Anthony Bruce Pinkerton
Affiliations: | 1996-2001 | Chemistry | Stanford University, Palo Alto, CA |
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"Anthony Pinkerton"Mean distance: 7.64 | S | N | B | C | P |
Parents
Sign in to add mentor| Barry M. Trost | grad student | 1996-2001 | Stanford | |
| (The development of new ruthenium -catalyzed reactions and a new strategy for cyclopentenone synthesis.) | ||||
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Publications
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| Pinkerton AB, Peddibhotla S, Yamamoto F, et al. (2019) Discovery of b-Arrestin Biased, Orally Bioavailable and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators. Journal of Medicinal Chemistry |
| Gardell SJ, Hopf M, Khan A, et al. (2019) Boosting NAD with a small molecule that activates NAMPT. Nature Communications. 10: 3241 |
| Feng Y, Sessions EH, Zhang F, et al. (2019) Identification and characterization of small molecule inhibitors of the ubiquitin ligases Siah1/2 in melanoma and prostate cancer cells. Cancer Letters |
| Pinkerton AB, Sergienko E, Bravo Y, et al. (2018) Discovery of 5-((5-chloro-2-methoxyphenyl)sulfonamido)nicotinamide (SBI-425), a potent and orally bioavailable tissue-nonspecific alkaline phosphatase (TNAP) inhibitor. Bioorganic & Medicinal Chemistry Letters. 28: 31-34 |
| Villarino N, Signaevskaia L, van Niekerk J, et al. (2017) A screen for inducers of bHLH activity identifies pitavastatin as a regulator of p21, Rb phosphorylation and E2F target gene expression in pancreatic cancer. Oncotarget. 8: 53154-53167 |
| Ziegler SG, Ferreira CR, MacFarlane EG, et al. (2017) Ectopic calcification in pseudoxanthoma elasticum responds to inhibition of tissue-nonspecific alkaline phosphatase. Science Translational Medicine. 9 |
| Shiryaev SA, Farhy C, Pinto A, et al. (2017) Characterization of the Zika virus two-component NS2B-NS3 protease and structure-assisted identification of allosteric small-molecule antagonists. Antiviral Research |
| Li J, Yakushi T, Parlati F, et al. (2017) Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11. Nature Chemical Biology |
| Peddibhotla S, Fontaine P, Leung CK, et al. (2015) Discovery of ML358, a Selective Small Molecule Inhibitor of the SKN-1 Pathway Involved in Drug Detoxification and Resistance in Nematodes. Acs Chemical Biology. 10: 1871-9 |
| Roemeling CAV, Caulfield TR, Radisky DC, et al. (2015) Abstract 4459: Accelerated drug discovery platform yields synthesis of novel stearoyl-CoA desaturase 1 inhibitors that demonstrate anti-tumor efficacy in several models of aggressive cancer Cancer Research. 75: 4459-4459 |