Chemistry. 281: 19798-19808. PMID 16682409 DOI: 10.1074/Jbc.M601162200  0.506
2006 Wang W, Jaiswal AK. Nuclear factor Nrf2 and antioxidant response element regulate NRH:quinone oxidoreductase 2 (NQO2) gene expression and antioxidant induction. Free Radical Biology & Medicine. 40: 1119-30. PMID 16545679 DOI: 10.1016/J.Freeradbiomed.2005.10.063  0.544
2006 Jain AK, Jaiswal AK. Phosphorylation of tyrosine 568 controls nuclear export of Nrf2. The Journal of Biological Chemistry. 281: 12132-42. PMID 16513647 DOI: 10.1074/Jbc.M511198200  0.573
2005 Iskander K, Jaiswal AK. Quinone oxidoreductases in protection against myelogenous hyperplasia and benzene toxicity. Chemico-Biological Interactions. 153: 147-57. PMID 15935811 DOI: 10.1016/J.Cbi.2005.03.019  0.35
2005 Jain AK, Bloom DA, Jaiswal AK. Nuclear import and export signals in control of Nrf2. The Journal of Biological Chemistry. 280: 29158-68. PMID 15901726 DOI: 10.1074/Jbc.M502083200  0.52
2005 Iskander K, Gaikwad A, Paquet M, Long DJ, Brayton C, Barrios R, Jaiswal AK. Lower induction of p53 and decreased apoptosis in NQO1-null mice lead to increased sensitivity to chemical-induced skin carcinogenesis. Cancer Research. 65: 2054-8. PMID 15781611 DOI: 10.1158/0008-5472.Can-04-3157  0.349
2005 Dhakshinamoorthy S, Jain AK, Bloom DA, Jaiswal AK. Bach1 competes with Nrf2 leading to negative regulation of the antioxidant response element (ARE)-mediated NAD(P)H:quinone oxidoreductase 1 gene expression and induction in response to antioxidants. The Journal of Biological Chemistry. 280: 16891-900. PMID 15734732 DOI: 10.1074/Jbc.M500166200  0.573
2004 Bae I, Fan S, Meng Q, Rih JK, Kim HJ, Kang HJ, Xu J, Goldberg ID, Jaiswal AK, Rosen EM. BRCA1 induces antioxidant gene expression and resistance to oxidative stress. Cancer Research. 64: 7893-909. PMID 15520196 DOI: 10.1158/0008-5472.Can-04-1119  0.539
2004 Wang W, Jaiswal AK. Sp3 repression of polymorphic human NRH:quinone oxidoreductase 2 gene promoter. Free Radical Biology & Medicine. 37: 1231-43. PMID 15451063 DOI: 10.1016/J.Freeradbiomed.2004.06.042  0.414
2004 Zhou GD, Randerath K, Donnelly KC, Jaiswal AK. Effects of NQO1 deficiency on levels of cyclopurines and other oxidative DNA lesions in liver and kidney of young mice. International Journal of Cancer. Journal International Du Cancer. 112: 877-83. PMID 15386390 DOI: 10.1002/Ijc.20375  0.331
2004 Sankaranarayanan K, Jaiswal AK. Nrf3 negatively regulates antioxidant-response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene. The Journal of Biological Chemistry. 279: 50810-7. PMID 15385560 DOI: 10.1074/Jbc.M404984200  0.555
2004 Iskander K, Paquet M, Brayton C, Jaiswal AK. Deficiency of NRH:quinone oxidoreductase 2 increases susceptibility to 7,12-dimethylbenz(a)anthracene and benzo(a)pyrene-induced skin carcinogenesis. Cancer Research. 64: 5925-8. PMID 15342368 DOI: 10.1158/0008-5472.Can-04-0763  0.326
2004 Jaiswal AK. Nrf2 signaling in coordinated activation of antioxidant gene expression. Free Radical Biology & Medicine. 36: 1199-207. PMID 15110384 DOI: 10.1016/J.Freeradbiomed.2004.02.074  0.627
2004 Jaiswal AK. Regulation of antioxidant response element-dependent induction of detoxifying enzyme synthesis. Methods in Enzymology. 378: 221-38. PMID 15038972 DOI: 10.1016/S0076-6879(04)78018-0  0.5
2004 Suh JH, Shenvi SV, Dixon BM, Liu H, Jaiswal AK, Liu RM, Hagen TM. Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid. Proceedings of the National Academy of Sciences of the United States of America. 101: 3381-6. PMID 14985508 DOI: 10.1073/Pnas.0400282101  0.36
2003 Bloom DA, Jaiswal AK. Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression. The Journal of Biological Chemistry. 278: 44675-82. PMID 12947090 DOI: 10.1074/Jbc.M307633200  0.622
2003 Chen XL, Varner SE, Rao AS, Grey JY, Thomas S, Cook CK, Wasserman MA, Medford RM, Jaiswal AK, Kunsch C. Laminar flow induction of antioxidant response element-mediated genes in endothelial cells. A novel anti-inflammatory mechanism. The Journal of Biological Chemistry. 278: 703-11. PMID 12370194 DOI: 10.1074/Jbc.M203161200  0.49
2002 De Haan LH, Boerboom AM, Rietjens IM, van Capelle D, De Ruijter AJ, Jaiswal AK, Aarts JM. A physiological threshold for protection against menadione toxicity by human NAD(P)H:quinone oxidoreductase (NQO1) in Chinese hamster ovary (CHO) cells. Biochemical Pharmacology. 64: 1597-603. PMID 12429349 DOI: 10.1016/S0006-2952(02)01383-7  0.387
2002 Long DJ, Iskander K, Gaikwad A, Arin M, Roop DR, Knox R, Barrios R, Jaiswal AK. Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity. The Journal of Biological Chemistry. 277: 46131-9. PMID 12351651 DOI: 10.1074/Jbc.M208675200  0.316
2002 Dhakshinamoorthy S, Jaiswal AK. c-Maf negatively regulates ARE-mediated detoxifying enzyme genes expression and anti-oxidant induction. Oncogene. 21: 5301-12. PMID 12149651 DOI: 10.1038/Sj.Onc.1205642  0.521
2002 Bloom D, Dhakshinamoorthy S, Jaiswal AK. Site-directed mutagenesis of cysteine to serine in the DNA binding region of Nrf2 decreases its capacity to upregulate antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene. Oncogene. 21: 2191-200. PMID 11948402 DOI: 10.1038/Sj.Onc.1205288  0.533
2001 Long DJ, Waikel RL, Wang XJ, Roop DR, Jaiswal AK. NAD(P)H:quinone oxidoreductase 1 deficiency and increased susceptibility to 7,12-dimethylbenz[a]-anthracene-induced carcinogenesis in mouse skin. Journal of the National Cancer Institute. 93: 1166-70. PMID 11481389 DOI: 10.1093/Jnci/93.15.1166  0.308
2001 Dhakshinamoorthy S, Jaiswal AK. Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene. Oncogene. 20: 3906-17. PMID 11439354 DOI: 10.1038/Sj.Onc.1204506  0.535
2001 Gaikwad A, Long DJ, Stringer JL, Jaiswal AK. In vivo role of NAD(P)H:quinone oxidoreductase 1 (NQO1) in the regulation of intracellular redox state and accumulation of abdominal adipose tissue. The Journal of Biological Chemistry. 276: 22559-64. PMID 11309386 DOI: 10.1074/Jbc.M101053200  0.302
2001 Jaiswal AK. Regulation of genes encoding NAD(P)H:quinone oxidoreductases. Free Radical Biology & Medicine. 29: 254-62. PMID 11035254 DOI: 10.1016/S0891-5849(00)00306-3  0.567
2001 Dhakshinamoorthy S, Jaiswal AK. Small maf (MafG and MafK) proteins negatively regulate antioxidant response element-mediated expression and antioxidant induction of the NAD(P)H:Quinone oxidoreductase1 gene. The Journal of Biological Chemistry. 275: 40134-41. PMID 11013233 DOI: 10.1074/Jbc.M003531200  0.561
2000 Long DJ, Jaiswal AK. NRH:quinone oxidoreductase2 (NQO2). Chemico-Biological Interactions. 129: 99-112. PMID 11154737 DOI: 10.1016/S0009-2797(00)00200-3  0.466
2000 Long DJ, Jaiswal AK. Mouse NRH:quinone oxidoreductase (NQO2): cloning of cDNA and gene- and tissue-specific expression. Gene. 252: 107-17. PMID 10903442 DOI: 10.1016/S0378-1119(00)00221-3  0.468
2000 Dhakshinamoorthy S, Long DJ, Jaiswal AK. Antioxidant regulation of genes encoding enzymes that detoxify xenobiotics and carcinogens. Current Topics in Cellular Regulation. 36: 201-16. PMID 10842753 DOI: 10.1016/S0070-2137(01)80009-1  0.537
2000 Joseph P, Long DJ, Klein-Szanto AJ, Jaiswal AK. Role of NAD(P)H:quinone oxidoreductase 1 (DT diaphorase) in protection against quinone toxicity. Biochemical Pharmacology. 60: 207-14. PMID 10825465 DOI: 10.1016/S0006-2952(00)00321-X  0.331
2000 Joseph P, Jaiswal AK. A unique cytosolic activity related but distinct from NQO1 catalyses metabolic activation of mitomycin C. British Journal of Cancer. 82: 1305-11. PMID 10755406 DOI: 10.1054/bjoc.1999.1096  0.311
2000 Jeyapaul J, Jaiswal AK. Nrf2 and c-Jun regulation of antioxidant response element (ARE)-mediated expression and induction of gamma-glutamylcysteine synthetase heavy subunit gene. Biochemical Pharmacology. 59: 1433-9. PMID 10751553 DOI: 10.1016/S0006-2952(00)00256-2  0.501
2000 Jaiswal AK. Characterization and partial purification of microsomal NAD(P)H:quinone oxidoreductases. Archives of Biochemistry and Biophysics. 375: 62-8. PMID 10683249 DOI: 10.1006/Abbi.1999.1650  0.395
1999 Radjendirane V, Jaiswal AK. Antioxidant response element-mediated 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induction of human NAD(P)H:quinone oxidoreductase 1 gene expression. Biochemical Pharmacology. 58: 1649-55. PMID 10535757 DOI: 10.1016/S0006-2952(99)00245-2  0.493
1999 Radjendirane V, Jaiswal AK. Coordinated induction of the c-jun gene with genes encoding quinone oxidoreductases in response to xenobiotics and antioxidants. Biochemical Pharmacology. 58: 597-603. PMID 10413296 DOI: 10.1016/S0006-2952(99)00143-4  0.494
1999 Wilkinson J, Radjendirane V, Pfeiffer GR, Jaiswal AK, Clapper ML. Disruption of c-Fos leads to increased expression of NAD(P)H:quinone oxidoreductase1 and glutathione S-transferase. Biochemical and Biophysical Research Communications. 253: 855-8. PMID 9918819 DOI: 10.1006/Bbrc.1998.9804  0.342
1999 Metodiewa D, Jaiswal AK, Cenas N, Dickancaité E, Segura-Aguilar J. Quercetin may act as a cytotoxic prooxidant after its metabolic activation to semiquinone and quinoidal product. Free Radical Biology & Medicine. 26: 107-16. PMID 9890646 DOI: 10.1016/S0891-5849(98)00167-1  0.342
1998 Venugopal R, Jaiswal AK. Nrf2 and Nrf1 in association with Jun proteins regulate antioxidant response element-mediated expression and coordinated induction of genes encoding detoxifying enzymes Oncogene. 17: 3145-3156. PMID 9872330 DOI: 10.1038/Sj.Onc.1202237  0.564
1998 Montano MM, Jaiswal AK, Katzenellenbogen BS. Transcriptional regulation of the human quinone reductase gene by antiestrogen-liganded estrogen receptor-α and estrogen receptor-β Journal of Biological Chemistry. 273: 25443-25449. PMID 9738013 DOI: 10.1074/Jbc.273.39.25443  0.469
1998 Kruyt FA, Hoshino T, Liu JM, Joseph P, Jaiswal AK, Youssoufian H. Abnormal Microsomal Detoxification Implicated in Fanconi Anemia Group C by Interaction of the FAC Protein With NADPH Cytochrome P450 Reductase Blood. 92: 3050-3056. DOI: 10.1182/Blood.V92.9.3050  0.386
1996 Venugopal R, Jaiswal AK. Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene Proceedings of the National Academy of Sciences of the United States of America. 93: 14960-14965. PMID 8962164 DOI: 10.1073/Pnas.93.25.14960  0.55
1996 Xie T, Jaiswal AK. AP-2-mediated regulation of human NAD(P)H:quinone oxidoreductase1 (NQO1) gene expression Biochemical Pharmacology. 51: 771-778. PMID 8602872 DOI: 10.1016/0006-2952(95)02394-1  0.378
1995 Xie T, Belinsky M, Xu Y, Jaiswal AK. ARE- and TRE-mediated regulation of gene expression. Response to xenobiotics and antioxidants. The Journal of Biological Chemistry. 270: 6894-900. PMID 7896838 DOI: 10.1074/jbc.270.12.6894  0.365
1994 Joseph P, Jaiswal AK. NAD(P)H:quinone oxidoreductase1 (DT diaphorase) specifically prevents the formation of benzo[a]pyrene quinone-DNA adducts generated by cytochrome P4501A1 and P450 reductase Proceedings of the National Academy of Sciences of the United States of America. 91: 8413-8417. PMID 8078896 DOI: 10.1073/Pnas.91.18.8413  0.325
1994 Li Y, Jaiswal AK. Human antioxidant-response-element-mediated regulation of type 1 NAD(P)H:quinone oxidoreductase gene expression. Effect of sulfhydryl modifying agents. European Journal of Biochemistry. 226: 31-9. PMID 7957257 DOI: 10.1111/j.1432-1033.1994.tb20023.x  0.37
1993 Belinsky M, Jaiswal AK. NAD(P)H:quinone oxidoreductase1 (DT-diaphorase) expression in normal and tumor tissues. Cancer Metastasis Reviews. 12: 103-17. PMID 8375015 DOI: 10.1007/BF00689804  0.396
1992 Li Y, Jaiswal AK. Identification of jun-B as third member in human antioxidant response element-nuclear proteins complex. Biochemical and Biophysical Research Communications. 188: 992-6. PMID 1445367 DOI: 10.1016/0006-291X(92)91329-O  0.3
1990 Jaiswal AK, Haaparanta T, Luc PV, Schembri J, Adesnik M. Glucocorticoid regulation of a phenobarbital-inducible cytochrome P-450 gene: the presence of a functional glucocorticoid response element in the 5'-flanking region of the CYP2B2 gene. Nucleic Acids Research. 18: 4237-42. PMID 2377462 DOI: 10.1093/nar/18.14.4237  0.319
1987 Neuhold LA, Gonzalez FJ, Jaiswal AK, Nebert DW. Dioxin-inducible enhancer region upstream from the mouse P(1)450 gene and interaction with a heterologous SV40 promoter. Dna (Mary Ann Liebert, Inc.). 5: 403-11. PMID 3023000 DOI: 10.1089/dna.1986.5.403  0.354
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