Nerea Zabaleta

Affiliations: 
Harvard Medical School - Massachusetts Eye and Ear 
Area:
Gene therapy, adeno-associated virus, inherited disorders, liver, infectious diseases, vaccines
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"Nerea Zabaleta"
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Doshi J, Couto E, Staiti J, et al. (2024) E2A, VA RNA I, and L4-22k adenoviral helper genes are sufficient for AAV production in HEK293 cells. Molecular Therapy. Methods & Clinical Development. 32: 101376
Bhatt U, Herate C, Estelien R, et al. (2024) Boost and Increased Antibody Breadth Following a Second Dose of PARVAX for SARS-CoV-2 in Mice and Nonhuman Primates. Vaccines. 12
Torella L, Santana-Gonzalez N, Zabaleta N, et al. (2024) Gene editing in liver diseases. Febs Letters
Torella L, Klermund J, Bilbao-Arribas M, et al. (2024) Efficient and safe therapeutic use of paired Cas9-nickases for primary hyperoxaluria type 1. Embo Molecular Medicine. 16: 112-131
Kumar P, Wang M, Kumru OS, et al. (2023) Correlating physicochemical and biological properties to define critical quality attributes of a rAAV vaccine candidate. Molecular Therapy. Methods & Clinical Development. 30: 103-121
Reichart D, Newby GA, Wakimoto H, et al. (2023) Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice. Nature Medicine
Zabaleta N, Unzu C, Weber ND, et al. (2023) Gene therapy for liver diseases - progress and challenges. Nature Reviews. Gastroenterology & Hepatology
Zinn E, Unzu C, Schmit PF, et al. (2022) Ancestral library identifies conserved reprogrammable liver motif on AAV capsid. Cell Reports. Medicine. 100803
Zabaleta N, Bhatt U, Hérate C, et al. (2022) Durable immunogenicity, adaptation to emerging variants and low dose efficacy of AAV-based COVID19 platform in macaques. Molecular Therapy : the Journal of the American Society of Gene Therapy
Maciorowski D, Diop C, Bhatt U, et al. (2022) Immunogenicity of an AAV-Based COVID-19 Vaccine in Murine Models of Obesity and Aging. Viruses. 14
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