Thomas E. Prisinzano

Affiliations: 
University of Kansas, Lawrence, KS, United States 
Area:
Opioids, Pain, Drug abuse
Website:
http://medchem.ku.edu/thomas-prisinzano
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Parents

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Richard A. Glennon grad student 2000 VCU
 (Development of h5-HT(10) serotonergic ligands as potential antimigraine agents.)
Kenner C. Rice post-doc 2000-2003 NIH - NIDDK
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Publications

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Zamarripa CA, Huskinson SL, Townsend EA, et al. (2023) Contingent administration of typical and biased kappa opioid agonists reduces cocaine and oxycodone choice in a drug vs. food choice procedure in male rhesus monkeys. Psychopharmacology
Huskinson SL, Platt DM, Smith ZR, et al. (2023) Quantification of observable behaviors following oral administration of oxycodone and nalfurafine in male rhesus monkeys. Drug and Alcohol Dependence. 252: 110953
Chambers DR, Sulima A, Luo D, et al. (2023) A MOR Antagonist with High Potency and Antagonist Efficacy among Diastereomeric C9-Alkyl-Substituted -Phenethyl-5-(3-hydroxy)phenylmorphans. Molecules (Basel, Switzerland). 28
van de Wetering R, Ewald A, Welsh S, et al. (2023) The Kappa Opioid Receptor Agonist 16-Bromo Salvinorin A Has Anti-Cocaine Effects without Significant Effects on Locomotion, Food Reward, Learning and Memory, or Anxiety and Depressive-like Behaviors. Molecules (Basel, Switzerland). 28
Lutz JA, Sulima A, Gutman ES, et al. (2023) Discovery of a Potent Highly Biased MOR Partial Agonist among Diastereomeric C9-Hydroxyalkyl-5-phenylmorphans. Molecules (Basel, Switzerland). 28
Chambers DR, Sulima A, Luo D, et al. (2022) A Journey through Diastereomeric Space: The Design, Synthesis, In Vitro and In Vivo Pharmacological Activity, and Molecular Modeling of Novel Potent Diastereomeric MOR Agonists and Antagonists. Molecules (Basel, Switzerland). 27
Shelton CL, Meneely KM, Ronnebaum TA, et al. (2022) Rational inhibitor design for Pseudomonas aeruginosa salicylate adenylation enzyme PchD. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry
Huskinson SL, Platt DM, Zamarripa CA, et al. (2022) The G-protein biased kappa opioid agonists, triazole 1.1 and nalfurafine, produce non-uniform behavioral effects in male rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 217: 173394
Paton KF, Luo D, La Flamme AC, et al. (2022) Sex Differences in Kappa Opioid Receptor Agonist Mediated Attenuation of Chemotherapy-Induced Neuropathic Pain in Mice. Frontiers in Pharmacology. 13: 813562
Hedrick SL, Luo D, Kaska S, et al. (2021) Design, synthesis, and preliminary evaluation of a potential synthetic opioid rescue agent. Journal of Biomedical Science. 28: 62
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