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Constance L. Cepko

Affiliations: 
Genetics Harvard Medical School, Boston, MA, United States 
Area:
development of the central nervous system of vertebrates, with an emphasis on the development of the retina; mechanisms of photoreceptor degeneration, and gene therapy for prevention of blindness
Website:
http://genetics.med.harvard.edu/faculty/cepko
Google:
"Constance L. Cepko"
Bio:

http://genepath.med.harvard.edu/~cepko/

Cross-listing: Neurotree - Neuropathology Tree

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Parents

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Phillip Allen Sharp grad student MIT (Chemistry Tree)
Richard Mulligan post-doc Harvard

Children

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David Altshuler grad student Harvard (Neurotree)
Christopher P. Austin grad student Harvard (Neurotree)
Eric Morrow grad student Harvard Medical School (Neurotree)
Sheila Nirenberg grad student Harvard (Neurotree)
David Turner grad student Harvard (Neurotree)
Santiago Rompani grad student 2005- Harvard Medical School (Neurotree)
Maureen A. Peters grad student 2002 Harvard (Neurotree)
Sheldon S. Rowan grad student 2003 Harvard (Neurotree)
Tracy L. Young-Pearse grad student 1997-2004 Harvard University/Brigham and Women's (Neurotree)
Sanjiv Harpavat grad student 2005 Harvard (Neurotree)
Ashutosh P. Jadhav grad student 2005 Harvard (Neurotree)
Timothy J. Cherry grad student 2002-2009 Harvard (Neurotree)
Nathan A. Billings grad student 2011 Harvard (Neurotree)
Karolina Mizeracka grad student 2012 Harvard (Neurotree)
Raffaele Sarnataro grad student 2016-2016 Harvard Medical School (Neurotree)
Sean K. Wang grad student 2015-2021 Harvard Medical School (Neurotree)
Zheng-Zheng Bao post-doc Harvard Medical School (Neurotree)
Michael A. Dyer post-doc Harvard Medical School (Neurotree)
Jeffrey A. Golden post-doc Harvard Medical School (Neurotree)
Francois P. Guillemot post-doc Harvard Medical School (Neurotree)
Sylvain Lapan post-doc (Neurotree)
Laura E. Lillian post-doc Harvard Medical School (Neurotree)
Nicolas Lonfat post-doc Harvard Medical School (DevTree)
Xiang Ma post-doc Harvard Medical School (Neurotree)
Evan Y. Snyder post-doc Harvard Medical School (Neurotree)
Francis Szele post-doc Harvard (Neurotree)
Jeffrey Trimarchi post-doc (Neurotree)
Chris A. Walsh post-doc Harvard (Neurotree)
Doris K. Wu post-doc (Neurotree)
Rinaldo Catta-Preta post-doc 2020- Harvard Medical School (Evolution Tree)
Joseph J. LoTurco post-doc 1992-1994 Harvard Medical School (Neurotree)
Xianjie Yang post-doc 1989-1996 Harvard Medical School (Neurotree)
Dorothea Schulte post-doc 1996-1999 Harvard (Neurotree)
Li Cai post-doc 1997-2000 Harvard Medical School (Neurotree)
Frederick Livesey post-doc 1998-2001 Harvard Medical School (Neurotree)
Seth Blackshaw post-doc 1999-2004 Harvard Medical School (Neurotree)
Joseph C. Corbo post-doc 2002-2005 Harvard Medical School (Neurotree)
Botond M. Roska post-doc 2002-2005 Harvard Medical School (Neurotree)
Douglas S. Kim post-doc 2002-2008 Harvard Medical School (Neurotree)
Rahul N. Kanadia post-doc 2005-2010 Harvard Medical School (Microtree)

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Publications

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Xue Y, Zhou Y, Cepko CL. (2024) Txnip deletions and missense alleles prolong the survival of cones in a retinitis pigmentosa mouse model. Biorxiv : the Preprint Server For Biology
Avilés EC, Wang SK, Patel S, et al. (2023) High temporal frequency light response in mouse retina is mediated by ON and OFF bipolar cells and requires FAT3 signaling. Biorxiv : the Preprint Server For Biology
Xue Y, Sun X, Wang SK, et al. (2023) Chromophore supply modulates cone function and survival in retinitis pigmentosa mouse models. Proceedings of the National Academy of Sciences of the United States of America. 120: e2217885120
Wang SK, Cepko CL. (2022) Targeting Microglia to Treat Degenerative Eye Diseases. Frontiers in Immunology. 13: 843558
Aytürk DG, You W, Cepko CL. (2022) Mouse Lines with Cre-mediated Recombination in Retinal Amacrine Cells. Eneuro
West ER, Lapan SW, Lee C, et al. (2022) Spatiotemporal patterns of neuronal subtype genesis suggest hierarchical development of retinal diversity. Cell Reports. 38: 110191
West ER, Cepko CL. (2021) Development and diversification of bipolar interneurons in the mammalian retina. Developmental Biology
Wang SK, Xue Y, Cepko CL. (2021) Augmentation of CD47-SIRPα signaling protects cones in genetic models of retinal degeneration. Jci Insight
Xue Y, Wang SK, Rana P, et al. (2021) AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa. Elife. 10
Chan YK, Wang SK, Chu CJ, et al. (2021) Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses. Science Translational Medicine. 13
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